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http://dx.doi.org/10.9718/JBER.2018.39.5.175

Effects of Hyperbaric Oxygen Intervention on Alcohol-Induced Oxidative Stress and Hangover in Hyperbaric Oxygen Chamber  

Kwon, Hyeok Chan (Department of Biomedical Engineering, Graduate School, Konyang University)
Park, Soon Won (Department of Biomedical Engineering, Graduate School, Konyang University)
Cho, Hyun Jeong (Department of Biomedical Laboratory Science, Konyang University)
Kang, Ji Hyun (Department of Family Medicine, Konyang University Hospital)
Lee, Hyun Ju (Department of Physical Therapy, Konyang University)
Tae, Ki Sik (Department of Biomedical Engineering, Graduate School, Konyang University)
Publication Information
Journal of Biomedical Engineering Research / v.39, no.5, 2018 , pp. 175-182 More about this Journal
Abstract
The purpose of this study is to evaluate the reliability and effectiveness of hyperbaric oxygen chamber on alcohol-induced oxidative stress and hangover. In order to evaluate them, 20 healthy adults were tested for blood and hangover stress tests. When an exponential change was examined after 3 interventions (hangover drink, hyperbaric oxygen chamber, and normal chamber as placebo effect) of 1 hour, the heart rate of subjects experiencing a hyperbaric oxygen chamber showed a statistically significant decrease (p < 0.001). The tests of blood alcohol concentration (BAC) as for exquisite hematology analysis, glucose, creatinine, and AST (aspartate aminotransferase) as well as ALT (alanine aminotransferase) used as liver-damage indicator show that the hyperbaric chamber has the effective effect. In the test of lactic acid, CRP (c-reactive protein), cortisol, and creatinine, the hyperbaric chamber shows much more excellent effect than the hangover drink and normal chamber as control groups. Further studies on hyperbaric oxygen chamber intervention including this study could be very helpful for improving lives of both the patients and healthy people.
Keywords
Hyperbaric oxygen chamber; Blood test; Stress; Hangover; Blood alcohol concentration;
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