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http://dx.doi.org/10.9718/JBER.2007.28.5.684

Analysis on the Blood F1ow, Pressure and Pulsatility of a Dual Pulsatile Extracorporeal Life Support  

Choi, Seong-Wook (Program of Mechanics and Biomedical Engineering. College of Engineering, Kangwon National University)
Min, Byoung-Goo (Department of Biomedical Engineering, College of Medicine, Seoul National University)
Publication Information
Journal of Biomedical Engineering Research / v.28, no.5, 2007 , pp. 684-693 More about this Journal
Abstract
Previous trials for development of a pulsatile-Extracorporeal Life Support had some defects such as insufficient blood flow, high pressure at its membrane oxygenator and the high risk of blood cell damage. To solve those problems of previous pulsatile-ECLSs, we suggest dual pulsatile blood pump structure for the new pulsatile-ECLS. Two pulsatile pumps areconnected in a parallel manner and this new structure raises the inflow capacity and efficiency and it decreases the high blood pressure at membrane oxygenator. In in-vitro experiments, The Energy Equivalent Pressure Increment(EEP inc.) was 10%, and it showed that its pulsatilty was $5{\sim}10$ times higher than other commercial ECLS In in-vivo experiments, we had applied a new pulsatile-ECLS to 30 Kg pigs and a new pulsatile-ECLS couldsupport high blood flow and pulsatility above 2 L/min, 10% EEP inc.
Keywords
pulsatile; extracorporeal life support; energy equivalent pressure increment(EEP inc.);
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