Browse > Article
http://dx.doi.org/10.9718/JBER.2008.29.2.089

Medical Applications of Near Infrared Spectroscopy and Diffuse Optical Imaging (Review)  

Lee, Seung-Duk (Department of Biomedical Engineering, Yonsei University)
Kwon, Ki-Won (Department of Biomedical Engineering, Yonsei University)
Koh, Dal-Kwon (Department of Biomedical Engineering, Yonsei University)
Kim, Beop-Min (Department of Biomedical Engineering, Yonsei University)
Publication Information
Journal of Biomedical Engineering Research / v.29, no.2, 2008 , pp. 89-98 More about this Journal
Abstract
NIRS (Near-infrared Spectroscopy) and DOI (Diffuse Optical Imaging) are relatively new, non-invasive, and non-ionizing methods that measure or image optical properties (Scattering and Absorption Coefficient) and physiological properties (Water Fraction, concentration of Oxy-, Deoxy-Hemoglobin, Cytochrome Oxidase, etc) of biological tissues. In this paper, three different types of NIRS systems, mathematical modeling, and reconstruction algorithms are described. Also, recent applications such as functional brain imaging, optical mammography, NIRS based BMI (Brain-Machine Interface), and small animal study are reviewed.
Keywords
near-infrared spectroscopy (NIRS); hemodynamic response; neuroimaging;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Eiju Watanabe etal., 'Noninvasive cerebral blood volume measurement during seizures using multichannel near infrared spectroscopic topography', Journal of Biomedical Optics, vol. 5, no. 3, pp. 287-290, 2000   DOI   ScienceOn
2 Alper Corlu et al. 'Three dimensional in vivo fluorescence diffuse optical tomography of breast cancer in humans', Optics Express, vol. 15, no. 11, pp.6696-6716, 2007   DOI
3 Vasilis Ntziachristos et aI., 'Mkl-guided diffuse optical spectroscopy of malignant and benign breast lesions', Neoplasia, vol. 4, no.4, pp.347-354, 2002   DOI   ScienceOn
4 T. J. Huppert et al., 'A temporal comparison of BOLD, ASL, and NIRS hemodynamic responses to motor stimuli in adult humans', Neuroimage, vol. 29, pp. 368-382, 2006   DOI   ScienceOn
5 Vlad Toronov et aI., 'Near infrared study of fluctuations in cerebral hemodynamics during rest and motor stimulation: temporal analysis and spatial mapping', Medical Physics, vol. 24, no.4, pp.801-815, 2000
6 Maria Angela Franceschini et aI., 'Diffuse optical imaging ofthe whole head', Journal of Biomedical Optics, vol. 11, no. 5, 054007, 2006   DOI   ScienceOn
7 Hellmuth Obrig et al., 'Near-infrared spectroscopy: does it function in functional activation studies of the adult brain?', International Journal of Psychophysiology, vol. 35, pp. 125-142, 2000   DOI   ScienceOn
8 A. H. Hielscher et al., 'Near-infrared diffuse optical tomography', Disease Markers, vol. 18, pp. 313-337, 2002   DOI   PUBMED
9 David A. Boas et al., 'Imaging the body with diffuse optical tomography', IEEE Signal Processing Magazine, vol. 18, no. 6, pp. 57-75, 2001   DOI   ScienceOn
10 Martin M. Tisdall et al, 'Near-infrared spectroscopic quantification of changes in the concentration of oxidized cytochrome c oxidase in the healthy human brain during hypoxemia', Journal of Biomedical Optics, vol. 12, no. 2, 023002, 2007
11 Minah Suh et al., 'Neurovascular coupling and oximetry during epileptic events', Molecular Neurobiology, vol. 33, pp. 181-197, 2006   DOI   ScienceOn
12 Amo Villringer et al., 'Non-invasive optical spectroscopy and imaging of human brain function', Trends in Neurosciences, vol. 20, no. 10, pp. 435-442, 1997   DOI   ScienceOn
