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A Study on Visuospatial Cognitive Performance Following Oxygen Administration using fMRI  

정순철 (건국대학교 의과대학 의학공학부)
김익현 (건국대학교 의과대학 의학공학부)
이봉수 (건국대학교 의과대학 의학공학부)
이정미 (충남대학교 심리학과 뇌과학 연구소)
손진훈 (충남대학교 심리학과 뇌과학 연구소)
김승철 ((주)옥시큐어)
Publication Information
Journal of Biomedical Engineering Research / v.24, no.4, 2003 , pp. 267-273 More about this Journal
Abstract
The present study attempted to observe what changes the supply of highly concentrated (30%) oxygen cause to people's ability of visuospatial cognition, compared to air of normal oxygen concentration (21%). This study sampled eight male university students (the average age : 23.5) as subjects for functional Magnetic Resonance Imaging (MRI) study It also developed equipment that supplies 21% and 30% oxygen) at a constant rate of 8L/min. Two questionnaires containing 20 questions were developed to measure the ability of visuospatial cognition, and accuracy was calculated from the result of task performance. The experiment paradigm consisted of the run conducting tasks at 30%'s concentration of oxygen and another run at 21%'s concentration of oxygen. Each run was composed of four blocks and each block included eight control tasks and five visuospatial taks. 3T MRI was used and fMRI was obtained through the single-shot EPI method. The activation in the occipital-associated area, bilateral superior parietal lobes, bilateral inferior parietal lobes. bilateral precuneus, bilateral postcentral gyri, bilateral middle frontal gyri, bilateral inferior frontal gyri, bilateral medial frontal gyri, bilateral superior frontal gyri, bilateral cingulate gyri was significantly increased at the 30%'s concentration of oxygen rather than 21%'s. Furthermore, the result of task performance showed the accuracy increased at 30%'s concentration of oxygen rather than 21%'s. From the result of this study, it is concluded that the supply of highly concentrated oxygen has a positive effect on the ability of visuospatial cognition.
Keywords
Visuospatial cognitive performance; Oxygen administration; fMRI; Accuracy;
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1 Healthy aging, memory subsystems and regional cerebral oxygen consumption /
[ F.Eustsche;P.Rioux;B.Desgranges;G.Marchal;M.C.Petittaboue;M.Dary;B.Lechevalier;J.C.Baron ] / Neuropsychologia   DOI   ScienceOn
2 Glycaemic control and neuropsycho-logic function during hypoglaecemia in patients with insulin dependent diabets mellitis /
[ B.Widom;D.C.Simonson ] / Ann. Intern. Med.   DOI   ScienceOn
3 An fMRI study of sex differences in regional activation to a verbal and a spatial task /
[ R.C.Gur;D.Alsop;D.Glahn;R.Petty;C.L.Swanson;J.A.Maldjian;B.I.Turetsky;J.A.Detre;J.Gee;R.E.Gur ] / Brain and Language   DOI   ScienceOn
4 /
[ S.R.Lee;K.R.Kim ] / Aptitude test 251-Ga (High school students~adults)
5 Effect of high terrestrial altitude and supplemental oxygen on human performance and mood /
[ J.S.Crowley;N.W.Wesenten;G.Kamimori;M.E.Devine;E.Iwanyk;T.Balkin ] / Aviat. Space Environ. Med.
