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http://dx.doi.org/10.9718/JBER.2019.40.5.158

Clinical Safety Evaluation of Interbody Fusion Cage Based on Tunable Elastic Modulus of the Cellular Structure According to the Geometrical Variables  

Kim, SeongJin (Department of Biomedical Materials, Konyang University)
Lee, YongKyung (Department of Mechanical Engineering, Sejong University)
Choi, Jaehyuck (Department of Mechanical Engineering, Sejong University)
Hong, YoungKi (Department of Biomedical Materials, Konyang University)
Kim, JungSung (Central R&D center, CORENTEC CO., LTD)
Publication Information
Journal of Biomedical Engineering Research / v.40, no.5, 2019 , pp. 158-164 More about this Journal
Abstract
The interbody fusion cage used to replace the degenerative intervertebral disc is largely composed of titanium-based biomaterials and biopolymer materials such as PEEK. Titanium is characterized by osseointergration and biocompatibility, but it is posed that the phenomenon such as subsidence can occur due to high elastic modulus versus bone. On the other hand, PEEK can control the elastic modulus in a similar to bone, but there is a problem that the osseointegration is limited. The purpose of this study was to implement titanium material's stiffness similar to that of bone by applying cellular structure, which is able to change the stiffness. For this purpose, the cellular structure A (BD, Body Diagonal Shape) and structure B (QP, Quadral Pod Shape) with porosity of 50%, 60%, 70% were proposed and the reinforcement structure was suggested for efficient strength reinforcement and the stiffness of each model was evaluated. As a result, the stiffness was reduced by 69~93% compared with Ti6Al4V ELI material, and the stiffness most similar to cortical bone is calculated with the deviation of about 12% in the BD model with 60% porosity. In this study, the interbody fusion cage made of Ti6Al4V ELI material with stiffness similar to cortical bone was implementing by applying cellular structure. Through this, it is considered that the limitation of the metal biomaterial by the high elastic modulus may be alleviated.
Keywords
Cellular structure; Porosity; Tunable elastic modulus; Interbody fusion cage;
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