13 Vasilis Ntziachristos et aI., 'Concurrent MRI and diffuse optical tomography of beast after indocyanine green enhancement', Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 6, pp. 2767-2772, 1999   DOI   ScienceOn
14 T. Austin et al, 'Three dimensional optical imaging of blood volume and oxygenation in the neonantal brain', Neuroimage, vol. 31, pp. 1426-1433, 2006   DOI   ScienceOn
15 Regine Choe et al. 'Diffuse optical tomography of breast cancer during neoadjuvant chemotherapy: A case study with comparison to MRI', Medical Physics, vol. 32, no. 4, pp.1128-1139, 2005   DOI   ScienceOn
16 Dinesh G. Nair, 'About being BOLD', Brain Research Reviews, vol. 50, pp. 229-243, 2005   DOI
17 Gregory Boverman et aI., 'Spatio-temporal imaging of the hemoglobin in the compressed breast with diffuse optical tomography', Physics in Medicine and Biology, vol. 52, pp. 3619-3641, 2007   DOI   ScienceOn
18 Chao Zhou et al., 'Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy', Journal of Biomedical Optics, vol. 12, no. 5, 051903, 2007   DOI   ScienceOn
19 Joseph P. Culver et al., 'Diffuse optical tomography of cerebral blood flow, oxygenation, and metabolism in rat during focal ischemia', Journal of Cerebral Blood Flow and Metabolism, vol. 23, pp.911-924, 2003   DOI
20 Shirely M. Coyle et al., 'BCI-computer interface using a simplified functional near-infrared spectroscopy system', Journal of Neural Engineering, vol. 4, pp. 219-226, 2007   DOI   ScienceOn
21 F. Crespi et aI., 'Near infrared oxymeter biosensor prototype for non-invasive in vivo analysis of rat brain oxygenation: effects of drugs of abuse', Journal of Optics A, vol. 8, pp. s528-s534, 2006   DOI   ScienceOn
22 Varley V. Tuchin, 'Tissue Optics: light scattering methods and instruments for Medical Diagnosis', SPIE Press, 1997
23 Scott A. Huettel et al., 'Functional magnetic resonance imaging', Sinauer, pp.127-129, 2003
24 Zhen Yuan et al., 'Three-dimensional diffuse optical tomography of osteoarthritis: initial results in the finger joints', Journal of Biomedical Optics, vol. 12, no. 3, 034001, 2007   DOI   ScienceOn
25 Turgut Durduran et al. 'Diffuse optical measurement of blood flow in breast tumors', Optics Letters, vol. 30, no. 21, pp. 2915 -2917, 2005   DOI   ScienceOn
26 Yu Chen et al., 'Correlation between near-infrared spectroscopy and magnetic resonance imaging of rat brain oxygenation modulation', Physics in Medicine and Biology, vol. 48, pp. 417-427, 2003   DOI   ScienceOn
27 Ron D. Frostig, 'In vivo optical imaging of brain function', CRC press, 2002
28 Bruce A. Crookes et al., 'Can near-infrared spectroscopy identify the severity of shock in trauma patients?', Journal of Trauma, vol. 58, pp. 806-816, 2005   DOI
29 Jacques Creteur et aI., 'The prognostic value of muscle StO2 in septic patients', Intensive Care Medicine, vol. 33, pp. 1549-1556, 2007   DOI   ScienceOn
30 Maria Angela Franceschini et al., 'Noninvasive measurement of neural activity with near-infrared optical imaging', Neuroimage, vol. 21, pp. 372-386, 2004   DOI   ScienceOn
31 H. Bortfeld et al., 'Assessing infants' cortical response to speech using near-infrared spectroscopy', Neuroimage, vol. 34, no. 1, pp. 407-415, 2007   DOI   ScienceOn
32 Gentaro Taga et al, 'Spontaneous oscillation of oxy-hemoglobin changes with a phase difference throughout occipital cortex of newborn infants observed using non-invasive optical topography', Neuroscience Letters, vol. 282, pp. 101-104, 2000   DOI   ScienceOn
33 A. Y. Bluestone et al., 'Three-dimensional optical tomographic brain imaging in small animals, part 1: hypercapnia', Journal of Biomedical Optics, vol. 9, no. 5, pp. 1046-1062, 2004   DOI   ScienceOn
