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In vitro Biological Activity Assay of Ethanol Extract of Radish  

Jung, Min-Suk (Department of Food and Biotechnology and Department of Innovative Industrial Technology, Hoseo University)
Lee, Gun-Soon (Department of Rural Living Science, Korea National Agricultural College)
Chae, Hee-Jeong (Department of Food and Biotechnology and Department of Innovative Industrial Technology, Hoseo University)
Publication Information
Applied Biological Chemistry / v.47, no.1, 2004 , pp. 67-71 More about this Journal
Abstract
In vitro biological activities of ethanol extract of radish including whitening, hangover removal, antimicrobial and antioxidant activities were analyzed. For whitening activity assay, tyrosinase inhibition rate was measured as $IC_{50}$ (50% inhibitory concentration). The $IC_{50}$ values of radish trunk and root extracts were estimated as 0,9 mg/ml and 2.1 mg/ml, respectively. Radish trunk extract showed 2.5-fold tyrosinase inhibition activity of radish root extract, however, there was no significant difference according to radish species. By alcohol dehydrogenase (ADH) activity assay as a hangover removal activity assay, radish trunk extract (2.5 mg/ml) and root extracts (8 mg/ml) showed ]50% activation of ADH. TBA values of radish trunk and root extracts (1% of each) were 43-61 % level of ${\alpha}-tochoperol$ (2.2%). From the analysis of in vitro biological activities of radish, it was suggested that radish could be used in functional food or cosmetics containing hangover removal, whitening and antioxidant activities.
Keywords
radish; whitening activity; hangover removal; antioxidant activity;
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