Browse > Article
http://dx.doi.org/10.4062/biomolther.2014.083

Lightening up Light Therapy: Activation of Retrograde Signaling Pathway by Photobiomodulation  

Kim, Hong Pyo (Ajou University, School of Pharmacy)
Publication Information
Biomolecules & Therapeutics / v.22, no.6, 2014 , pp. 491-496 More about this Journal
Abstract
Photobiomodulation utilizes monochromatic (or quasimonochromatic) light in the electromagnetic region of 600~1000 nm for the treatment of soft tissues in a nondestructive and nonthermal mode. It is conceivable that photobiomodulation is based upon the ability of the light to alter cell metabolism as it is absorbed by general hemoproteins and cytochrome c oxidase (COX) in particular. Recently it has been suggested radiation of visible and infrared (IR) activates retrograde signaling pathway from mitochondria to nucleus. In this review, the role of COX in the photobiomodulation will be discussed. Further a possible role of water as a photoreceptor will be suggested.
Keywords
Photobiomodulation; Hemoprotein; Cytochrome c oxidase; Retrograde signaling; Water;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Abergel, R. P., Meeker, C. A., Lam, T. S., Dwyer, R. M., Lesavoy, M. A. and Uitto, J. (1984) Control of connective tissue metabolism by lasers: recent developments and future prospects. J. Am. Acad. Dermatol. 11, 1142-1150.   DOI
2 Carroll, J. D., Milward, M. R., Cooper, P. R., Hadis, M., and Pain, W. M. (2014) Developments in low level light therapy (LLLT) for dentistry. Dent. Mater. 30, 465-475.   DOI
3 Chen, W. W., Birsoy, K., Mihaylova, M. M., Snitkin, H., Stasinski, I., Yucel, B., Bayraktar, E. C., Carette, J. E., Clish, C. B., Brummelkamp, T. R., Sabatini, D. D. and Sabatini, D. M. (2014) Inhibition of ATPIF1 ameliorates severe mitochondrial respiratory chain dysfunction in mammalian cells. Cell Rep. 7, 27-34.   DOI
4 Conlan, M. J., Rapley, J. W. and Cobb, C. M. (1996) Biostimulation of wound healing by low-energy laser irradiation. A review. J. Clin. Periodontol. 23, 492-496.   DOI   ScienceOn
5 Curcio, J. A. and Petty, C. C. (1951) The near infrared absorption spectrum of liquid water. J. Optic. Soc. Am. 41, 302-304.   DOI
6 Divakaruni, A. S., Wiley, S. E., Rogers, G. W., Andreyev, A. Y., Petrosyan, S., Loviscach, M., Wall, E. A., Yadava, N., Heuck, A. P., Ferrick, D. A., Henry, R. R., McDonald, W. G., Colca, J. R., Simon, M. I., Ciaraldi, T. P. and Murphy, A. N. (2013) Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier. Proc. Natl. Acad. Sci. U S A. 110, 5422-5427.   DOI
7 Eells, J. T., Henry, M. M., Summerfelt, P., Wong-Riley, M. T., Buchmann, E. V., Kane, M., Whela, N. T. and Whelan, H. T. (2003) Therapeutic photobiomodulation for methanol-induced retinal toxicity. Proc. Natl. Acad. Sci. U S A. 100, 3439-3444.   DOI
8 Korolnek, T. and Hamza I. (2014) Like iron in the blood of the people: the requirement for heme trafficking in iron metabolism. Front. Pharmacol. 5, 126.
9 Karu, T. I. (2008) Mitochondrial signaling in mammalian cells activated by red and near IR radiation. Photochem. Photobiol. 84, 1091-1099.   DOI
10 Kim, H. P., Ryter, S. W. and Choi, A. M. (2006) CO as a cellular signaling molecule. Annu. Rev. Pharmacol. Toxicol. 46, 411-449.   DOI   ScienceOn
11 Lane, N. (2006) Power games. Nature 443, 901-903.   DOI
12 Lee, G., Wong, E. and Mason, D. T. (1996) New concepts in pain management and in the application of low-power laser for relief of cervicothoracic pain syndromes. Am. Heart J. 132, 1329-1334.   DOI
13 Lee, S. J., Zhang, J., Choi, A. M. and Kim, H. P. (2013) Mitochondrial dysfunction induces formation of lipid droplets as a generalized response to stress. Oxid. Med. Cell. Longev. 2013, 327167.
14 Mester, E., Mester, A. F. and Mester, A. (1985) The biomedical effects of laser application. Lasers Surg. Med. 5, 31-39.   DOI   ScienceOn
15 Mester, E., Spiry, T., Szende, B. and Tota, J. G. (1971) Effect of laser rays on wound healing. Am. J. Surg. 122, 532-535.   DOI   ScienceOn
16 Moncada, S. and Bolanos, J. P. (2006) Nitric oxide, cell bioenergetics and neurodegeneration. J. Neurochem. 97, 1676-1689.   DOI
17 Munro, A. W., Girvan, H. M., McLean, K. J., Cheesman, M. R. and Leys, D. (2009) Heme and Hemoproteins, In Tetrapyrrole: Birth, Life and death (M. J. Warren and A. G. Smith, Ed.), pp 160-183. Landes Bioscience and Springer Science, Austin.