34 Gary Strangman et al., 'Non-invasive neuroimaging using nearinfrared light', Biological Psychiatry, vol. 52, pp. 679-693, 2002   DOI   ScienceOn
35 Colin S. Hawco et al., 'BOLD changes occur prior to epileptic spikes seen scalp EEG', Neuroimage, vol. 35, pp. 1450-1458, 2007   DOI   ScienceOn
36 Peter Rolfe, 'In vivo near-infrared spectroscopy', Annual Review of Biomedical Engineering, vol. 2, pp. 715-754, 2000   DOI   ScienceOn
37 S. Fantini et al., 'Semi-infinite geometry boundary problem for light migration in highly scattering media: a frequency domain study in the diffusion approximation', Journal of the Optical Society of America B-Optical Physics, vol. 11, pp. 2128-2138, 1994   DOI   ScienceOn
38 Frontal Hatakenaka et al. 'Frontal regions involved in learning of motor skill- a functional NIRS study', Neuroimage, vol. 34, pp. 109-116, 2007   DOI   ScienceOn
39 Costantino Iadecola et al., 'Glial regulation of the cerebral microvasculature', Nature Neuroscience, vol. 10, no. 11, pp. 1369-1376, 2007   DOI   ScienceOn
40 Andrew M. Siegel et al., 'Temporal comparison of functional brain imaging with diffuse optical tomography and fMRI during rat forepaw stimulation', Physics in Medicine and Biology, vol. 48, pp.1391-1403, 2003   DOI   ScienceOn
41 Joseph P. Culver et al., 'Evidence that cerebral blood volume can provide brain activation maps with better spatial resolution than deoxygenated hemoglobin', Neuroimage, vol. 27, pp. 947-959, 2005   DOI   ScienceOn
42 N. Roche-Labarbe et aI., 'Coupled oxygenation measured by NlRS and intermittent cerebral activation on EEG in premature infants', Neuroimage, vol. 36, pp. 718-727, 2007   DOI   ScienceOn
43 Ranganatha Sitaram et al., 'Temporal classification of multichannel nearinfra red spectroscopy signals of motor imagery for developing a brain-computer interface', Neuroimage, vol. 34, pp. 1416-1427, 2007   DOI   ScienceOn
44 Quan Zang et al., 'Coregistered tomographic x-ray and optical breast imaging: initial results', Journal of Biomedical Optics, vol. 10, no. 2, 024033, 2005   DOI   ScienceOn
45 D. T. Delpy et al., 'Estimation of optical pathlength through tissue from direct time of flight measurement', Physics in Medicine and Biology, vol. 33 no. 12, pp. 1433-1442, 1988   DOI   ScienceOn
46 Katharina Buchheim et al., 'Decrease in haemoglobin oxygenation during absence seizures in adult humans', Neuroscience Letters, vol. 354, pp. 119-122, 2004   DOI   ScienceOn
47 Christoph H. Schmitz et al., 'Dynamic studies of small animals with a four-color diffuse optical tomography imager', Review of Scientific Instruments, vol. 76, 094302, 2005   DOI   ScienceOn
48 Thomas Misgeld et al., 'In vivo imaging of the diseased nervous system', Nature Reviews Neuroscience, vol. 7, pp. 449-463, 2006   DOI   ScienceOn
49 Stefan A. Carp et al., 'Comparison-induced changes in the physiological state of the breast as observed through frequency domain photon migration measurements', Journal of Biomedical Optics, vol. 11, no. 6, 064016, 2006   DOI   ScienceOn
50 Hanli Liu et aI., 'Near infrared and visible spectroscopic measurements to detect changes in light scattering and hemoglobin oxygen saturation from rat spinal cord during peripheral stimulation', Neuroimage, vol. 40, pp. 217-227, 2008   DOI   ScienceOn
51 Lihong Wang et al., 'MCML-Monte Carlo modeling of light transport in multi-layered tissues', Computer Methods and Programs in Biomedicine, vol. 47, pp. 131-146, 1995   DOI   ScienceOn
52 Franz Jobsis, 'Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters', Science, vol. 198, no. 4323, pp. 1264-1267, 1977   DOI