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http://dx.doi.org/10.9718/JBER.2010.31.6.472

Evaluation of Effective Cartilage Reshaping using Nd:YAG laser (${\lambda}$ = 1444 nm)  

Yoon, Jin-Hee (Dept. of Biomedical Engineering, College of Medical Science, Catholic University of Daegu)
Youn, Jong-In (Dept. of Biomedical Engineering, College of Medical Science, Catholic University of Daegu)
Publication Information
Journal of Biomedical Engineering Research / v.31, no.6, 2010 , pp. 472-480 More about this Journal
Abstract
Mechanically deformed cartilage undergoes a temperature dependent phase transformation resulting in reshaping of cartilage. Laser-assisted cartilage reshaping (LCR) is recently introduced to recreate the underlying cartilage framework in structures such as ear, larynx, trachea, and nose. However, this procedure has not been fully supported by confirmed efficacy because of the lack of scientific research and its safety issues. The purpose of this study is to evaluate current laser sources to determine optimal laser wavelength for LCR using mathematical simulations and investigate optical, thermo-mechanical, and backscattering properties of cartilage after laser irradiation. The results showed that 1444 nm wavelength was effective for reshaping of cartilage with minimal thermal damage in the surrounded tissues by monte carlo simulations. Analysis of bend angle changes, thermo-mechanical characteristics, and backscattered properties may be useful to better identify the biophysical transformation responsible for stress relaxation in cartilage and develop an optical feedback control methodologies.
Keywords
Nd:YAG laser; cartilage reshaping; Monte carlo simulation; bend angle; road cell; backscattering;
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1 B. J. F. Wong, T. E. Milner, B. Anvari, "Measurement of Radiometric Surface Temperature and Integrated Back-Scattered Light Intensity During Feedback Controlled Laser-Assisted Cartilage Reshaping," Lasers in Med. Sci., vol. 13, pp. 66-72, 1998.   DOI   ScienceOn
2 B. J. F. Wong, T. E. Milner, H. K. Kim, "Critical Temperature Transitions in Laser Mediated Cartilage Reshaping," Proceedings SPIE, vol. 3425, pp. 161-172, 1998.
3 B. J. F. Wong, T. E. Milner, B. Anvari, "Thermo-Optical Response of Cartilage During Feedback Controlled Laser- Assisted Reshaping," Proceedings SPIE, vol. 2970, pp. 380-391, 1997.
4 임현수, 구철희, "Monte Carlo 시뮬레이션을 이용한 생체조직내의 광선량 측정", J. Biomed. Eng. Res., vol. 20, no. 2, 199-204, 1999.
5 N. V. Bagratashvili, A. P. Sviridov, E. N. Sobol, A. I. Omel'chenko, S. I. Tsypina, V. P. Gapontsev, I. E. Samartsev, F. Feldchtein, R. V. Kuranov, "Kinetics of water transfer and stress relaxation in cartilage heated with 1.56 ${\mu}$ fiber laser," Laser-Tissue interaction XI : Photochemical, photothermal, and photomechanical, Bellingham, USA: SPIE; 2000, vol. 3914, pp. 102-107.
6 E. N. Sobol, I. M. Ovchinnikov, V. M. Svishtushkin, N. V. Bagratashvili, A. Sviridov, A. Omel'chenko, N. N. Vorobjeva, A. B. Shekhter, "Cartilage reshaping under non-ablative laser radiation: Research and clinical applications in ENT," Lasers in Surgery: Advanced characterization, therapeutics, and systems, 12th edn, Bellingham, USA: SPIE, 2002, vol. 4609, pp. 331-336.
7 I. S. Choi, Y. S. Chae, A. Zemek, and D. E. Protsenko, "Viability of Human Septal Cartilage After $1.45{\mu}$ Diode Laser Irradiation," Laser Surg Med., vol. 40, pp. 562-569, 2008.   DOI
8 B. J. F. Wong, T. E. Milner, H. K. Kim, S. A. Telenkov, C. F. Chew, E. N. Sobol, and J. S. Nelson, "Characterization of Temperature-Dependent Biophysical Properties During Laser Mediated Cartilage Reshaping," IEEE J Sel Top Quantum Electron, vol. 5, no. 4, pp. 1095-1102, 1999.   DOI   ScienceOn
9 H. Fry, and W. V. Robertson, "Interlocked stresses in cartilage," Nature, vol. 215, no. 5096, pp. 53-54, 1967.   DOI   ScienceOn
10 B. J. F. Wong, T. E. Milner, H. H. Kim, J. S. Nelson, E. N. Sobol, "Stress Relaxation of Porcine Septal Cartilage During $Nd:YAG\;({\lambda}=1.32\;{\mu}m)$ Laser Irradiation : Mechanical, Optical, and Thermal Response," J. of Bioded. Opt., vol. 3, no. 4, pp. 409-414, 1998.   DOI   ScienceOn
11 D. S. Gray, J. A. Kimball, and B. J. Wong, "Shape retention in porcine septal cartilage following $Nd:YAG\;({\lambda}=1.32\;{\mu}m)$ laser-mediated reshaping," Lasers Surg Med., vol. 29, no. 2, pp. 106-164, 2001.   DOI   ScienceOn
12 M. A. Trelles, S. R. Mordon, "Correction of ear malformations by laser-assisted cartilage reshaping(LACR)," Lasers Surg Med, vol. 38, no. 7, pp. 659-668, 2006.   DOI   ScienceOn
13 L. Wang, S. L. Jacques, and L. Zheng, "Monte Carlo Modeling of light transport in multi-layered tissues," Computer methods and programs in biomedicine., pp. 131-146, 1995.
