1 |
Alemi, F., Kwon, E., Poole, D. P., Lieu, T., Lyo, V., Cattaruzza, F., Cevikbas, F., Steinhoff, M., Nassini, R., Materazzi, S., Guerrero-Alba, R., Valdez-Morales, E., Cottrell, G. S., Schoonjans, K., Geppetti, P., Vanner, S. J., Bunnett, N. W. and Corvera, C. U. (2013) The TGR5 receptor mediates bile acid-induced itch and analgesia. J. Clin. Invest. 123, 1513-1530.
DOI
|
2 |
Azimi, E., Reddy, V. B., Pereira, P. J. S., Talbot, S., Woolf, C. J. and Lerner, E. A. (2017) Substance P activates Mas-related G protein-coupled receptors to induce itch. J. Allergy Clin. Immunol. 140, 447-453.e3.
DOI
|
3 |
Azimi, E., Reddy, V. B., Shade, K. C., Anthony, R. M., Talbot, S., Pereira, P. J. S. and Lerner, E. A. (2016) Dual action of neurokinin-1 antagonists on Mas-related GPCRs. JCI Insight 1, e89362.
|
4 |
Carey, J. B., Jr., Wilson, I. D., Zaki, F. G. and Hanson, R. F. (1966) The metabolism of bile acids with special reference to liver injury. Medicine (Baltimore) 45, 461-470.
DOI
|
5 |
Meixiong, J., Vasavda, C., Snyder, S. H. and Dong, X. (2019c) MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus. Proc. Natl. Acad. Sci. U.S.A. 116, 10525-10530.
DOI
|
6 |
Pradhananga, S. and Shim, W. S. (2015) Caffeic acid exhibits antipruritic effects by inhibition of multiple itch transmission pathways in mice. Eur. J. Pharmacol. 762, 313-321.
DOI
|
7 |
Staudinger, J. L., Goodwin, B., Jones, S. A., Hawkins-Brown, D., MacKenzie, K. I., LaTour, A., Liu, Y., Klaassen, C. D., Brown, K. K., Reinhard, J., Willson, T. M., Koller, B. H. and Kliewer, S. A. (2001) The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Proc. Natl. Acad. Sci. U.S.A. 98, 3369-3374.
DOI
|
8 |
Thakare, R., Alamoudi, J. A., Gautam, N., Rodrigues, A. D. and Alnouti, Y. (2018) Species differences in bile acids I. Plasma and urine bile acid composition. J. Appl. Toxicol. 38, 1323-1335.
DOI
|
9 |
Tsvilovskyy, V., Solis-Lopez, A., Ohlenschlager, K. and Freichel, M. (2018) Isolation of peritoneum-derived mast cells and their functional characterization with Ca2+-imaging and degranulation assays. J. Vis. Exp. (137), 57222.
|
10 |
Xu, G., Dai, M., Zheng, X., Lin, H., Liu, A. and Yang, J. (2020) Cholestatic models induced by lithocholic acid and alphanaphthylisothiocyanate: different etiological mechanisms for liver injury but shared JNK/STAT3 signaling. Mol. Med. Rep. 22, 1583-1593.
DOI
|
11 |
Dong, X., Han, S., Zylka, M. J., Simon, M. I. and Anderson, D. J. (2001) A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Cell 106, 619-632.
DOI
|
12 |
Jeong, J. Y., Yim, H. S., Ryu, J. Y., Lee, H. S., Lee, J. H., Seen, D. S. and Kang, S. G. (2012) One-step sequence- and ligation-independent cloning as a rapid and versatile cloning method for functional genomics studies. Appl. Environ. Microbiol. 78, 5440-5443.
DOI
|
13 |
Meixiong, J., Anderson, M., Limjunyawong, N., Sabbagh, M. F., Hu, E., Mack, M. R., Oetjen, L. K., Wang, F., Kim, B. S. and Dong, X. (2019a) Activation of mast-cell-expressed mas-related G-proteincoupled receptors drives non-histaminergic itch. Immunity 50, 1163-1171.e5.
DOI
|
14 |
Sanjel, B. and Shim, W. S. (2020) Recent advances in understanding the molecular mechanisms of cholestatic pruritus: a review. Biochim. Biophys. Acta Mol. Basis Dis. 1866, 165958.
DOI
|
15 |
Tan, K. P., Wood, G. A., Yang, M. and Ito, S. (2010) Participation of nuclear factor (erythroid 2-related), factor 2 in ameliorating lithocholic acid-induced cholestatic liver injury in mice. Br. J. Pharmacol. 161, 1111-1121.
