Browse > Article

Quality of Life of Long-term Survivors after a Subtotal or a Total Gastrectomy for Gastric Cancer  

Lee, Seung-Soo (Department of Surgery, Kyungpook National University Hospital)
Han, Sung-Won (Department of Surgery, Kyungpook National University Hospital)
Jeong, Hye-Yeon (Department of Surgery, Kyungpook National University Hospital)
Song, Jye-Won (Department of Surgery, Kyungpook National University Hospital)
Chung, Ho-Young (Department of Surgery, Kyungpook National University Hospital)
Yu, Wan-Sik (Department of Surgery, Kyungpook National University Hospital)
Publication Information
Journal of Gastric Cancer / v.10, no.1, 2010 , pp. 34-39 More about this Journal
Abstract
Purpose: The aim of this study was to compare quality of life of long-term survivors after a subtotal or a total gastrectomy for gastric cancer. Materials and Methods: The European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30 questionnaire and QLQ-STO22 questionnaire were used to assess quality of life of 166 patients on their 5th annual follow-ups after gastrectomy for gastric cancer. One hundred twenty-six patients underwent a subtotal gastrectomy and 40 patients a total gastrectomy. Results: The subtotal gastrectomy group revealed a trend to have better quality of life in functional scales (physical, role, emotional, cognitive and social), fatigue, pain, dyspnea, diarrhea and financial difficulties. The total gastrectomy group showed a trend to have better quality of life in the global health status and quality of life, nausea and vomiting, insomnia, appetite loss and constipation. In all scales of the EORTC QLQ-STO22, the subtotal gastrectomy group had a trend to have better quality of life. However these did not reach the statistical significance. Conclusion: Surgeons may not limit the extent of resection concerning long-lasting poor quality of life. Oncologically sound resection is recommended.
Keywords
Stomach neoplasms; Gastrectomy; Quality of life;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Vickery CW, Blazeby JM, Conroy T, Arraras J, Sezer O, Koller M, Rosemeyer D, Johnson CD, Alderson D; EORTC Quality of Life Group. Development of an EORTC diseasespecific quality of life module for use in patients with gastric cancer. Eur J Cancer 2001;37:966-971.   DOI   ScienceOn
2 Davies J, Johnston D, Sue-Ling H, Young S, May J, Griffith J, Miller G, Martin I. Total or subtotal gastrectomy for gastric carcinoma? A study of quality of life. World J Surg 1998; 22:1048-1055.   DOI   ScienceOn
3 Tyrväinen T, Sand J, Sintonen H, Nordback I. Quality of life in the long-term survivors after total gastrectomy for gastric carcinoma. J Surg Oncol 2008;97:121-124.   DOI   ScienceOn
4 Troidl H, Kusche J, Vestweber KH, Eypasch E, Maul U. Pouch versus esophagojejunostomy after total gastrectomy: a randomized clinical trial. World J Surg 1987;11:699-712.   DOI   ScienceOn
5 Anderson ID, Macintyre IM. Symptomatic outcome following resection of gastric cancer. Surg Oncol 1995;4:35-40.   DOI   ScienceOn
6 Cho BC, Jeung HC, Choi HJ, Rha SY, Hyung WJ, Cheong JH, Noh SH, Chung HC. Prognostic impact of resection margin involvement after extended (D2/D3) gasterctomy for advanced gastric cancer: a 15-year experience at a single institute. J Surg Oncol 2007;95:461-468.   DOI   ScienceOn
7 Svedlund J, Sullivan M, Liedman B, Lundell L, Sjöndin I. Quality of life after gastrectomy for gastric carcinoma: controlled study of reconstructive precedures. World J Surg 1997;21:422-433.   DOI   ScienceOn
8 Huang CC, Lien HH, Wang PC, Yang JC, Cheng CY, Huang CS. Quality of life in disease-free gastric adenocarcinoma survivors: impacts of clinical stages and reconstructive surgical procedures. Dig Surg 2007;24:59-65.   DOI   ScienceOn
9 Diaz De Liaño A, Oteiza Martínez F, Ciga MA, Aizcorbe M, Cobo F, Trujillo R. Impact of surgical procedure for gastric cancer on quality of life. Br J Surg 2003;90:91-94.   DOI   ScienceOn
10 Wu CW, Hsieh MC, Lo SS, Lui WY, P'eng FK. Quality of life of patients with gastric adenocarcinoma after curative gastrectomy. World J Surg 1997;21:777-782.   DOI   ScienceOn
11 Yu W, Lee CH, Chung HY. Quality of life after curative surgery in patients with gastric cancer: comparison between a subtotal gastrectomy and a total gastrectomy. J Korean Gastric Cancer Assoc 2001;1:44-49.
