Browse > Article
http://dx.doi.org/10.3839/jksabc.2008.047

Inhibitory Effect of Ore Minerals on the Allergic Inflammation in Mouse  

Park, Seul-Ki (Department of Medical Biotechnology, Soonchunhyang University)
Lee, Chang-Won (NT&BT Co. Ltd. Research Institute)
Lee, Mi-Young (Department of Medical Biotechnology, Soonchunhyang University)
Publication Information
Applied Biological Chemistry / v.51, no.4, 2008 , pp. 269-275 More about this Journal
Abstract
The ore minerals, mainly composed of sericite, talc, and halloysite, were investigated for their inhibitory effect on the allergic inflammation in mice by measuring the serum IgE level, inflammatory cytokine production, and histamine and ${\beta}$-hexosaminidase releases. When the mice were ovalbumin (OVA)-challenged prior to the ore mineral treatment, the IgE level in the serum decreased significantly. The ore minerals significantly reduced the productions of IL-4 and the tumor necrosis factor-${\alpha}$ in the bronchial alveolar lavage fluid challenged with OVA. The inflammatory infiltrates, found in the lung of the OVA-challenged mouse, were also notably decreased following the ore mineral treatment. The ore minerals significantly reduced the release of histamine and ${\beta}$-hexosaminidase from the RBL-2H3 cells. These results suggest that the ore minerals may be useful as potent inhibitors of the allergic inflammation in mice.
Keywords
allergic inflammation; cytokine; histamine; IgE; ore minerals;
Citations & Related Records
Times Cited By KSCI : 8  (Citation Analysis)
Times Cited By Web Of Science : 3  (Related Records In Web of Science)
연도 인용수 순위
1 Barsumian EL, Isersky C, Petrino MG, and Siraganian RP (1981) IgE-induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones. Eur J Immunol 11, 317-323   DOI   ScienceOn
2 Kim SC and Byun SH (2005) The effects of oldenlandiae diffusae herba extract on eosinophil, IgE and IL-4 on experimental asthma induced by ovalbumin. Kor J Herbology 20, 35-42
3 Nakatani K, Atsumi M, Arakawa T, Oosawa K, Shimura S, Nakahata N, and Ohizumi Y (2002) Inhibitions of histamine release and prostaglandin E2 synthesis by mangosteen, a Thai medicinal plant. Biol Pharm Bull 25, 1137-1141   DOI   ScienceOn
4 Yamashita K, Suzuki Y, Matsui T, Yoshimaru T, Yamaki M, Suzuki-Karasaki M, Hayakawa S, and Shimizu K (2000) Epigallocatechin gallate inhibits histamine release from rat basophilic leukemia (RBL-2H3) cells: role of tyrosine phosphorylation pathway. Biochem Biophys Res Commun 274, 603-608   DOI   ScienceOn
5 Yi JM, Kim MS, Seo SW, Lee KN, Yook CS, and Kim HM (2001) Acanthopanax senticosus root inhibits mast celldependent anaphylaxis. Clin Chim Acta 312, 163-168   DOI   ScienceOn
6 Lee JS, Park YM, Park BH, Jung KS, Kim KH, Lee WH, and Park DH (2003) Evaluation of the anti-inflammatory and immunomodulatory effects of BSASM using in vitro experiments. Kor J Pharmacogn 34, 228-232   과학기술학회마을
7 Metcalfe DD, Kaliner M, and Donlon MA (1981) The mast cell. Crit Rev Immunol 3, 23-74
8 Jeon YM, Ryu JC, and Lee MY (2007) Proteomic analysis of differentially expressed proteins in human lung cells following formaldehyde treatment. Mol Cell Toxicol 3, 238-245   과학기술학회마을
9 Fish SC, Donaldson DD, Goldman SJ, Williams CM, and Kasaian MT (2005) IgE generation and mast cell effector function in mice deficient in IL-4 and IL-13. J Immunol 174, 7716-7724   DOI
10 Lee MR, Han CS, Han DY, Park EJ, Lee SC, and Park HR (2008) Protective effect of neuronal cell on glutamateinduced oxidative stress from viola mandshurica extracts. J Korean Soc Appl Biol Chem 51, 79-83   과학기술학회마을
11 Kim SH, Jun CD, Suk KH, Choi BJ, Lim HJ, Park SJ, Lee SH, Shin HY, Kim DK, and Shin TY (2006) Gallic acid inhibits histamine release and pro-inflammatory cytokine production in mast cells. Toxicol Sci 91, 123-131   DOI   ScienceOn
