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Effect of Domestic Rose Flower Extracts on the Growth of Chinese Hamster Ovary Cells  

Chun, Hye-Kyung (Division of Agriproduct Processing, Rural Resources Development Institute, National Institute of Agricultural Science and Technology)
Park, Hong-Ju (Division of Agriproduct Processing, Rural Resources Development Institute, National Institute of Agricultural Science and Technology)
Yoo, Byung-Sun (Division of Natural Science, Gyonggi University)
Cho, Yong-Sik (Division of Agriproduct Processing, Rural Resources Development Institute, National Institute of Agricultural Science and Technology)
Publication Information
Applied Biological Chemistry / v.50, no.2, 2007 , pp. 132-135 More about this Journal
Abstract
The effects of rose flower extracts on the growth of CHO cells were examined. Rose flower extracts were prepared by solvent extraction with hexane, ethylacetate and ether from five domestic rose cultivar, Rosa hybrida L. cv. Mihyang, Noeul, Redqueen, Whitelady and Pinklady, respectively. The effects of rose flower extracts on the growth of CHO cells were measured using MTT colormeteric assay and compared with control. Extracts of rose flowers showed stimulative effect or inhibitory effect on the growth of CHO cells depending on the kinds of solvent and concentration of extracts. Ether extracts of rose flower showed a more effective stimulative effect on the growth of CHO cells at the concentration of 5 ${\mu}g{\cdot}ml^{-1}$. These results suggest that rose flower has the simulating activity on the growth of CHO cells and a potential as new functional food source.
Keywords
cell growth; CHO cells; Rosa hybrida; simulating activity; solvent extracts;
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Times Cited By KSCI : 2  (Citation Analysis)
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