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http://dx.doi.org/10.9718/JBER.2009.30.4.311

Automatic Control System Design and Implementation for a Miniaturized DNA Extraction System using Magnetic Beads  

Kim, S. (Department of Biomedical Engineering, College of Medicine, Seoul National University)
Kim, J.D. (Department of Computer Engineering, Hallym University)
Kim, H.C. (Department of Biomedical Engineering, College of Medicine, Seoul National University)
Kim, J. (Biomedlab Co., Ltd.)
Publication Information
Journal of Biomedical Engineering Research / v.30, no.4, 2009 , pp. 311-317 More about this Journal
Abstract
An automatic control system is proposed and implemented for a miniaturized DNA extraction system using magnetic bead. A host-local system is employed for the accommodation of the graphical user interface and the basic control function. The functional partitioning into the local and the host system is discussed. The control functions are classified and formalized for the flexible control scenario, which is the input of the proposed system. As the proposed scenario is consists of the sequence of the user-centric actions, the user goal can be easily programmed and modified. The DNA extraction performance of the implemented system was compared with the existing silica-membrane-based method, resulting in the comparable concentration and purity of the extracted DNA. The proposed system is currently being utilized for the development of the DNA extraction system only changing scenario, without any alteration of the system.
Keywords
DNA extraction; magnetic bead; host-local system; functional partitioning; scenario;
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