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http://dx.doi.org/10.5230/jgc.2012.12.4.217

Clinical Correlation between Gastric Cancer Type and Serum Selenium and Zinc Levels  

Ji, Jae Hyo (Department of Surgery, Seoul Medical Center)
Shin, Dong Gue (Department of Surgery, Seoul Medical Center)
Kwon, Yujin (Department of Surgery, Seoul Medical Center)
Cho, Dong Hui (Department of Surgery, Seoul Medical Center)
Lee, Kyung Bok (Department of Surgery, Seoul Medical Center)
Park, Sang Soo (Department of Surgery, Seoul Medical Center)
Yoon, Jin (Department of Surgery, Seoul Medical Center)
Publication Information
Journal of Gastric Cancer / v.12, no.4, 2012 , pp. 217-222 More about this Journal
Abstract
Purpose: We conducted this study to study the clinical correlation between the characteristics of gastric cancer and serum selenium and zinc levels. Materials and Methods: The following data were measured in the baseline serum selenium and zinc levels of 74 patients with curative gastrectomy subsequent to confirmed gastric cancer, from March 2005 to August 2012. Results: Among the 74 gastric cancer patients, 53 patients were male. Mean serum selenium and zinc levels were $118.7{\pm}33.1$ ug/L and $72.2{\pm}24.3$ ug/dl, respectively. Seven patients (9.5%) showed lower selenium level, and 33 patients (44.6%) showed lower zinc level. Serum Selenium level was $99.1{\pm}31.8$ ug/L in cardia cancer group (10 cases) and $121.8{\pm}32.4$ ug/L in non-cardia cancer group (64 cases)(P=0.044). According to tumor gross type, zinc level was $78.7{\pm}29.6$ ug/dl in early gastric cancer (33) and $66.9{\pm}17.8$ ug/dl in advanced gastric cancer (41) (P=0.064). Conclusions: The serum selenium level was highly correlated with the location of gastric cancer. The serum zinc level was lower in advanced gastric cancer.
Keywords
Stomach neoplasms; Selenium; Zinc;
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