12 Metzger H (1992) The receptor with high affinity for IgE. Immunol Rev 125, 37-48   DOI
13 Averbeck M, Gebhardt C, Emmrich F, Treudler R, and Simon JC (2007) Immunologic principles of allergic disease. J Dtsch Dermatol Ges 5, 1015-1028   DOI   ScienceOn
14 Bradding P, Feather IH, Wilson S, Bardin PG, Heusser CH, Holgate ST, and Howarth PH (1993) Immunolocalization of cytokines in the nasal mucosa of normal and perennial rhinitic subjects. The mast cell as a source of IL-4, IL-5 and IL-6 in human allergic mucosal inflammation. J Immunol 151, 3853-3865
15 Choi KM, Lee CW, and Lee MY (2008) Effect of ore minerals on the healing of full-thickness skin injury model of rat. J Environ Sci 17, 809-816   과학기술학회마을   DOI
16 Xu X, Zhang D, Zhang H, Wolters PJ, Killeen NP, Sullivan BM, Locksley RM, Lowell CA, and Caughey GH (2006) Neutrophil histamine contributes to inflammation in mycoplasma pneumonia. J Exp Med 203, 2907-2917   DOI   ScienceOn
17 Benhamou M, Ryba NJ, Kihara H, Nishikata H, and Siraganian RP (1993) Protein-tyrosine kinase p72syk in high affinity IgE receptor signaling. Identification as a component of pp72 and association with the receptor gamma chain after receptor aggregation. J Biol Chem 268, 23318-23324
18 Park SK, Kim JJ, Jeon YM, and Lee MY (2007) Suppressive effects of Korean indigenous acanthopanax divaritacus on the allergic inflammation. J Appl Biol Chem 50, 155-159   과학기술학회마을
19 Jeong HS, Rhim TY, Ahn MH, Yoon PO, Kim SH, Chung IY, Uh ST, Kim SI, and Park CS (2005) Proteomic analysis of differently expressed proteins in a mouse model for allergic asthma. J Korean Med Sci 20, 579-585   DOI   ScienceOn
20 White JR, Pluznik DH, Ishizaka K, and Ishizaka T (1985) Antigen-induced increase in protein kinase C activity in plasma membrane of mast cells. Proc Natl Acad Sci USA 82, 8193-8197
21 Petersen LJ, Mosbech H, and Skov PS (1996) Allergeninduced histamine release in intact human skin in vivo assessed by skin microdialysis technique: characterization of factors influencing histamine releasability. J Allergy Clin Immunol 97, 672-679   DOI   ScienceOn
22 Sy LB, Wu YL, Chiang BL, Wang YH, and Wu WM (2006) Propolis extracts exhibit an immunoregulatory activity in an OVA-sensitized airway inflammatory animal model. Int Immunopharmacol 6, 1053-1060   DOI   ScienceOn
23 Wuthrich B (1989) Epidemiology of the allergic diseases: are they really on the increase? Int Arch Allergy Appl Immunol 90 (Suppl 1), 3-10   DOI
24 Jonathan P, Paul M, and Paul K (2001) The Biology of Disease (2nd ed.) Blackwell Science, Oxford, UK
25 Burd PR, Rogers HW, Gordon JR, Martin CA, Jayaraman S, Wilson SD, Dvorak AM, Galli SJ, and Dorf ME (1989) Interleukin 3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokines. J Exp Med 170, 245-257   DOI
26 Plaut M, Pierce JH, Watson CJ, Hanley-Hyde J, Nordan RP, and Paul WE (1989) Mast cell lines produce lymphokines in response to cross-likage of Fc epsilon RI or to calcium ionophores. Nature 339, 64-67   DOI   ScienceOn
27 Hoffmann A, Jamin A, Foetisch K, May S, Aulepp H, Haustein D, and Vieths S (1999) Determination of the allergenic activity of birch pollen and apple prick test solutions by measurement of $\beta$-hexosaminidase release from RBL-2H3 cells. Comparison with classical methods in allergen standardization. Allergy 54, 446-454   DOI   ScienceOn
28 Kang DK and Lee MY (2008) Photoprotective effects of minerals from Korean Indigenous Ores on UVA-irradiated human dermal fibroblast. Mol Cell Toxicol 4, 150-156   과학기술학회마을
29 Oh JH, Park HJ, Heo SH, Yang MJ, Yang YS, Song CW, and Yoon SJ (2007) Gene expression analysis of lung injury in rats induced by exposure to MMA-SS welding fume for 30 days. Mol Cell Toxicol 3, 306-313   과학기술학회마을