1 |
Chang, J., Yang, S. H., Cho, Y. G., Hwang, S. B., Hahn, Y. S. and Sung, Y. C. (1998) Hepatitis C virus core from two different genotypes has an oncogenic potential but is not sufficient for transforming primary rat embryo fibroblasts in cooperation with the H-ras oncogene. J. Virol. 72, 3060-3065.
|
2 |
Chang, K. S., Jiang, J., Cai, Z. and Luo, G. (2007) Human apolipoprotein e is required for infectivity and production of hepatitis C virus in cell culture. J. Virol. 81, 13783-13793.
DOI
ScienceOn
|
3 |
Cocquerel, L., Duvet, S., Meunier, J. C., Pillez, A., Cacan, R., Wychowski, C. and Dubuisson, J. (1999) The transmembrane domain of hepatitis C virus glycoprotein E1 is a signal for static retention in the endoplasmic reticulum. J. Virol. 73, 2641-2649.
|
4 |
Cocquerel, L., Meunier, J. C., Pillez, A., Wychowski, C. and Dubuisson, J. (1998) A retention signal necessary and sufficient for endoplasmic reticulum localization maps to the transmembrane domain of hepatitis C virus glycoprotein E2. J. Virol. 72, 2183-2191.
|
5 |
Coller, K. E., Heaton, N. S., Berger, K. L., Cooper, J. D., Saunders, J. L. and Randall, G. (2012) Molecular determinants and dynamics of hepatitis C virus secretion. PLoS Pathog. 8, e1002466.
DOI
|
6 |
Di Bisceglie, A. M. (2000) Natural history of hepatitis C: its impact on clinical management. Hepatology 31, 1014-1018.
DOI
ScienceOn
|
7 |
Fukasawa, M. (2010) Cellular lipid droplets and hepatitis C virus life cycle. Biol. Pharm. Bull. 33, 355-359.
DOI
ScienceOn
|
8 |
Grakoui, A., McCourt, D. W., Wychowski, C., Feinstone, S. M. and Rice, C. M. (1993a) A second hepatitis C virus-encoded proteinase. Proc. Natl. Acad. Sci. U.S.A. 90, 10583-10587.
DOI
ScienceOn
|
9 |
Grakoui, A., Wychowski, C., Lin, C., Feinstone, S. M. and Rice, C. M. (1993b) Expression and identification of hepatitis C virus polyprotein cleavage products. J. Virol. 67, 1385-1395.
|
10 |
Heim, M. H., Moradpour, D. and Blum, H. E. (1999) Expression of hepatitis C virus proteins inhibits signal transduction through the Jak-STAT pathway. J. Virol. 73, 8469-8475.
|
11 |
Hosui, A., Ohkawa, K., Ishida, H., Sato, A., Nakanishi, F., Ueda, K., Takehara, T., Kasahara, A., Sasaki, Y., Hori, M. and Hayashi, N. (2003) Hepatitis C virus core protein differently regulates the JAK-STAT signaling pathway under interleukin-6 and interferon-gamma stimuli. J. Biol. Chem. 278, 28562-28571.
DOI
ScienceOn
|
12 |
Huang, H., Sun, F., Owen, D. M., Li, W., Chen, Y., Gale, M. Jr. and Ye, J. (2007) Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins. Proc. Natl. Acad. Sci. U.S.A. 104, 5848-5853.
DOI
ScienceOn
|
13 |
Ihle, J. N. (1996) STATs: signal transducers and activators of transcription. Cell 84, 331-334.
DOI
ScienceOn
|
14 |
Aaronson, D. S. and Horvath, C. M. (2002) A road map for those who don't know JAK-STAT. Science 296, 1653-1655.
DOI
ScienceOn
|
15 |
Alter, M. J., Kruszon-Moran, D., Nainan, O. V., McQuillan, G. M., Gao, F., Moyer, L. A., Kaslow, R. A. and Margolis, H. S. (1999) The prevalence of hepatitis C virus infection in the United States, 1988 through 1994. N. Engl. J. Med. 341, 556-562.