14 X. J. Wang, T. E. Milner, M. C. Chang, and J. S. Nelson, "Group refractive index measurement of dry and hydrated type I collagen films using optical low-coherence reflectometry," J Biomed Opt., vol. 1, pp. 212-216, 1996.   DOI   ScienceOn
15 L. P. Gartner, and J. L. Hiatt, "Cartilage and bone," In: Gartner LP, Hiatt HL editors. Color textbook of histology. 3rd ed, Philadelphia, USA: Saunders elsevir, 2007, pp. 131-187.
16 E. N. Sobol, V. Bagratashvili, A. Sviridov, A. Omel'chenko, M. Kitai, N. Jones, V. Zenger, A. Nasedkin, M. Isaev, and A. Shechter. "Study of cartilage reshaping with holmum laser," Rroc SPIE, vol. 2623, pp. 544-547, 1996.
17 E. Helidonis, E. Sobol, G. Kavvalos, J. Bizakis, P. Christodoulou, G. Velegrakis, J. Segas, V. Bagratashvili, "Laser shaping of composite cartilage grafts," Am J Otolaryngol., vol. 14, no. 6, pp. 410-412, 1993.   DOI   ScienceOn
18 E. Sobol, A. Sviridov, A. Omel'chenko, V. Bagratashvili, M. Kitai, S. E. Harding, N. Jones, K. Jumel, M. Merting, W. Pompe, Y. Ovchinnikov, and V. Svistushkin, "Laser reshaping of cartilage," Biotechnol Genet Eng Rev., vol. 17, pp. 553-578, 2000.   DOI   ScienceOn
19 S. H. Diaz-Valdes, G. Aguilar, R. Basu, E. J. Lavernia, B. J. Wong, "Modeling the thermal response of porcine cartilage to laser irradiation," Laser-Tissue interaction XI II : Photochemical, photothermal, and photomechanical, CA, USA: San Jose, 2002, pp. 47-56.
20 Y. Chae, G. Aguilar, E. J. Lavernia, B. J. Wong, "Characterization of temperature dependent mechanical behavior of cartilage," Lasers Surg Med, vol. 32, pp. 271-278, 2003.   DOI   ScienceOn
21 J. I. Youn, S. A. Telenkov, E. Kim, N. C. Bhavaraju, B. J. Wong, J. W. Valvano, "Optical and thermal properties of nasal septal cartilage," Lasers Surg Med., vol. 27, no. 2, pp. 119-128, 2000.   DOI   ScienceOn
22 Y. Ovchinnikov, E. Sobol, V. Svistushkin, A. Shekhter, V. Bagratashvili, and A. Sviridov, "Laser septochondrocorrection," Arch Racial Plast Surg., vol. 4, pp. 180-185, 2002.   DOI
23 A. S. E. Sviridov, N. Jones, and J. Lowe, "The effect of holmium laser radiation on stress, temperature and structure of cartilage," Lasers Med Sci., vol. 13, pp. 73-7, 1998.   DOI   ScienceOn
24 S. Mordon, T. Wang, L. Fleurisse, and C. Creusy. "Laser cartilage reshaping in an in vivo rabbit model using a 1.54 microm Er:Glass laser," Lasers Surg Med., vol. 34, pp. 315-22, 2004.   DOI   ScienceOn
25 M. Ayhan, O. Deren, M. Gorgu, B. Erdogan, A. Dursun, "Cartilage shaping with the Er:YAG laser: An in vivo experimental study," Ann Plast Surg., vol. 49, no. 5, pp. 527-531, 2002.   DOI   ScienceOn
26 D. S. Gray, J. A. Kimball, and B. J. F. Wong, "Shape Retention in Porcine-Septal Cartilage Following $Nd:YAG({\lambda}=1.32{\mu}m)$ Laser-Mediated Reshaping," Lasers Surg Med., vol. 29, pp. 160-164, 2001.   DOI   ScienceOn