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Effect of Giant Embryonic Rice Supplementation on the Lipid Peroxide Levels and Antioxidative Enzyme Activities in the Plasma and Liver of Streptozotocin-induced Diabetic Rats  

Lee, Youn-Ri (Department of Food Science and Nutrition, Kyungpook National University)
Kang, Mi-Young (Department of Food Science and Nutrition, Kyungpook National University)
Nam, Seok-Hyun (Department of Biological Science, Ajou University)
Publication Information
Applied Biological Chemistry / v.48, no.4, 2005 , pp. 358-363 More about this Journal
Abstract
Effects on the feeds of streptozotocin-induced diabetic rats with a giant embryonic rice on lipid peroxides level and antioxidative enzyme activites in plasma and liver tissues were investigated. Along with the experimental periods, all animals in diabetic groups had a lower increase rate in body weight than the normal control group. A giant embryonic rice-fed group showed a inhibition in the decrease of body weight, and a increase in feed intake compared to the normal control group. The organ weights of the diabetic control group were heavier than those of the normal control while rice-fed groups including the giant embryonic rice-fed group were found to have lower organ weights, and its blood sugar level was found to be lower than those of the normal group. Lipid peroxides of the giant embryonic rice-fed animals showed a lower lipid peroxidation values compared to that of the diabetic control group. Plasma vitamin A and E concentrations of the diabetic control group were significantly decreased compared to the normal control while those of the giant embryonic rice-fed group were found to be significantly higher than those of the diabetic control. Of the hepatic antioxidative enzymes, SOD activity of the giant embryonic rice-fed group was higher than that of the diabetic control group. Taken these together, low lipid peroxidation values and, in contrast, high antioxidative enzyme activities were thought to be a cause for decreasing hepatic oxidative damages.
Keywords
Lipid peroxide; Diabetic rat; Streptozotocin; Antioxidative enzymes; TBARS;
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1 Sosenko, J. M., Lattimer, S. A, Kamijo, M., Van-Huysen C., Sima, A. A. and Greene, D. A. (1980) Osmotically-induced nerve taurine depletion and the compatible osmolyte hypothesis in experimental diabetic neuropathy in the rat. Diabetologia 36, 608-614   DOI   ScienceOn
2 Goldsterin, J. L. and Brown, M. S. (1997) The low-density lipoprotein pathway and its relation to atherosclerosis. Ann. Rev. Biochem. 46, 897-930   DOI   ScienceOn
3 Basu, T. K. and Basualdo, C. (1997) Vitamin A homeostasis and diabetes mellitus. Nutrition 13, 804-806   DOI   ScienceOn
4 Morel, D. W. and Chisolm, G. M. (1989) Antioxidant treatment of diabetic rats inhibitor lipoprotein oxidation and cytoxicity. J. Lipid Res, 30, 1827-1834
5 Son, H. Y. (1992) Lipoprotein(s) and diabetes mellitus. J. Korean Diabetes Assoc. 16, 275-280
6 Uchiyama, M. and Mihara, M. (1978) Determination of malondialdehyde precursor in tissuse by TBA test. Anal. Biochem. 86, 271-278   DOI   ScienceOn
7 Abei, H. (1974) In methods of enzymatic analysis Bergmeyer HU, Chemie Weinhein, F.R.G. pp. 673-684
8 Park, S. H., Lee, Y. K. and Lee, H. S. (1994) The effects of dietary fiber on gastrointestinal functions and lipid and glucose metabolism in streptozotocin induced diabetic rats. Korean. J. Nutr. 27, 311-322
9 Marklund, S. and Marklund, G. (1974) Involvement of superoxide anion radical in the antioxidation of pyrogallol and a convenient assay for superoxide disumatase. Eur. J. Biochem. 47, 469-474   DOI   ScienceOn
10 Best. J. D. (2000) Diabetic dyslipidaemia-current treatment recommendations. Drugs 59, 1101-1111   DOI   ScienceOn
11 Choi, T. W., Son, K. H and Kim, S. H (1991) The effect of nicotinamide on plasma lipid compositions in sterptozotocin induced rats. Korean J. Nutr. 20, 306-311
12 Levy, Y., Zaltsberg, H. Ben-Amotz, A, Kanter, Y. and Aviram, M. (2000) Dietary supplementation of a natural isomer mixture of $\beta$-carotene inhibits oxidation of LDL derived from patients with diabetes melitus. Ann. Nutr. Metab. 44, 54-60   DOI   ScienceOn
13 Aruna, R. V., Ramesh, B. and Kartha, V. N. (1999) Effect of $\beta$-carotene on protein glycosylation in aloxan induced diabetic rats. Indian J. Exp. Biol. 37, 399-401
14 Deisseroth A. and Dounce, A. L. (1970) Catalase physical and chemical properties, mechanism of catalysis and physiological role. Physiol. Rev. 50, 3-24