DOI
ScienceOn
|
16 |
Bach, E. A., Aguet, M. and Schreiber, R. D. (1997) The IFN gamma receptor: a paradigm for cytokine receptor signaling. Annu. Rev. Immunol. 15, 563-591.
DOI
ScienceOn
|
17 |
Barba, G., Harper, F., Harada, T., Kohara, M., Goulinet, S., Matsuura, Y., Eder, G., Schaff, Z., Chapman, M. J., Miyamura, T. and Brechot, C. (1997) Hepatitis C virus core protein shows a cytoplasmic localization and associates to cellular lipid storage droplets. Proc. Natl Acad. Sci. U.S.A. 94, 1200-1205.
DOI
ScienceOn
|
18 |
Basu, A., Meyer, K., Ray, R. B. and Ray, R. (2001) Hepatitis C virus core protein modulates the interferon-induced transacting factors of Jak/Stat signaling pathway but does not affect the activation of downstream IRF-1 or 561 gene. Virology 288, 379-390.
|
19 |
Rouille, Y., Helle, F., Delgrange, D., Roingeard, P., Voisset, C., Blanchard, E., Belouzard, S., McKeating, J., Patel, A. H., Maertens, G., Wakita, T., Wychowski, C. and Dubuisson, J. (2006) Subcellular localization of hepatitis C virus structural proteins in a cell culture system that efficiently replicates the virus. J. Virol. 80, 2832-2841.
DOI
ScienceOn
|
20 |
Blight, K. J., Kolykhalov, A. A. and Rice, C. M. (2000) Efficient initiation of HCV RNA replication in cell culture. Science 290, 1972-1974.
DOI
ScienceOn
|
21 |
Shepard, C. W., Finelli, L. and Alter, M. J. (2005) Global epidemiology of hepatitis C virus infection. Lancet Infect. Dis. 5, 558-567.
DOI
ScienceOn
|
22 |
Sklan, E. H., Staschke, K., Oakes, T. M., Elazar, M., Winters, M., Aroeti, B., Danieli, T. and Glenn, J. S. (2007) A Rab-GAP TBC domain protein binds hepatitis C virus NS5A and mediates viral replication. J. Virol. 81, 11096-11105.
DOI
ScienceOn
|
23 |
Tscherne, D. M., Jones, C. T., Evans, M. J., Lindenbach, B. D., McKeating, J. A. and Rice, C. M. (2006) Time- and temperature-dependent activation of hepatitis C virus for low-pH-triggered entry. J. Virol. 80, 1734-1741.
DOI
ScienceOn
|
24 |
Liang, T. J., Rehermann, B., Seeff, L. B. and Hoofnagle, J. H. (2000) Pathogenesis, natural history, treatment, and prevention of hepatitis C. Ann. Intern. Med. 132, 296-305.
DOI
ScienceOn
|
25 |
Zeuzem, S., Feinman, S. V., Rasenack, J., Heathcote, E. J., Lai, M. Y., Gane, E., O'Grady, J., Reichen, J., Diago, M., Lin, A., Hoffman, J. and Brunda, M. J. (2000) Peginterferon alfa-2a in patients with chronic hepatitis C. N. Engl. J. Med. 343, 1666-1672.
DOI
ScienceOn
|
26 |
Lee, C. (2011) Discovery of hepatitis C virus NS5A inhibitors as a new class of anti-HCV therapy. Arch. Pharm. Res. 34, 1403-1407.
DOI
ScienceOn
|
27 |
Lee, C. and Laimins, L. A. (2004) Role of the PDZ domain-binding motif of the oncoprotein E6 in the pathogenesis of human papillomavirus type 31. J. Virol. 78, 12366-12377.
