Browse > Article
http://dx.doi.org/10.9718/JBER.2006.27.2.064

Patch-based Cortical Source Modeling for EEG/MEG Distributed Source Imaging: A Simulation Study  

Im Chang-Hwan (Department of Biomedical Engineering, Yonsei University)
Publication Information
Journal of Biomedical Engineering Research / v.27, no.2, 2006 , pp. 64-72 More about this Journal
Abstract
The present study introduces a new cortical patch-based source model for EEG/MEG cortical source imaging to consider anatomical constraints more precisely. Conventional source models for EEG/MEG cortical source imaging have used coarse cortical surface mesh or sampled small number of vertices from fine surface mesh, and thus they failed to utilize full anatomical information which nowadays we can get with sub-millimeter modeling accuracy. Conventional ones placed a single dipolar source on each cortical patch and estimated its intensity by means of various inverse algorithms; whereas the suggested cortical patch-based model integrates whole cortical area to construct lead field matrix and estimates current density that is assumed to be constant in each cortical patch. We applied the proposed and conventional models to realistic EEG data and compared the results quantitatively. The quantitative comparisons showed that the proposed model can provide more precise spatial descriptions of neuronal source distribution.
Keywords
EEG; MEG; brain mapping; inverse problem; lead field construction; cortical source imaging;
Citations & Related Records
연도 인용수 순위
  • Reference
1 A.M. Dale, A.K. Liu, B.R. Fischl, R.L. Buckner, J.W. Belliveau, J.D. Lewine, and E. Halgren, 'Dynamic Statistical Parametric Mapping: Combining fMRI and MEG for High-Resolution Imaging of Cortical Activity', Neuron, Vol. 26, pp.55-67, 2000   DOI   ScienceOn
2 B. He, Modeling and Imaging of Bioelectric Activity: Principles and Applications, Kluwer Academic/Plenum Publishers, 2004
3 B. He, Neural Engineering, Kluwer Academic/Plenum Publishers, 2005
4 W.E. Kincses, C. Braun, S. Kaiser, and T. Elbert, 'Modeling extended sources of event-related potentials using anatomical and physiological constraints', Hum. Brain Mapp., Vol. 8, pp. 182-193,1999   DOI   ScienceOn
5 A.K. Liu, J.W. Belliveau, and A.M. Dale, 'Spatiotemporal imaging of human brain activity using functional MRI constrained magnetoencephalography data: Monte Carlo simulations', Proc. Natl. Acad. Sci. USA, Vol. 95, pp.8945-8950, 1998
6 I.F. Gorodnistky, J.S. George, and B.D. Rao, 'Neuromagnetic imaging with FOCUSS: a recursive weighted minimum norm algorithm', Electroencephal. Clin. Neurophysiol., Vol. 95, pp.231-251, 1995   DOI   ScienceOn
7 K. Sekihara, S.S. Nagarajan, D. Poeppel, A Marantz, Y. Miyashita, 'Reconstructing spatia-temporal activities of neural sources using an MEG vector beamformer technique', IEEE Trans. Biomed. Eng., Vol. 48, pp.760-771, 2001   DOI   ScienceOn
8 A.M. Dale, B. Fischl, and M.I. Sereno, 'Cortical Surface-Based Analysis I. Segmentation and Surface Reconstruction', Neuroimage, Vol. 9, pp.179-194, 1999   DOI   ScienceOn
9 J. Haueisen, C. Ramon, M. Eiselt, H. Brauer, and H. Nowak, 'Influence of tissue resistivities on neuromagnetic fields and electric potentials studied with a finite element model of the head', IEEE Trans. Biomed. Eng., Vol. 44, pp.727-735, 1997   DOI   ScienceOn
10 F. Babiloni, C. Babiloni, F. Carducci, G.L. Romani, P.M Rossini, L.M. Angelone, and F. Cincotti, 'Multimodal integration of high-resolution EEG and functional magnetic resonance imaging data: a simulation study', Neuroimage, Vol. 19, pp.1-15, 2003   DOI   ScienceOn
11 F. Babiloni, F. Cinocotti, C. Babiloni, F. Carducci, D. Mattia, L. Astolfi, A Basilisco, P.M. Rossini, L. Ding, Y. Ni, J. Cheng, K. Christine, J. Sweeney, and B. He, 'Estimation of the cortical functional connectivity with the multimodal integration of highresolution EEG and fMRI data by directed transfer function', Neuroimage, Vol. 24, pp.118-131, 2005   DOI   ScienceOn
12 S. Baillet, Toward Functional Brain Imaging of Cortical Electrophysiology Markovian Models for Magneto and Electroencephalogram Source Estimation and Experimental Assessments, University of Paris XI: Ph. D. dissertation, 1998
