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http://dx.doi.org/10.9718/JBER.2007.28.1.139

Activations of Cerebral and Cerebellar Cortex Induced by Repetitive Bilateral Motor Excercise  

Tae, Ki-Sik (Dept. of Biomedical Engineering, Konyang University)
Song, Sung-Jae (Dept. of Mechanical Engineering, Wonju National College)
Kim, Young-Ho (Department of Biomedical Engineering, Yonsei University)
Publication Information
Journal of Biomedical Engineering Research / v.28, no.1, 2007 , pp. 139-147 More about this Journal
Abstract
The aim of this study was to evaluate effects of short-tenn repetitive-bilateral excercise on the activation of motor network using functional magnetic resonance imaging (fMRI). The training program was performed at 1 hr/day, 5 days/week during 6 weeks. Fugl-Meyer Assessments (FMA) were performed every two weeks during the training. We compared cerebral and cerebellar cortical activations in two different tasks before and after the training program: (1) the only unaffected hand movement (Task 1); and (2) passive movements of affected hand by the active movement of unaffected hand (Task 2). fMRI was performed at 3T with wrist flexion-extension movement at 1 Hz during the motor tasks. All patients showed significant improvements of FMA scores in their paretic limbs after training. fMRI studies in Task 1 showed that cortical activations decreased in ipsilateral sensorimotor cortex but increased in contralateral sensorimotor cortex and ipsilateral cerebellum. Task 2 showed cortical reorganizations in bilateral sensorimotor cortex, premotor area, supplemetary motor area and cerebellum. Therefore, this study demonstrated that plastic changes of motor network occurred as a neural basis of the improvement subsequent to repetitive-bilateral excercise using the symmetrical upper-limb ann motion trainer.
Keywords
cerebellum; cerebrum; cortical activation; FMA; fMRI; repetitive-bilateral exercise; reorganization;
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