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http://dx.doi.org/10.5764/TCF.2019.31.4.323

Bioactive Characteristics of Sorghum Extract/Poly(vinyl alcohol) Composite Nanoweb Produced by Electrospinning  

Lee, Hyun Ju (Korea Dyeing and Finishing Technology Institute)
Jeon, Jae Woo (Korea Dyeing and Finishing Technology Institute)
Jung, So Yeon (Department of Biofibers and Biomaterials Science, Kyungpook National University)
Choi, Jin Hyun (Department of Biofibers and Biomaterials Science, Kyungpook National University)
Publication Information
Textile Coloration and Finishing / v.31, no.4, 2019 , pp. 323-331 More about this Journal
Abstract
Sorghum is a rich source in phytochemicals, such as tannins, phenolic acids, anthocyanins, phytosterols and policosanols. Sorghum has been known to have antimicrobial, antiinflammatory, antioxidant properties. In this study, poly(vinyl alcohol)(PVA)-sorghum extract(SE) composite nanoweb was produced by electrospinning and its characteristics including bioactivities were investigated. The SE had antimicrobial and antiinflammatory activities as well as a reduced cytotoxicity. The PVA-SE nanoweb had a highly enhanced antimicrobial activity compared to PVA nanoweb. The amount of proinflammatory cytokine released from macrophages treated with the PVA-SE nanoweb was reduced. The PVA-SE nanoweb can be a potential candidate for medical and cosmeceutical materials providing antimicrobial and antiinflammatory activities with a low degree of cytotoxicity.
Keywords
sorghum; poly(vinyl alcohol); electrospinning; antimicrobial and antiinflammatory activities; cytotoxicity;
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