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A Study on the Cosmeceutical activities of Prunus Sargentii R.  

Park, Jung-Mi (Department of Cosmeceutical Science, Daegu Haany University)
Lee, Jin-Young (Department of Cosmeceutical Science, Daegu Haany University)
Park, Tae-Soon (Department of Cosmeceutical Science, Daegu Haany University)
Hyun, Sok-Jun (Department of Cosmeceutical Science, Daegu Haany University)
Kim, Han-Hyuk (Department of Cosmeceutical Science, Daegu Haany University)
Cho, Young-Je (Department of Food Engineering, Sangju National University)
Kwon, O-Jun (Gyeongbuk Regional Innovation Agency)
Son, Ae-Ryang (Department of Beauty Design, Gyeongnam Provincial Collage in Geochang)
Kim, Dong-Seok (Gounmi skin laser/aesthetic clinic)
An, Bong-Jeun (Department of Cosmeceutical Science, Daegu Haany University)
Publication Information
Applied Biological Chemistry / v.51, no.1, 2008 , pp. 70-78 More about this Journal
Abstract
Prunus sargentii R. of Rosaceae familiy, has been reported to have radical scavenging activity and anti-inflammatory effect. On these facts, biological activity and safety test were conducted to evaluate biological activities of the extracts of P. sargentii R. as a potential pharmaceutical ingredient. The electron donating ability of its ethanol extracts at a 500 ppm level showed 92%, which was higher than that of hot water extract (59%), the superoxide dismutase (SOD)-like activity of the water extract of P. sargentii R. was about 50%, the ethanol extract of P. sargentii R. was about 40% at 1,000 ppm concentration. Xanthine oxidase inhibition by the water extract of P. sargentii R. was about 40% and that by the ethanol extract was 60% respectively at 500 ppm concentration. From the measurement on lipid oxidation, the $Cu^{2+}$ chelating effect of the ethanol extract was higher than that of hot water extract. The $Fe^{2+}$ chelating effect was also shown to be about 80% at a 500 ppm concentration in both hot water extract and ethanol extract. The tyrosinase inhibition effect related to skin-whitening was 26% by hot water extract and 20% by ethanol extract respectively at a 1,000 ppm. Hyaluronidase inhibition activity related to the anti-inflammation effect was 96% in ethanolic extract at a 500 ppm. Clear zones formed by P. sargentii R. against the human skin-resident micro-flora such as Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Propionibacterium acnes indicated that antimicrobial activity of the ethanol extract was higher than that of the hot water extract.
Keywords
anti-inflammation effect; antimicrobial activity; antioxidant; Prunus sargentii R.;
Citations & Related Records
Times Cited By KSCI : 4  (Citation Analysis)
Times Cited By Web Of Science : 2  (Related Records In Web of Science)
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