Browse > Article
http://dx.doi.org/10.5230/jgc.2011.11.1.64

Intrahepatic Splenosis Mimicking Liver Metastasis in a Patient with Gastric Cancer  

Kang, Kyu-Chul (Department of Surgery, Soonchunhyang University College of Medicine)
Cho, Gyu-Seok (Department of Surgery, Soonchunhyang University College of Medicine)
Chung, Gui-Ae (Department of Surgery, Soonchunhyang University College of Medicine)
Kang, Gil-Ho (Department of Surgery, Soonchunhyang University College of Medicine)
Kim, Yong-Jin (Department of Surgery, Soonchunhyang University College of Medicine)
Lee, Moon-Soo (Department of Surgery, Soonchunhyang University College of Medicine)
Kim, Hee-Kyung (Department of Pathology, Soonchunhyang University College of Medicine)
Park, Seong-Jin (Department of Radiology, Soonchunhyang University College of Medicine)
Publication Information
Journal of Gastric Cancer / v.11, no.1, 2011 , pp. 64-68 More about this Journal
Abstract
A 54 year old man was referred to our hospital with gastric cancer. The patient had a history of splenectomy and a left nephrectomy as a result of a traffic accident 15 years earlier. The endoscopic findings were advanced gastric cancer at the lower body of the stomach. Abdominal ultrasonography (USG) and magnetic resonance imaging demonstrated a metastatic nodule in the S2 segment of the liver. Eventually, the clinical stage was determined to be cT2cN1cM1 and a radical distal gastrectomy, lateral segmentectomy of the liver were performed. The histopathology findings confirmed the diagnosis of intrahepatic splenosis, omental splenosis. Hepatic splenosis is not rare in patients with a history of splenic trauma or splenectomy. Nevertheless, this is the first report describing a patient with gastric cancer and intrahepatic splenosis that was misinterpreted as a liver metastatic nodule. Intra-operative USG guided fine needle aspiration should be considered to avoid unnecessary liver resections in patients with a suspicious hepatic metastasis.
Keywords
Stomach neoplasms; Splenosis; Neoplasm metastasis; Liver;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Shirabe K, Shimada M, Matsumata T, Higashi H, Yakeishi Y, Wakiyama S, et al. Analysis of the prognostic factors for liver metastasis of gastric cancer after hepatic resection: a multiinstitutional study of the indications for resection. Hepatogastroenterology 2003;50:1560-1563.
2 Lin WC, Lee RC, Chiang JH, Wei CJ, Chu LS, Liu RS, et al. MR features of abdominal splenosis. AJR Am J Roentgenol 2003;180:493-496.   DOI   ScienceOn
3 Hagman TF, Winer-Muram HT, Meyer CA, Jennings SG. Intrathoracic splenosis: superiority of technetium Tc 99m heatdamaged RBC imaging. Chest 2001;120:2097-2098.   DOI   ScienceOn
4 Shaw AFB, Shafi A. Traumatic autoplastic transplantation of splenic tissue in man with observations on the late results of splenectomy in six cases. J Pathol 1937;45:215-235.   DOI
5 Fleming CR, Dickson ER, Harrison EG Jr. Splenosis: autotransplantation of splenic tissue. Am J Med 1976;61:414-419.   DOI   ScienceOn
6 Marchant LK, Levine MS, Furth EE. Splenic implant in the jejunum: radiographic and pathologic findings. Abdom Imaging 1995;20:518-520.   DOI   ScienceOn
7 Bock DB, King BF, Hezmall HP, Oesterling JE. Splenosis presenting as a left renal mass indistinguishable from renal cell carcinoma. J Urol 1991;146:152-154.
8 De Vuysere S, Van Steenbergen W, Aerts R, Van Hauwaert H, Van Beckevoort D, Van Hoe L. Intrahepatic splenosis: imaging features. Abdom Imaging 2000;25:187-189.   DOI   ScienceOn
9 Stein S, Duarte PS, Alavi A, Zhuang H, Alavi JB. Multiple intraabdominal soft-tissue masses in a man awaiting liver transplantation: a case study and discussion. Am J Clin Oncol 2000;23:506-508.   DOI   ScienceOn
10 Lee JB, Ryu KW, Song TJ, Suh SO, Kim YC, Koo BH, et al. Hepatic splenosis diagnosed as hepatocellular carcinoma: report of a case. Surg Today 2002;32:180-182.   DOI   ScienceOn
11 D'Angelica M, Fong Y, Blumgart LH. Isolated hepatic splenosis: first reported case. HPB Surg 1998;11:39-42.   DOI   ScienceOn
12 Kondo M, Okazaki H, Takai K, Nishikawa J, Ohta H, Uekusa T, et al. Intrahepatic splenosis in a patient with chronic hepatitis C. J Gastroenterol 2004;39:1013-1015.   DOI   ScienceOn
13 Abu Hilal M, Harb A, Zeidan B, Steadman B, Primrose JN, Pearce NW. Hepatic splenosis mimicking HCC in a patient with hepatitis C liver cirrhosis and mildly raised alpha feto protein; the important role of explorative laparoscopy. World J Surg Oncol 2009;7:1.   DOI
14 Foroudi F, Ahern V, Peduto A. Splenosis mimicking metastases from breast carcinoma. Clin Oncol (R Coll Radiol) 1999;11:190-192.   DOI   ScienceOn
15 Nakajima T, Fujiwara A, Yamaguchi M, Makiyama A, Wakae T, Fujita K, et al. Intrahepatic splenosis with severe iron deposition presenting with atypical magnetic resonance images. Intern Med 2008;47:743-746.   DOI   ScienceOn