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The Development of 63nm Diode Laser System for Photodynamic Therapy of Cancer  

임현수 (충남대학교 의과대학 의공학교실)
Publication Information
Journal of Biomedical Engineering Research / v.24, no.4, 2003 , pp. 319-328 More about this Journal
Abstract
The purpose of this paper is to develop a medical laser system using the semiconductor diode laser in order to photodynamic cancel therapy as a light source. The ideal light source for photodynamic therapy would be a homogeneous nondiverging light with variable spot size and specific wavelength with stability. After due consideration in this point, in this paper, we used a diode laser resonator of 635nm wavelength. The development laser system have a statistical laser out beam with accuracy control using the constant current control of method and clinic-friendly with compact. In order to protect the diode resonator from the over-current, the rush-current and electrical fault, we specially designed. The most importance therapeutic factor are the radiation mode for cancer therapy. So we developed the radiation mode of CW(Continuous Wave), long pulse, short pulse, and burst pulse and can adjust the exposure time from several milli-second to several minute. The experimental result shows that laser beam power was increased linear from 10mW to 300mW according to the increasing input current and the increasing exposure time. The developed new compact diode laser system have a stability of output power and specific wavelength with easy control and transportable for many applications of PDT.
Keywords
Photodynamic Therapy; Photofrin; Tumour cell; Laser;
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Times Cited By KSCI : 1  (Citation Analysis)
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