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Zoom-in X-ray Micro Tomography System  

Chun, In-Kon (Department of Biomedical Engineering, Kyung Hee University)
Lee, Sang-Chul (Department of Biomedical Engineering, Kyung Hee University)
Park, Jeong-Jin (Department of Biomedical Engineering, Kyung Hee University)
Cho, Min-Hyoung (Department of Biomedical Engineering, Kyung Hee University)
Lee, Soo-Yeol (Department of Biomedical Engineering, Kyung Hee University)
Publication Information
Journal of Biomedical Engineering Research / v.26, no.5, 2005 , pp. 295-300 More about this Journal
Abstract
We introduce an x-ray micro tomography system capable of high resolution imaging of a local region inside a small animal. By combining two kinds of projection data, one from a full field-of-view (FOV) scan of the whole body and the other from a limited FOV scan of the region of interest, we have obtained zoomed-in images of the region of interest without any contrast a nomalies. We have integrated a micro tomography system using a micro-focus x-ray source, a $1248\times1248$ flat-panel x-ray detector, and a precision scan mechanism. Using the cross-sectional images taken with the zoom-in micro tomography system, we measured trabecular thicknesses of femur bones in postmortem rats. To compensate the limited spatial resolution in the zoom-in micro tomography images, we used the fuzzy distance transform for the calculation of the trabecular thickness. To validate the trabecular thickness measurement with the zoom-in micro tomography images, we compared the measurement results with the ones obtained from the conventional micro tomography images of the extracted bone samples.
Keywords
Zoom-in micro tomography; Flat panel detector; Fuzzy distance transform; Trabecular thickness; Osteoporosis;
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