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http://dx.doi.org/10.9718/JBER.2013.34.4.177

Modulation in Action Potentials of Rat Hippocampal Neurons Measured on Multi-Channel Electrodes During Ultrasound Stimulation  

Han, H.S. (Department of Biomedical Engineering, Kyung Hee University)
Jeon, H.J. (Department of Biomedical Engineering, Kyung Hee University)
Hwang, S.Y. (Department of Electronics Engineering, College of Engineering, Ewha Womans University)
Lee, Y.N. (Department of Electronics Engineering, College of Engineering, Ewha Womans University)
Byun, K.M. (Department of Biomedical Engineering, Kyung Hee University)
Jun, S.B. (Department of Electronics Engineering, College of Engineering, Ewha Womans University)
Kim, T.S. (Department of Biomedical Engineering, Kyung Hee University)
Publication Information
Journal of Biomedical Engineering Research / v.34, no.4, 2013 , pp. 177-181 More about this Journal
Abstract
It is known that ultrasound affects action potentials in neurons, but the underlying principles of ultrasonic neural stimulation are not clearly elucidated yet. In this study, we measured the action potentials of rat hippocampal neurons cultured on multi-electrode arrays during ultrasound stimulation. From most of electrodes, it was observed that the ultrasound stimulation increased the frequencies of action potentials (i.e., spikes) during ultrasound stimulation.
Keywords
Transcranial Ultrasound Stimulation; Neuromodulation; Multi-Channel System; Action Potential; Hippocampal Neurons;
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