13 B. Fischl, M.L Sereno, and AM. Dale, 'Cortical Surface-Based Analysis II. Inflation, Flattening, and a Surface-Based Coordinate System', Neuroimage, Vol. 9, pp.195-207, 1999   DOI   ScienceOn
14 B. He, X. Zhang, J. Lian, H. Sasaki, D. Wu, and V.L. Towle, 'Boundary element method-based cortical potential imaging of somatosensory evoked potentials using subjects' magnetic resonance images', Neuroimage, Vol. 16, pp.564-576, 2002   DOI   ScienceOn
15 E. Suarez, M.D. Viegas, M. Adjouadi, and A Barreto, 'Relating induced changes in EEG signals to orientation of visual stimuli using the ESI-256 machine', Biomed. Sci. Instrum., Vol. 36, pp. 33-38, 2000
16 R.P. Dhond, K. Marinkovic, A.M. Dale, T. Witzel, and E. Halgren, 'Spatiotemporal maps of past-tense verb inflection', Neuroimage, Vol. 19, pp.91-100, 2003   DOI   ScienceOn
17 AM. Dale and M.I Sereno, 'Improved localization of cortical activity by combining EEG and MEG with MRI surface reconstruction: a linear approach', J. Cogn. Neurosci., Vol. 5, pp.162176, 1993   DOI   ScienceOn
18 S. Baillet, J.C. Mosher, and R.M Leahy, 'Electromagnetic Brain Mapping', IEEE Signal Process. Mag., No. 11, pp.14-30, 2001
19 O. David and L. Gamero, 'Time-Coherent Expansion of MEG/ EEG Cortical Sources', Neuroimage, Vol. 17, pp.1277-1289, 2002   DOI   ScienceOn
20 C.H. Im, K.O. An, H.K Jung, H. Kwon, Y.H. Lee, 'Assessment criteria for MEG/EEG cortical patch tests', Phys. Med. BioI., Vol. 48, pp.2561-2573, 2003   DOI   ScienceOn
21 P. L. Nunez and R B. Silberstein, 'On the relationship of synaptic activity to macroscopic measurements: Does co-registration of EEG with fMRI make sense?', Brain Topogra., Vol. 13, pp.79-96, 2000   DOI   ScienceOn
22 D.W. Shattuck and R.M. Leahy, 'BrainSuite: An automated cortical surface identification tool', Med. Image Anal., Vol. 6, pp.129-142, 2002   DOI   ScienceOn
23 M.S. Hamalainen and J. Sarvas, 'Realistic conductivity geometry model of the human head for interpretation of neuromagnetic data', IEEE Trans. Biomed. Eng., Vol. 36, pp.165-171, 1989   DOI   ScienceOn
24 B. He, T. Musha, Y. Okamoto, S. Homma, Y. Nakajima, and T. Sato, 'Electric dipole tracing in the brain by means of the boundary element method and its accuracy', IEEE Trans. Biomed. Eng., Vol. 34, pp.406-414, 1987   DOI   ScienceOn
25 F. Darvas, D. Pantazis, E. Kucukaltun-Yildirim, and R.M. Leahy, 'Mapping human brain function with MEG and EEG: methods and validation', Neuroimage, Vol. 23, pp.S289-S299, 2004   DOI   ScienceOn
26 A.K Liu, A.M. Dale, and J.W. Belliveau, 'Monte Carlo simulation studies of EEG and MEG localization accuracy', Hum. Brain Mapp., Vol. 16, pp.47-62, 2002   DOI   ScienceOn
27 F.H. Lin, T. Witzel, M.S. Hamalainen, A.M Dale, J.W. Belliveau, and S.M. Stufflebeam, 'Spectral spatiotemporal imaging of cortical oscillations and interations in the human brain', Neuroimage, Vol. 23, pp.582-595, 2004   DOI   ScienceOn
28 H. Buchner, G. Knoll, M Fuchs, A Rienacker, R Beckmann, M. Wagner, J. Silny, and P. Jorg, 'Inverse localization of electric dipole current sources in finite element models of the human head', Electroenceph. Clin. Neurophysiol., Vol. 102, pp.267-278, 1997   DOI   ScienceOn
29 M. Fuchs, M. Wagner, T. Kohler, and H.A Wischmann, 'Linear and nonlinear current density reconstructions', J. Clin. Neurophysiol., Vol. 16, pp.267-295, 1997
30 S. Baillet, J.J. Riera, G. Marin, J.F. Mangin, J. Aubert, and L. Gamero, 'Evaluation of inverse methods and head models for EEG source localization using a human skull phantom', Phys. Med. BioI., Vol. 46, pp.77-96, 2001   DOI   ScienceOn
31 M. Chupin, S. Baillet, C. Okada, D. Hasboun, and L. Garnero, 'On the detection of hippocampus activity with MEG.', Proc. Int. Conf. Biomagnetism (BIOMAG2002), 2002
32 C. Babiloni, 'Linear inverse source estimate of combined EEG and MEG data related to voluntary movements', Hum. Brain Mapp., Vol. 14, pp.197-209, 2001   DOI   ScienceOn
33 B. Fischl and A.M. Dale, 'Measuring the thickness of the human cerebral cortex from magnetic resonance images', Proc. Natl. Acad. Sci. USA, Vol. 97, pp.11050-11055, 2000   DOI   ScienceOn
34 F.H. Lin, J.W. Belliveau, A.M. Dale, and M.S. Hamalainen, 'Distributed current estimates using cortical orientation constraints', Hum. Brain Mapp., Vol. 27, pp.1-13, 2006   DOI   ScienceOn