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Antioxidant and Antibacterial Effects of Korean Isodon japonicus H.  

An, Bong-Jeun (Department of Cosmeceutical Science, Daegu Haany University)
Park, Jung-Mi (Department of Cosmeceutical Science, Daegu Haany University)
Bae, Ho-Jung (Department of Cosmeceutical Science, Daegu Haany University)
Pyun, Jeong-Ran (Department of Cosmeceutical Science, Daegu Haany University)
Song, Mi-Ae (Department of Cosmeceutical Science, Daegu Haany University)
Publication Information
Applied Biological Chemistry / v.49, no.2, 2006 , pp. 129-134 More about this Journal
Abstract
Biological activities and application of Isodon japonicus H. were investigated. In the physiological activities, the electron donating ability (EDA) was 66.3% in 100 ppm and SOD-like activity was as high as 85.0% in 1,000 ppm with gradual increase. As for the inhibitory effect of xanthine oxidase, it was 70.0% in 1,000 ppm and as low as 40.0% in 500 ppm; also, as for the inhibitory effect of tyrosinase, it was as low as 20.5% below 1,000 ppm. The tyrosinase inhibition effect related to skin whitening function showed 30.0% at 1,000 ppm level or below, indicating a relatively low effect. As for the result of measuring the lipid oxidation, all the concentrations of medical ion treatments showed anti-acidification ability; also, as for the metal ion blocking effects against the lipid oxidation promoting factors $(Fe^{2+}\;and\;Cu^{2+})$, $Fe^{2+}$ was better than $Cu^{2+}$ and all concentrations of medical ion treatments was 60.0% in 100 ppm. Also, the clear zone against various bacteria at 0.5 and 1.0 mg/disc was clearly shown. When it was applied into a normal skin-softener, it was safe, showing its potential as a natural material of cosmetics.
Keywords
Isodon japonicus; antioxidant; antibacterial; SOD;
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