18 Rochkind, S., Geun, S. and Shainberg, A. (2013) Phototherapy and nerve injury: focus on muscle response. Int. Rev. Neurobiol. 109, 99-109.   DOI
19 Park, J. H., Lee, S., Cho, D. H., Park, Y. M., Kang, D. H. and Jo, I. (2013) Far-infrared radiation acutely increases nitric oxide production by increasing Ca(2+) mobilization and Ca(2+)/calmodulin-dependent protein kinase II-mediated phosphorylation of endothelial nitric oxide synthase at serine 1179. Biochem. Biophys. Res. Commun. 436, 601-606.   DOI
20 Pollack, G. H. (2013) The fourth phase of water. Ebner & Sons publishers, Seattle.
21 Quirk, B. J., Desmet, K. D., Henry, M., Buchmann, E., Wong-Riley, M., Eells, J. T. and Whelan, H. T. (2012) Therapeutic effect of near infrared (NIR) light on Parkinson's disease models. Front. Biosci. 4, 818-823.
22 Reddy, G. K., Stehno-Bittel, L. and Enwemeka, C. S. (2001) Laser photostimulation accelerates wound healing in diabetic rats. Wound Repair Regen. 9, 248-255.   DOI   ScienceOn
23 Rich, P. R. and Iwaki, M. (2007) A comparison of catalytic site intermediates of cytochrome c oxidase and peroxidases. Biochemistry (Moscow) 72, 1047-1055.   DOI
24 Santana-Blank, L., Rodriguez-Santana, E., Santana-Rodriguez, K. E. (2013) Photobiomodulation of aqueous interfaces: finding evidence to support the exclusion zone in experimental and clinical studies. Photomed. Laser Surg. 31, 461-462.   DOI
25 Schindl, A., Schindl, M., Pernerstorfer-Schon, H. and Schindl, L. (2000) Low-intensity laser therapy: a review. J. Investig. Med. 48, 312-326.
26 Whelan, H. T., Buchmann, E. V., Dhokalia, A., Kane, M. P., Whelan, N. T., Wong-Riley, M. T., Eells, J. T., Gould, L. J., Hammamieh, R., Das, R. and Jett, M. (2003) Effect of NASA light-emitting diode irradiation on molecular changes for wound healing in diabetic mice. J. Clin. Laser Med. Surg. 21, 67-74.   DOI
27 Slebos, D. J., Ryter, S. W., van der Toorn, M., Liu, F., Guo, F., Baty, C. J., Karlsson, J. M., Watkins, S. C., Kim, H. P., Wang, X., Lee, J. S., Postma, D. S., Kauffman, H. F. and Choi, A. M. (2007) Mitochondrial localization and function of heme oxygenase-1 in cigarette smoke-induced cell death. Am. J. Respir. Cell Mol. Biol. 36, 409-417.   DOI
28 Tanaka, Y., Matsuo, K., Yuzuriha, S., Yan, H. and Nakayama, J. (2010) Non-thermal cytocidal effect of infrared irradiation on cultured cancer cells using specialized device. Cancer Sci. 101, 1396-1402.   DOI
29 Wedlock, P., Shephard, R. A., Little, C. and McBurney, F. (1996) Analgesic effects of cranial laser treatment in two rat nociception models. Physiol. Behav. 59, 445-448.   DOI
30 Wong-Riley, M. T., Bai, X., Buchmann, E. and Whelan, H. T. (2001) Light-emitting diode treatment reverses the effect of TTX on cytochrome oxidase in neurons. Neuroreport 12, 3033-3037.   DOI   ScienceOn
31 Wong-Riley, M. T., Liang, H. L., Eells, J. T., Chance, B., Henry, M. M., Buchmann, E., Kane, M. and Whelan, H. T. (2005) Photobiomodulation directly benefits primary neurons functionally inactivated by toxins: role of cytochrome c oxidase. J. Biol. Chem. 280, 4761-4771.   DOI   ScienceOn
32 Yaakobi, T., Maltz, L. and Oron, U. (1996) Promotion of bone repair in the cortical bone of the tibia in rats by low energy laser (He-Ne) irradiation. Calcif. Tissue Int. 59, 297-300.   DOI   ScienceOn
33 Zaobornyj, T. and Ghafourifar, P. (2012) Strategic localization of heart mitochondrial NOS: a review of the evidence. Am. J. Physiol. Heart Circ. Physiol. 303, H1283-1293.   DOI
34 Ying, R., Liang, H. L., Whelan, H. T., Eells, J. T. and Wong-Riley, M. T. (2008) Pretreatment with near-infrared light via light-emitting diode provides added benefit against rotenone- and MPP+-induced neurotoxicity. Brain Res. 1243, 167-173.   DOI
35 Zhang, Y., Song, S., Fong, C. C., Tsang, C. H., Yang, Z. and Yang, M. (2003) cDNA microarray analysis of gene expression profiles in human fibroblast cells irradiated with red light. J. Invest. Dermatol. 120, 849-857.   DOI
36 Zuckerbraun, B. S., Chin, B. Y., Bilban, M., d'Avila, J. C., Rao, J., Billiar, T. R. and Otterbein, L. E. (2007) Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mitochondrial reactive oxygen species. FASEB J. 21, 1099-1106.   DOI
37 Desmet, K. D., Paz, D. A., Corry, J. J., Eells, J. T., Wong-Riley, M. T., Henry, M. M., Buchmann, E. V., Connelly, M. P., Dovi, J. V., Liang, H. L., Henshel, D. S., Yeager, R. L., Millsap, D. S., Lim, J., Gould, L. J., Das, R., Jett, M., Hodgson, B. D., Margolis, D. and Whelan, H. T. (2006) Clinical and experimental applications of NIR-LED photobiomodulation. Photomed. Laser Surg. 24, 121-128.   DOI   ScienceOn
38 Eells, J. T., Wong-Riley, M. T., VerHoeve, J., Henry, M., Buchman, E. V., Kane, M. P., Gould, L. J., Das, R., Jett, M., Hodgson, B. D., Margolis, D. and Whelan, H. T. (2004) Mitochondrial signal transduction in accelerated wound and retinal healing by near-infrared light therapy. Mitochondrion 4, 559-567.   DOI   ScienceOn