Browse > Article
http://dx.doi.org/10.9718/JBER.2007.28.4.477

The Influence of Eye Movement for Acquiring BOLD Signal in V1 : A Study of Simultaneous Measurement of EOG and fMRI  

Chung, Jun-Young (Neuroscience Research Institute, Gachon University of Medicine and Science)
Yoon, Hyo-Woon (Neuroscience Research Institute, Gachon University of Medicine and Science)
Kim, Young-Bo (Neuroscience Research Institute, Gachon University of Medicine and Science)
Park, Hyun-Wook (Department of Electrical Engineering, Korea Advanced Institute of Science and Technology)
Publication Information
Journal of Biomedical Engineering Research / v.28, no.4, 2007 , pp. 477-483 More about this Journal
Abstract
We have measured EOG and fMRI simultaneously to investigate whether eye movement (blinking mechanism) might influence functional magnetic resonance imaging (fMRI) signal response in the primary visual cortex. $T2^*-weighted$ Echo-Planar Imaging (EPI) with concurrent electrooculogram (EOG) was acquired in four subjects while they viewed a fixation point and a checkerboard with a flickering rate of 8Hz. With the help of EOG information we divided the experimental blocks into two different conditions: fixation and moving eye. We have compared the fMRI data of these two conditions. Our results have shown that there is no difference between these two conditions. This might suggest that eye blinking does not affect BOLD signal changes in the primary visual cortex. This means further that eye blinking can be ignored in data processing.
Keywords
EOG and fMRI simultaneous measurement; eye blinking;
Citations & Related Records
연도 인용수 순위
  • Reference
1 T. Ernst and J. Hennig, 'Observation of a fast response in functional MR,' Magn. Reson. Med., vol. 32, no. 1, pp.146-149, 1994   DOI
2 R.S. Menon, S. Ogawa, X. Hu, J.P. Strupp, P. Anderson, and K. Ugurbil, 'BOLD based functional MRI at 4 Tesla includes a capillary bed contribution: echo-planar imaging correlates with previous optical imaging using intrinsic signals,' Magn. Reson. Med., vol. 33, no. 3, pp.453-459, 1995   DOI
3 J.R. Tregellas, J.L. Tanabe, D.E. Miller, and R. Freedman, 'Monitoring eye movements during fMRI tasks with echo planar images,' Hum. Brain Mapp., vol. 17, no. 4, pp.237-243, 2002   DOI   ScienceOn
4 K. Tsubota, K.K. Kwong, T.Y. Lee, J. Nakamura, and H.M. Cheng, 'Functional MRI of brain activation by eye blinking,' Exp. Eye Res., vol. 69, no. 1, pp.1-7, 1999   DOI   ScienceOn
5 F. Kruggel, C.J. Wiggins, C.S. Herrmann, and D.Y. von Cramon, 'Recording of the event-related potentials during functional MRI at 3.0 Tesla field strength,' Magn. Reson. Med., vol. 44, no. 2, pp.277-282, 2000   DOI   ScienceOn
6 P.J. Allen, O. Josephs, and R. Turner, 'A method for removing imaging artifact from continuous EEG recorded during functional MRI,' Neuroimage, vol. 12, no. 2, pp.230-239, 2000   DOI   ScienceOn
7 H. Kimming, M.W. Greenlee, F. Huethe, and T. Mergner, 'MR-Eyetracker: a new method for eye movement recording in functional magnetic resonance imaging,' Exp. Brain Res., vol. 126, no. 3, pp.443-449, 1999   DOI
8 M.S. Beauchamp, 'Detection of eye movements from fMRI data,' Magn. Reson. Med., vol. 49, no. 2, pp.376-380, 2003   DOI   ScienceOn
9 S. Ogawa, T.M. Lee, A.R. Kay, and D.W. Tank et al., 'Brain magnetic resonance imaging with contrast dependent on blood oxygenation,' in Proc. Natl. Acad. Sci., 1990, vol. 87, no. 24, pp.9868-9872
10 J. Talairach and P. Tournoux, Co-Planar Stereotaxic Atlas of the Human Brain, New York, Thieme Medical Publishers, 1988
11 P.A. Bandettini, E.C. Wong, R.S. Hinks, R.S. Tikofsky, and J.S. Hyde, 'Time course EPI of human brain function during task activation,' Magn. Reson. Med., vol. 25, no. 2, pp.390-397, 1992   DOI
12 L. Muckli, N. Kriegeskorte, H. Lanfermann, F.E. Zanella, W. Singer, and R. Goebel, 'Apparent motion: event-related functional magnetic resonance imaging of perceptual switches and States,' J. Neurosci., vol. 22, RC219, pp.1-5, 2002   PUBMED
13 P.J. Allen, G. Polizzi, K. Krakow, D.R. Fish, and L. Lemieux, 'Identification of EEG events in the MR scanner: the problem of pulse artifact and a method for its subtraction,' Neuroimage, vol. 8, no.3, pp.229-239, 1998   DOI   ScienceOn
14 P. Freitag, M.W. Greenlee, T. Lacina, K. Scheffler, and E.W. Radu, 'Effect of eye movements on the magnitude of functional magnetic resonance imaging responses in extrastriate cortex during visual motion perception,' Exp. Brain Res., vol. 119, no. 4, pp.409-414, 1998   DOI
15 G.M. Boynton, S.A. Engel, G.H. Glover, and D.J. Heeger, 'Linear systems analysis of functional magnetic resonance imaging in human V1,' J. Neurosci., vol. 16, no. 13, pp.4207-4221, 1996   DOI