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Development of a Micro-CT System for Small Animal Imaging  

Sang Chul Lee (Graduate School of East-West Medical Science, Kyung Hee University)
Ho Kyung Kim (School of Mechanical Engineering, Pusan National University)
In Kon Chun (Graduate School of East-West Medical Science, Kyung Hee University)
Myung Hye Cho (Graduate School of East-West Medical Science, Kyung Hee University)
Min Hyoung Cho (Graduate School of East-West Medical Science, Kyung Hee University)
Soo Yeol Lee (Graduate School of East-West Medical Science, Kyung Hee University)
Publication Information
Journal of Biomedical Engineering Research / v.25, no.2, 2004 , pp. 97-102 More about this Journal
Abstract
We developed an x-ray cone-beam micro computed tomography (micro-CT) system for small-animal imaging. The micro-CT system consists of a 2-D flat-panel x-ray detector with a field-of-view (FOV) of 120${\times}$120 mm2, a micro-focus x-ray source, a scan controller and a parallel image reconstruction system. Imaging performances of the micro-CT system have been evaluated in terms of contrast and spatial resolution. The minimum resolvable contrast has been found to be less than 36 CT numbers at the dose of 95 mGy and the spatial resolution about 14 lp/mm. As small animal imaging results, we present high resolution 3-D images of rat organs including a femur, a heart and vessels. We expected that the developed micro-CT system can be greatly used in biomedical studies using small animals.
Keywords
Micro tomography; Small animal imaging; Flat panel detector; Performance evaluation; 3D reconstruction;
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