12 Bottomley A. The cancer patient and quality of life. Oncologist 2002;7:120-125.   DOI   ScienceOn
13 Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, Filiberti A, Flechtner H, Fleishman SB, de Haes JC, et al. The European organization for research and treatment of cancer QLQ-30: a quality of life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 1993;85:365-376.   DOI   ScienceOn
14 Bae JM, Kim S, Kim YW, Ryu KW, Lee JH, Noh JH, Sohn TS, Hong SK, Park SM, You CH, et al. Health-related quatliy of life among disease-free stomach cancer survivor in Korea. Qual Life Res 2006;15:1587-1596.   DOI   ScienceOn
15 Blazeby JM, Conroy T, Bottomley A, Vickery C, Arraras J, Sezer O, Moore J, Koller M, Turhal NS, Stuart R, et al. Clinical and psychometric validation of a questionnaire module, the EORTC QLQ-STO22, to assess quality of life in patients with gastric cancer. Eur J Cancer 2004;40:2260-2268.   DOI   ScienceOn
16 Yun YH, Park YS, Lee ES, Bang SM, Heo DS, Park SY, You CH, West K. Validation of the Korean version of the EORTC QLQ-C30. Qual Life Res 2004;13:863-868.
17 Kim DW, Kim YJ, Kim JM, Cho KS, Kim HS, Lee MS, Kim JJ, Lee HM, Mun C. Long term impact of laparoscopic assisted distal gastrectomy on quality of life. J Korean Gastric Cancer Assoc 2007;7:213-218.   과학기술학회마을   DOI
18 Roukos DH. Current advances and changes in treatment strategy may improve survival and quality of life in patients with potentially curable gastric cancer. Ann Surg Oncol 1999;6:46-56.   DOI   ScienceOn
19 Songun I, Bonenkamp JJ, Hermans J, van Krieken JH, van de Velde CJ. Prognostic value of resection-line involvement in patients undergoing curative resections for gastric cancer. Eur J Cancer 1996;32A:433-437.
20 Cascinu S, Giordani P, Catalano V, Aqostinelli R, Catalano G. Resection-line involvement in gastric cancer patients undergoing curative resection: implications for clinical management. Jpn J Clin Oncol 1999;29:291-293.
21 Cella DF, Tulsky DS, Gray G, Sarafian B, Linn E, Bonomi A, Silberman M, Yellen SB, Winicour P, Brannon J, et al. The functional assessment of cancer therapy scale: development and validation of the general measure. J Clin Oncol 1993;11: 570-579.
22 Greimel E, Thiel I, Peintinger F, Cegnar I, Pongratz E. Prospective assessment of quality of life of female cancer patients. Gynecol Oncol 2002;85:140-147.   DOI   ScienceOn
23 Spitzer WO, Dobson AJ, Hall J, Chesterman E, Levi J, Shepherd R, Battista RN, Catchlove BR. Measuring the quality of life in cancer patients: a concise QL-Index for use by physicians. J Chronic Dis 1981;34:585-597.   DOI   ScienceOn
24 Korenaga D, Orita H, Okuyama T, Moriguchi S, Maehara Y, Sugimachi K. Quality of life after gastrectomy in patients with carcinoma of the stomach. Br J Surg 1992;79:248-250.   DOI   ScienceOn
25 Kaptein AA, Morita S, Sakamoto J. Quality of life in gastric cancer. World J Gastroenterol 2005;11:3189-3196.
26 Calman KC. Quality of life in cancer patients--an hypothesis. J Med Ethics 1984;10:124-127.   DOI
27 Blazeby JM. The role of quality of life assessment in gastric cancer. Jpn J Clin Oncol 2000;30:246.   DOI
28 Erridge SC, Gaze MN, Price A, Kelly CG, Kerr GR, Cull A, MacDougall RH, Howard GC, Cowie VJ, Gregor A. Symptom control and quality of life in people with lung cancer: a randomized trial of two palliative radiotherapy fractionation schedules. Clin Oncol (R Coll Radiol) 2005;17:61-67.   DOI   ScienceOn
29 Kiebert GM, de Haes JC, van De Velde JC. The impact of breast-conserving treatment and mastectomy on the quality of life of early-stage breast cancer patients: a review. J Clin Oncol 1991;9:1059-1070.