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Development of Biologically Active Compound from Edible Plant Sources-XV. Isolation of Triterpene Glycosides from the Leaf of Petasites japonicus  

Bang, Myun-Ho (The Graduate School of Biotechnology & Plant Metabolism Research Center)
Park, Jin-Kyu (Pharmaco Design Co. Ltd.)
Song, Myoung-Chong (The Graduate School of Biotechnology & Plant Metabolism Research Center)
Yang, Hye-Joung (The Graduate School of Biotechnology & Plant Metabolism Research Center)
Yoo, Jong-Su (The Graduate School of Biotechnology & Plant Metabolism Research Center)
Ahn, Eun-Mi (Scigenic Co. Ltd.)
Kim, Dae-Keun (Department of Pharmacy, Woosuk University)
Baek, Nam-In (The Graduate School of Biotechnology & Plant Metabolism Research Center)
Publication Information
Applied Biological Chemistry / v.48, no.4, 2005 , pp. 421-424 More about this Journal
Abstract
The leaf of Petasites japonicus was extracted with 80% aqueous MeOH and solvent fractionated with EtOAc, n-BuOH and water successively. From the EtOAc fractions, two triterpenoids were isolated through the repeated silica gel and ODS column chromatographies. The chemical structures of the isolated terpenoids were determined as rosamutin (1) and peduncloside (2) through the interpretation of several spectral data including 2D-NMR such as $^1H-{^1H}$ gCOSY, gHSQC and gHMBC.
Keywords
Petasites japonicus; Compositae; triterpenoid; rosamutin; peduncloside;
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