Browse > Article

Cytotoxic and Antibacterial Activities of Sanguisorbae officinalis L.  

Lee, Soon-Ae (Department of Cosmetic Engineering, Daegu Haany University)
Son, Jun-Ho (Department of Cosmetic Engineering, Daegu Haany University)
Kwak, Jae-Hoon (Department of Cosmetic Engineering, Daegu Haany University)
Park, Jung-Mi (Department of Cosmetic Engineering, Daegu Haany University)
Lee, Jin-Young (Department of Cosmetic Engineering, Daegu Haany University)
An, Bong-Jeun (Department of Cosmetic Engineering, Daegu Haany University)
Publication Information
Applied Biological Chemistry / v.47, no.1, 2004 , pp. 141-145 More about this Journal
Abstract
The cytotoxic and antibacterial activities of Sanguisorbae officinalis L., which is known as a major tannin source, were investigated to check the possible use of natural nutraceutics or cosmetics. The S. officinalis inhibited cancer cell growth in a dose-dependant manner. Also, the clear zone against various bacteria such as Staphylococcus aureus, S. epidermidis, E. coli were evident at 0.5 and 1 mg/disc. When the concentrations were 500 and 1,000 ppm, growth of all aerobic bacteria increased at early stage but decrease afterward. The results indicated that S. officinalis had the anti-skin cancer activity as well as antibacterial activity against skin-related bacteria.
Keywords
Sanguisorbae officinalis; cytotoxic activity; MTT; antibacterial activity;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Yoshihiro, M., Masato, R, Akihito, Y, Yutaka, S., Shigenon, F. and Hiroshi, S. (2001) Tiiterpene glycosides from the roots Saneuisorba officinats. Phytochemistry 57, 773-779   DOI   ScienceOn
2 Chung, K. S., Yoon, K. D., Kwon, D. J., Hong, S. S and Choi, S. Y. (1997) Cytotoxicity testing of fermented soybean products with various tumour cells using MTT assay. Kor. J. Appl. Microbiol Biotechnol. 25, 477-482
3 Kang, S. K. (1995) Isolation and antimicrobial activity of antimicrobial substance obtained from leaf mustard. J. Kor. Soc. Food Nutr. 24, 695-701
4 Yokozawa, T., Chen, C. P., Tanaka, T. and Kitani, K. (2000) A study on the nitric oxide production-suppressing activity of Sanguisorbae Radix components. Biol. Pharm. Bull. 23, 717-722
5 Bastow, K. R, Bori, I. D., Fukushima, Y, Kashiwada, Y, Tanaka, T., Nonaka, G., Nishioka, I. and Lee, K.-H. (1993) Inhibition of DNA topoisomerases by sanguiin H-6, a cytotoxic dimeric ellagitannin from Sanguisorba officinalis. Planta Med. 59, 240-245   DOI   ScienceOn
6 Park, J. G., Kramer, B. S., Steinber, S. M., Carmichael, J., Collins, J. M., Minna, J. D. and Gazdar, A. F. (1987) Chemosensitivity testing of human colorectal carcinoma cell lines using a tetrazolium-based colorimetnc assay. Cancer Res. 47, 5875-5879
7 Kokoska, L., Polesny, Z., Raba, V., Nepovim, A. and Vanek, T. (2002) Screening of some Siberian medicinal plants for antimicrobial activity. J. Ethnophamacol. 82, 51-53   DOI   ScienceOn
8 Nonaka. G., Tanaka. T. and Nishioka, I. (1982) Taimins and related compounds. Part 3. A new phenolic acid, sanguisorbic acid dilactone and three new ellagitanins, sanguiins H-l, H-2, and H-3, from Sanguisorba officinals. J. Chem. Soc. Perkin Translation 4, 1067-1777
9 Kim, H. K., Chun, H. J. and Han, Y. S. (1998) Screening of antimicrobial activity of the dandelion extract. Kor. J. Soc, Food Sci. 14, 144-147
10 Cheng, D.-L. and Cao, X.-P. (1992) Pomolic acid derivatives from the root of Saneuisorba officinalis. Planta Med. 59, 240-245   DOI   ScienceOn
11 Reher, G. and Budesinsky, M. (1992) Thterpenoids from plants of the aneuissorbeae. Phytochemistry 31, 3909-3914   DOI   ScienceOn
12 Elena, A. G., Petnchenko, V. M., Solodnikov, S. U., Suhinina, T. V, Kline, M. A., Glenn, C., Chi, N. and Howard, M. (2002) Anticancer and antithrombin activity of Russian plants. J. Ethnophamacol. 81, 337-342   DOI   ScienceOn
13 National college of oriental medicine herbology professor association. (1994) Herbology, Yonglim Press, Seoul, pp. 392-393
14 Kim, E. J., Jung, S. W., Choi, K. P. and Ham, S. S. (1998) Cytotoxic effect of the pine needle extracts. Kor. J. Food Sci. Technol. 30, 213-217
15 Biemond, P., Swaak, A. J., van Eijk, H. G. and Koster, J. F. (1988) Superoxide dependent iron release from fenitin in inflammatory diseases. Free Radic. Biol, Med. 4, 185-198   DOI   ScienceOn
16 Tanaka. T., Nonaka, G. and Nishioka, I. (1983) 7-0-Ga11oy1-(+)-catechm and 3-0-ga11oy1procyamdin B-3 from Sanguisorba officinalis. Phytochemistry 22, 2575-2578   DOI   ScienceOn
17 Charmichael, J., DearaS, W. G., Gazdar, A. F, Minna, J. D. and Michell, J. B. (1987) Evaluation of a tetrazolium based semiautomated colorimetric assay, assissment of chemosensitivity testing. Cancer Res. 47, 936-942