DOI
ScienceOn
|
28 |
Lindenbach, B. D., Evans, M. J., Syder, A. J., Wolk, B., Tellinghuisen, T. L., Liu, C. C., Maruyama, T., Hynes, R. O., Burton, D. R., McKeating, J. A. and Rice, C. M. (2005) Complete replication of hepatitis C virus in cell culture. Science 309, 623-626.
DOI
ScienceOn
|
29 |
Lohmann, V., Korner, F., Koch, J., Herian, U., Theilmann, L. and Bartenschlager, R. (1999) Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line. Science 285, 110-113.
DOI
ScienceOn
|
30 |
Luquin, E., Larrea, E., Civeira, M. P., Prieto, J. and Aldabe, R. (2007) HCV structural proteins interfere with interferon-alpha Jak/STAT signalling pathway. Antiviral Res. 76, 194-197.
DOI
ScienceOn
|
31 |
Miyanari, Y., Atsuzawa, K., Usuda, N., Watashi, K., Hishiki, T., Zayas, M., Bartenschlager, R., Wakita, T., Hijikata, M. and Shimotohno, K. (2007) The lipid droplet is an important organelle for hepatitis C virus production. Nat. Cell Biol. 9, 1089-1097.
DOI
ScienceOn
|
32 |
Moradpour, D., Penin, F. and Rice, C. M. (2007) Replication of hepatitis C virus. Nat. Rev. Microbiol. 5, 453-463.
DOI
ScienceOn
|
33 |
Ray, R. B., Meyer, K., Steele, R., Shrivastava, A., Aggarwal, B. B. and Ray, R. (1998) Inhibition of tumor necrosis factor (TNF-alpha)-mediated apoptosis by hepatitis C virus core protein. J. Biol. Chem. 273, 2256-2259.
DOI
ScienceOn
|
34 |
Moriya, K., Fujie, H., Shintani, Y., Yotsuyanagi, H., Tsutsumi, T., Ishibashi, K., Matsuura, Y., Kimura, S., Miyamura, T. and Koike, K. (1998) The core protein of hepatitis C virus induces hepatocellular carcinoma in transgenic mice. Nat. Med. 4, 1065-1067.
DOI
ScienceOn
|
35 |
Pawlotsky, J. M. (2011) The results of Phase III clinical trials with telaprevir and boceprevir presented at the Liver Meeting 2010: a new standard of care for hepatitis C virus genotype 1 infection, but with issues still pending. Gastroenterology 140, 746-754.
DOI
ScienceOn
|
36 |
Ray, R. B., Lagging, L. M., Meyer, K. and Ray, R. (1996) Hepatitis C virus core protein cooperates with ras and transforms primary rat embryo fibroblasts to tumorigenic phenotype. J. Virol. 70, 4438-4443.
|
37 |
Roingeard, P., Hourioux, C., Blanchard, E. and Prensier, G. (2008) Hepatitis C virus budding at lipid droplet-associated ER membrane visualized by 3D electron microscopy. Histochem. Cell Biol. 130, 561-566.
DOI
|
38 |
Jiang, J. and Luo, G. (2009) Apolipoprotein E but not B is required for the formation of infectious hepatitis C virus particles. J. Virol. 83, 12680-12691.
DOI
ScienceOn
|
39 |
Jones, D. M. and McLauchlan, J. (2010) Hepatitis C virus: assembly and release of virus particles. J. Biol. Chem. 285, 22733-22739.
DOI
ScienceOn
|
40 |
Blight, K. J., McKeating, J. A. and Rice, C. M. (2002) Highly permissive cell lines for subgenomic and genomic hepatitis C virus RNA replication. J. Virol. 76, 13001-13014.
DOI
ScienceOn
|
41 |
Boehm, U., Klamp, T., Groot, M. and Howard, J. C. (1997) Cellular responses to interferon-gamma. Annu. Rev. Immunol. 15, 749-795.
DOI
ScienceOn
|