6 Oxygen administration enhances memory formation in healthy young adults /
[ M.C.Moss;A.B.scholey ] / Psychopharmacology   DOI
7 Activation of human language processing brain regions after the presentation of random letter strings demonstrated with event-related functional magnetic resonance imaging /
[ F.Jessen;M.Erb;U.Klose;M.Lotze;W.Grodd;R.Heun ] / Neuroscience Letters   DOI   ScienceOn
8 /
[ S.R.Lee ] / Inteligence test 151-Ga Type(High school students~adults)
9 Brain dysfunction in mild to moderate hypoxia /
[ G.E.Gibson;W.Pulsinelli;J.P.Blass;T.E.Duffy ] / Am. J. Med.   DOI   ScienceOn
10 Event-related functional MRI: Implications for cognitive psychology /
[ M.D'Esposite;E.Zarahn;G.E.Aguirre ] / Psychological Bulletin   DOI   ScienceOn
11 Graded functional activation in the visuospatial system with the amount of task demand /
[ P.A.Carpenter;M.A.Just;T.A.Keller;W.Eddy;K.Thulborn ] / Journal of Cognitive Neuroscience   DOI   ScienceOn
12 The neural basis of vertical and horizontal line bisection judgements: an fMRI study of normal volunteers /
[ G.R.Fink;J.C.Marshall;P.H.Weiss;K.Zilles ] / Neuroimage   DOI   ScienceOn
13 Cognitive function during mederate hypoxaemia /
[ J.Noble;J.G.Jones;E.J.Davis ] / Anaesth. Intens. Care
14 /
[ J.Talairach;P.Tournoux ] / Co-Planar Stereotaxic Atlas of the Human Brain
15 The effects of blood sugar level changes on cognitive function, affective state and somatic symptoms /
[ L.A.Taylor;S.J.Rachman ] / J. Behav. Med   DOI
16 /
[ S.B.Park ] / GATB(General Aptitude Test Battery): academic, job aptitude test type Ⅱ(for students of middle schools, high schools and universities, and general public)
17 Network analysis of brain cognitive function using metabolic and blood-flow data /
[ B.Horwitz;A.R.McIntosh;J.V.Haxby;C.L.Grady ] / Behav. Brain Res.   DOI   ScienceOn
18 Heart rate and oxygen consumption during mental arithmetic, a video game, and graded exercise: Further evidence of metabolically-exaggerated cardiac adjustments /
[ J.R.Turner;D.Carrol ] / Psychophysiology   DOI   ScienceOn
19 Cortical activity of good and poor spatial test performances during and spatial and verbal processing studied with slow potential topography /
[ O.Vitouch;H.Bauer;G.Gittler;M.Leodolter;U.Leodolter ] / International Journal of Psychology
20 Positron emission tomographic studies of local cerebral glucose metabolism in humans in physiological and pathological conditions /
[ M.Reivich;A.Alavi ] / Add. Metabol. Dis.
21 Hypoglycaemic-induced cognitive dysfunction in diabetes mellitusl: Effect of hypoglycaemic unawareness /
[ P.E.Gold;K.M.Macleod;I.J.Deary;B.M.Frier ] / Physiol. Behav   DOI   ScienceOn
22 Metabolic mapping of the brain's response to visual stimulation: Studies in humans /
[ M.E.Phelps;D.E.Khul;J.C.Mazzioti ] / Science   DOI
23 Cognitive performance, hyperoxia, and heart rate following oxygen administration in healthy young adult /
[ A.B.Scholey;M.C.Moss;N.Neave;K.Wesnes ] / Physiology & Behavior   DOI   ScienceOn
24 Hemispheric preference in visuospatial processing: a complementary approach with fMRI and lesion studies /
[ V.W.Ng;P.J.Eslinger;S.C.Williams;M.J.Brammer;E.T.Bullmore;C.M.Andrew;J.Suckling;R.G.Morris;A.L.Benton ] / Human Brain Mapping   DOI   ScienceOn
25 Intrinsic signal changes accompanying sensory stimulation: Functional brain mapping with magnetic resonance imaging /
[ S.Ogawa;D.W.Tank;R.Menon;J.M.Ellermann;S.G.Kim;H.Merkle;K.Ugurbil ] / Proc. Natl. Acad. Sci.   DOI   ScienceOn
26 Effects of oxygen and refresh space for the elderly /
[ T.Fujiwara;M.Maeda ] / J. Human Life Engineering
27 Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation /
[ K.K.Kwong;J.W.Belliveau;D.A.Chesler;I.E.Goldberg;R.M.Weisskoff;B.P.Poncelet;D.N.Kennedy;B.E.Hoppel;M.S.Cohen;R.Turner;H.M.Cheng;T.J.Brady;B.R.Rosen ] / Proc. Natl. Acad. Sci.   DOI   ScienceOn
28 Brain areas activated by different levels of individual's visuospatial ability: an fMRI study /
[ J.H.Sohn;Y.H.Kim;K.H.Lee;S.H.Park ] / Korean Journal of Brain Science and Technology