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http://dx.doi.org/10.5230/jgc.2017.17.e18

Botulinum Toxin Injection for the Treatment of Delayed Gastric Emptying Following Pylorus-Preserving Gastrectomy: an Initial Experience  

Lee, Jung Hwan (Center for Gastric Cancer, National Cancer Center)
Kim, Chan Gyoo (Center for Gastric Cancer, National Cancer Center)
Kim, Young-Woo (Center for Gastric Cancer, National Cancer Center)
Choi, Il Ju (Center for Gastric Cancer, National Cancer Center)
Lee, Jong Yeul (Center for Gastric Cancer, National Cancer Center)
Cho, Soo-Jeong (Center for Gastric Cancer, National Cancer Center)
Kim, Young-Il (Center for Gastric Cancer, National Cancer Center)
Eom, Bang Wool (Center for Gastric Cancer, National Cancer Center)
Yoon, Hong Man (Center for Gastric Cancer, National Cancer Center)
Ryu, Keun Won (Center for Gastric Cancer, National Cancer Center)
Publication Information
Journal of Gastric Cancer / v.17, no.2, 2017 , pp. 173-179 More about this Journal
Abstract
Purpose: To report our experience of endoscopic botulinum toxin injection in patients who experienced severe delayed gastric emptying after pylorus-preserving gastrectomy (PPG). Materials and Methods: We reviewed the medical records of 6 patients who received the botulinum toxin injection. They presented with severe delayed gastric emptying in the early postoperative period. Endoscopic botulinum toxin was administered as 4 injections of 25-50 IU into each of the 4 quadrants of the prepyloric area. Results: All botulinum toxin injections were successful without any complications, enabling 5 patients to tolerate soft solid diets and one to tolerate a soft fluid diet within 10 days. The endoscopic criteria of 4 patients improved. Symptom recurrence caused 2 patients to undergo repeat injections that were successful. The median follow-up period was 27 months, and all patients could ingest normal regular diets at the last follow-up. Conclusions: Endoscopic botulinum toxin injection is a feasible treatment option for early delayed gastric emptying after PPG.
Keywords
Surgery; Gastric stasis; Gastrectomy; Complications; Endoscopy; Botulinum toxins;
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Times Cited By KSCI : 1  (Citation Analysis)
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