15 MeLennan, S. V., Hefferman, S. and Wright, L. (1991) Changes in hepatic glutathion metabolism in diabetes. Diabates 40, 344-348   DOI   ScienceOn
16 Sato, H. and Omura, T. (1981) New endosperm mutations induced by chemical mutagens in rice, Oyiza sativa. L.. Jpn. J. Breed. 31, 316-326
17 Dixon, L. J., Tsin, A. T. and Basu, T. K. (2000) The metabolic availability of vitamin A is decreased at the onset of diabetes in BB rats. J. Nutri. 130, 1958-1962
18 Wade, K., Miki, H., Ethoh, M. and Okuda, F. (1983) The inhibitory effects of lipid peroxide on the activity of the membrane bound and the soluilized lipoprotein lipase. Jpn. Clin. J. 47, 837-842
19 Liu, S., Lee, I. M., Ajani, U., Cole, S. R., Buring, J. E. and Manson J. E. (2001) Intake of vegetables rich in carotenoids and risk of coronary heart disease in men; the physician's health study. Int. J. Epidemiol. 30, 130-135   DOI   ScienceOn
20 Mann, J., Mann, J. and Truswel, A. S. (1998) Essentials of Human Nutrition. Oxford University Press, New York
21 Takeuchi, N., Matsumiya, K, Takahashi, Y., Higashino, K. and Tanaka, F. (1984) Thiobarbituric acid reactive substances (TBARS) and lipid metabolism in $\alpha$-tocopherol deficient rats. Exp. Gerontol. 12, 63-68
22 Madar, Z. (1983) Effects of brown rice and soybean dietary fiber on the control of glucose and lipid metabolism in diabetic rats. Am. J. Clin Nutr. 38, 388-393
23 Polidori, M. C., Meccoci, P., Stahl, W., Parente, B., Cecchetti, R., Cherubini, A., Cao, P., Sies, H. and Senin, U. (2000) Plasma levels of lipophilic antioxidants in very old patients with type 2 diabetes. Diabetes Metab. Res. Rev. 16, 15-19   DOI   ScienceOn
24 MacLennan, A. H., Wilson, D. H. and Taylor, R. H. (1996) Prevalence and cost of the alternative medicine in Australia. Lancet 347, 569-57   DOI   ScienceOn
25 Bieri, G, Toliver, J. J. and Catignaani, G. L. (1979) Simultaneous determination of $\alpha$-tocopherol and retionl in plasmia or red blood cells by high pressure liquid chromatography. Am. J. Clin. Nutr. 32, 2143-2149
26 Kang, M. Y., Kim, S., Koh, H. J. and Nam S. H. (2004) Antioxidative activity of germinated specialty Rices. Korean J. Food Sci. Technol. 36, 624-630
27 Gallaher, D. D., Csallany, A. S., Shoeman, D. W. and Olson, J. M. (1993) Diabetes increase excretion of urinary malonaldehyde conjugates in rats. Lipid 28, 663-666   DOI   ScienceOn
28 Upritchard J. E., Sutherland W. H. and Mann, J. I. (2000) Effect of supplementation with tomato juice, vitamin E and vitamin C on LDL oxidation and products of inflammatory activity in type 2 diabetes. Diabetes Care 23, 733-738   DOI   ScienceOn
29 Schraer, C. D., Adler, A. I., Mayer, A. M., Haldeson, K. R. and Trimble, B. A. (1997) Diabetes complications and mortality among Alaska natives: 8 years of observation. Diabetes Care 20, 314-321   DOI   ScienceOn
30 Kim, K. H., Park, S. Z., Koh, H. J. and Hen, M. H. (1992) New mutants for endosperm and embryo characters in rice: two dull endosperm and giant embryo. Proc. of SABRAO Intern. Symp. on the Impacts of Biol. Res. on Agric. Productivity pp. 125-131
31 Wesson, L. G. (1989) Compensatory growth and other growth response of the kidney. Nephron 51, 149-184   DOI   PUBMED
32 Kang, M. Y., Lee, Y. R. and Nam S. H. (2004) Antioxidative and antimutagenic activity of ethanolic extracts from giant embrynoic rices. J. Korean. Soc. Appl. Biol. Chem. 47, 61-66
33 Sathishsekar, D. and Subramanian, S. (2005) Beneficial effects of Momordica charantia in the treatment of STZ-induced diabetes in experimental rats. Biol. Pharm. Bull. 28, 978-983   DOI   ScienceOn
34 Moon, S. J. (1996) Nutritional problems of Korean. Kor. J. Nutr. 29, 371-380
35 Wolff, S. P., Jiang, Z. Y. and Hunt, J. V. (1991) Protein glycation and oxidative stress in diabetes mellitus and aging. Free Radic. Biol. Med. 10, 339-352   DOI   ScienceOn
36 Lee, D. M., Hoffman, W. H., Carl, G. F. and Cornwell, P. E. (2002) Lipid peroxidation and antioxidant vitamin prior to, during, and after correction of diabetic ketoacidosis. J. Diabetes Complications 16, 294-300   DOI   ScienceOn
37 Sato, Y., Hotta, N., Sukamoto, N., Natenoka, S., Ohishi, N. and Yagi, N. (1979) Lipid peroxide level in plasma of diabetic patients. Biochem. Med. 21, 104-110   DOI   ScienceOn
38 Paglia, D. E. and Valentine, W. N. (1967) Studies of the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med. 70, 158-169
39 Ha, A. W. and Kim, H. M. (1999) The Study of lipid-peroxidation, antioxidant enzymes, and the antioxidant vitamin in NIDDM patients with microvascular-diabetic complications. Korean J. Nutr. 21, 17-23