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http://dx.doi.org/10.4062/biomolther.2016.187

Therapeutic Potential of Medicinal Plants and Their Constituents on Lung Inflammatory Disorders  

Kim, Hyun Pyo (College of Pharmacy, Kangwon National University)
Lim, Hyun (College of Pharmacy, Kangwon National University)
Kwon, Yong Soo (College of Pharmacy, Kangwon National University)
Publication Information
Biomolecules & Therapeutics / v.25, no.2, 2017 , pp. 91-104 More about this Journal
Abstract
Acute bronchitis and chronic obstructive pulmonary diseases (COPD) are essentially lung inflammatory disorders. Various plant extracts and their constituents showed therapeutic effects on several animal models of lung inflammation. These include coumarins, flavonoids, phenolics, iridoids, monoterpenes, diterpenes and triterpenoids. Some of them exerted inhibitory action mainly by inhibiting the mitogen-activated protein kinase pathway and nuclear transcription $factor-{\kappa}B$ activation. Especially, many flavonoid derivatives distinctly showed effectiveness on lung inflammation. In this review, the experimental data for plant extracts and their constituents showing therapeutic effectiveness on animal models of lung inflammation are summarized.
Keywords
Medicinal plant; Lung inflammation; COPD; Constituent; Flavonoid;
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