DOI
|
16 |
Yu, H., Zhao, T., Liu, S., Wu, Q., Johnson, O., Wu, Z., Zhuang, Z., Shi, Y., Peng, L., He, R., Yang, Y., Sun, J., Wang, X., Xu, H., Zeng, Z., Zou, P., Lei, X., Luo, W. and Li, Y. (2019) MRGPRX4 is a bile acid receptor for human cholestatic itch. Elife 8, e48431.
DOI
|
17 |
Woolbright, B. L., Li, F., Xie, Y., Farhood, A., Fickert, P., Trauner, M. and Jaeschke, H. (2014) Lithocholic acid feeding results in direct hepato-toxicity independent of neutrophil function in mice. Toxicol. Lett. 228, 56-66.
DOI
|
18 |
Han, S. K., Dong, X., Hwang, J. I., Zylka, M. J., Anderson, D. J. and Simon, M. I. (2002) Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway. Proc. Natl. Acad. Sci. U.S.A. 99, 14740-14745.
DOI
|
19 |
Ridlon, J. M., Harris, S. C., Bhowmik, S., Kang, D. J. and Hylemon, P. B. (2016) Consequences of bile salt biotransformations by intestinal bacteria. Gut Microbes 7, 22-39.
DOI
|
20 |
Subramanian, H., Gupta, K. and Ali, H. (2016) Roles of Mas-related G protein-coupled receptor X2 on mast cell-mediated host defense, pseudoallergic drug reactions, and chronic inflammatory diseases. J. Allergy Clin. Immunol. 138, 700-710.
DOI
|
21 |
Chen, J., Zhao, K. N. and Chen, C. (2014) The role of CYP3A4 in the biotransformation of bile acids and therapeutic implication for cholestasis. Ann. Transl. Med. 2, 7.
|
22 |
Cipriani, S., Renga, B., D'Amore, C., Simonetti, M., De Tursi, A. A., Carino, A., Monti, M. C., Sepe, V., Zampella, A. and Fiorucci, S. (2015) Impaired itching perception in murine models of cholestasis is supported by dysregulation of GPBAR1 signaling. PLoS ONE 10, e0129866.
DOI
|
23 |
Fickert, P., Fuchsbichler, A., Marschall, H. U., Wagner, M., Zollner, G., Krause, R., Zatloukal, K., Jaeschke, H., Denk, H. and Trauner, M. (2006) Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice. Am. J. Pathol. 168, 410-422.
DOI
|
24 |
Fisher, M. M., Magnusson, R. and Miyai, K. (1971) Bile acid metabolism in mammals. I. Bile acid-induced intrahepatic cholestasis. Lab. Invest. 25, 88-91.
|
25 |
Islam, M. N., Lee, K. W., Yim, H. S., Lee, S. H., Jung, H. C., Lee, J. H. and Jeong, J. Y. (2017) Optimizing T4 DNA polymerase conditions enhances the efficiency of one-step sequence- and ligationindependent cloning. Biotechniques 63, 125-130.
DOI
|
26 |
Green, D. P., Limjunyawong, N., Gour, N., Pundir, P. and Dong, X. (2019) A mast-cell-specific receptor mediates neurogenic inflammation and pain. Neuron 101, 412-420.e3.
DOI
|
27 |
Perner, C., Flayer, C. H., Zhu, X., Aderhold, P. A., Dewan, Z. N. A., Voisin, T., Camire, R. B., Chow, O. A., Chiu, I. M. and Sokol, C. L. (2020) Substance P release by sensory neurons triggers dendritic cell migration and initiates the type-2 immune response to allergens. Immunity 53, 1063-1077.e7.
DOI
|
28 |
Lay, M. and Dong, X. (2020) Neural mechanisms of itch. Annu. Rev. Neurosci. 43, 187-205.
DOI
|
29 |
McNeil, B. D., Pundir, P., Meeker, S., Han, L., Undem, B. J., Kulka, M. and Dong, X. (2015) Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions. Nature 519, 237-241.
DOI
|
30 |
Meixiong, J., Vasavda, C., Green, D., Zheng, Q., Qi, L., Kwatra, S. G., Hamilton, J. P., Snyder, S. H. and Dong, X. (2019b) Identification of a bilirubin receptor that may mediate a component of cholestatic itch. Elife 8, e44116.
DOI
|