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Analysis of Bone-Remodeling Process Using Quasi-molecular Dynamics  

김영은 (단국대학교 기계공학과)
최훈희 (단국대학교 대학원)
Publication Information
Journal of Biomedical Engineering Research / v.24, no.5, 2003 , pp. 447-451 More about this Journal
Abstract
A new method for analyzing the bone-remodeling process using quasi-molecular dynamics was proposed in this study. The effect of pressure due to bone marrow, which could not be considered in previous methods, was also considered in this method. Bone-remodeling response of the 2D vertebral body of lumbar spine to a uniaxial compressive displacement of 1.8564mm. corresponding to approximately 2kN of compressive load, was studied. Converged shape change of the cortical shell and rearrangement of cancellous bone structure matched well with a normal shape of the vertebral body. The calculated responses in the spinal elements also shows closed results compared with experimental results.
Keywords
Bone Remodeling; Quasi-molecular Dynamics; Lumbar Spine; Vertebral Body;
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  • Reference
1 K. Firoozbakhsh, and S.C. Cowin, 'Devolution of inhomogeneities in bone structure-predictions of adaptive elasticity theory', J. of Biomechanics, Vol. 102, pp.287-293, 1980
2 D.D. Cody, E.B. Brown, and M.J. Flynn, 'Regional bone density distribution in female spinest(T6-L4)', 38th Annual Meeting, Orthopedic Research Society, Feb. 17-20, p.449, 1992
3 D. Greenspan, Quasimolecular modeling, World Scientific, Singapore, 1991
4 M.G. Mullender, R. Huiskes, and H Weinans, 'A physiological approach to the simulation of bone remodeling as a self-organization control process', J. of Biomechanics, Vol. 27, pp.1389-1394, 1994
5 M.P. Allen and D.J. Tildesley, Computer simulation of liquids, Oxford University Press, 1989
6 D.C. Rapaport, The art of molecular dynamics simulation, Cambridge University Press, 1995
7 T.S. Keller, T.H. Hannson, A.C. Abram, D.M. Spengler, and M.M Panjabi, 'Regional variation in ther compressive properties of lumbar vertebral trabeculae: Effect of disc degeneration', Spine, Vol. 14, pp.1012-1019, 1989
8 V.J. Goel, S.A. Ramirez, W. Gong, and L.G. Gilberton, 'Cancellous bone Young's modulus variation within the vertebral body of a ligamentous lumbar spine-Application of bone adaptive remodeling concepts', J. of Biomechanical Engineering, Vol. 117, pp.266-271, 1995