Browse > Article

Reconstruction of Myocardial Current Distribution Using Magnetocardiogram and its Clinical Use  

권혁찬 (한국표준과학연구원 생체자기계측센터)
정용석 (한국표준과학연구원 생체자기계측센터)
이용호 (한국표준과학연구원 생체자기계측센터)
김진목 (한국표준과학연구원 생체자기계측센터)
김기웅 (한국표준과학연구원 생체자기계측센터)
김기영 (건양대학교 의과대학 심장내과)
박기락 (건양대학교 의과대학 심장내과)
배장호 (건양대학교 의과대학 심장내과)
Publication Information
Journal of Biomedical Engineering Research / v.24, no.5, 2003 , pp. 459-464 More about this Journal
Abstract
The source current distribution in a heart was reconstructed from the magnetocardiogram (MCG) and its clinical usefulness was demonstrated. MCG was measured using 40-channel superconducting quantum interference device (SQUID) gradiometers for a patient of Wolff-Parkinson-White (WPW) syndrome, which has an accessory pathway between the atria and the ventricles. Reconstruction of source current distribution in a plane below the chest surface was performed using minimum norm estimation (MNE) algorithm and truncated singular value decomposition (SVD), In the simulation, we confirmed that the current distributions. which were computed for the test dipoles, represented well the essential feature of the test current configurations, In the current map of WPW syndrome, we observed abnormal currents that would bypass the atrioventricular junction at a delta wave. However, we could not observe such currents any more after the surgery. These results showed that the obtained current distribution using MCG signals is consistent with the electrical activity in a heart and has clinical usefulness.
Keywords
SQUID; Magnetocardiogram; SQUID; minimum norm estimation; current reconstruction; WPW syndrome;
Citations & Related Records
연도 인용수 순위
  • Reference
1 G. Stroink, W. Moshage and S. Achenbach, 'Cardiomagnetism', in Magnetism in medicine, eds. W. Andra and H. Nowak, Berlin, Wiley-VCH, pp. 136-189, 1998
2 W. Moshage, S. Achenbach, K. Gohl and K. Bachmann, 'Evaluation of the non invasive localization accuracy of cardiac arrhythmias attainable by multichannel mngnetocardiography(MCG)', lnt J Card Imaging, Vol. 12, pp. 47-59, 1996
3 R. Killmann et aI, 'Localization of myocardial ischemia from the magnetocardiogram using current density reconstruction method: computer simulation study', Med BioI Eng Cornput, Vol. 33, pp. 643-651, 1995
4 H. Michael et aI, 'Identification of a Gene Responsible for Familial Wolff-Parkinson- White Syndrome', N engl J Med, Vol. 344, pp. 1824-1831, 2001
5 H. Kwon, Y.H Lee and J.M. Kim, 'Source Current Reconstruction Based on MCG Singal', Progress in Superconductivity, Vol. 4, pp. 48-52, 2002
6 H. Brauer et aI, 'Reconstruction of Extended Current Sources in a Human Body Phantom Applying Biomagnetic Measuring Techniques', IEEE Trans Magri vol. 36, pp. 1700-1705, 2000
7 최윤식, 임상심전도학, 서울대학교 출판부, 1997
8 M. Makijarvi et aI, 'Magnetocardiography: supra ventricular arrhythmias and pre excitation syndromes', Eur Heart J, Vol. 14, pp. 46-52, 1993
9 K. Tsukada et ai, 'Multichannel SQUID system detecting tangential components of cardiac magnetic field', Rev Sci Instrum vol. 66, pp. 5085-5091, 1995
10 Y.H. Lee et aI, 'Construction of a 40 channel SQUID System and Its application to Neuromngnetic Measurements', Progress in Superconductivity, Vol. 2, pp. 20-26, 2001
11 J. Nenonen, M. Hamalainen and R. Ilmoniemi, 'Minimum norm estimation in a boundary element torso model,' Med & BioI Eng & Comput, Vol. 32, pp. 43-48, 1994