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Modeling and Simulation of the Cardiovascular System Using Baroreflex Control Model of the Heart Activity  

Choi Byeong Cheol (Dept. of Biomedical Engineering, Choonhae College)
Jeong Do Un (Dept. of Interdisciplinary Program in Biomedical Engineering, Pusan National University)
Shon Jung Man (Dept. of Interdisciplinary Program in Biomedical Engineering, Pusan National University)
Yae Su Yung (Dept. of Interdisciplinary Program in Biomedical Engineering, Pusan National University)
Kim Ho Jong (Dept. of Computer Aided Design, Doowoon Technical College)
Lee Hyun Cheol (Dept. of Computer Aided Design, Doowoon Technical College)
Kim Yun Jin (Dept. of Family Medicine, College of Medicine, Pusan National University)
Jung Dong keun (Dept. of Biomedical Engineering, College of Medicine, Dong-A University)
Yi Sang Hun (Dept. of computer Aided Science, Inje University)
Jeon Gye Rok (Dept of Biomedical Engineering, College of Medicine, Pusan National University)
Publication Information
Journal of Biomedical Engineering Research / v.25, no.6, 2004 , pp. 565-573 More about this Journal
Abstract
In this paper, we proposed a heart activity control model for simulation of the aortic sinus baroreceptor, which was the most representative baroreceptor sensing the variance of pressure in the cardiovascular system. And then, the heart activity control model composed electric circuit model of the cardiovascular system with baroreflex control and time delay sub-model to observe the effect of time delay in heart period and stroke volume under the regulation of baroreflex in the aortic sinus. The mechanism of time delay in the heart activity baroreflex control model is as follows. A control function is conduct sensing pressure information in the aortic sinus baroreceptor to transmit the efferent nerve through central nervous system. As simulation results of the proposed model, we observed three patterns of the cardiovascular system variability by the time delay. First of all, if the time delay over 2.5 second, aortic pressure and stroke volume and heart rate was observed non-periodically and irregularly. However, if the time delay from 0.1 second to 0.25 second, the regular oscillation was observed. And then, if time delay under 0.1 second, then heart rate and aortic pressure-heart rate trajectory were maintained in stable state.
Keywords
Modeling and simulation; Cardiovascular system; Baroreflex control model;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
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