Influence of Environmental Conditions on c-Jun N-terminal Kinase Mediated Apoptosis of HL60 Cells by Anti-Cancer Drugs |
Hur, Eun-Hye
(Department of Hematology, Asan Medical Center, University of Ulsan College of Medicine)
Kang, Mun-Jung (Department of Hematology, Asan Medical Center, University of Ulsan College of Medicine) Kim, Sung-Doo (Department of Hematology, Asan Medical Center, University of Ulsan College of Medicine) Lim, Sung-Nam (Department of Hematology, Asan Medical Center, University of Ulsan College of Medicine) Kim, Dae-Young (Department of Hematology, Asan Medical Center, University of Ulsan College of Medicine) Lee, Jung-Hee (Department of Hematology, Asan Medical Center, University of Ulsan College of Medicine) Lee, Kyoo-Hyung (Department of Hematology, Asan Medical Center, University of Ulsan College of Medicine) Lee, Je-Hwan (Department of Hematology, Asan Medical Center, University of Ulsan College of Medicine) |
1 | Cripe, L. D., Gelfanov, V. M., Smith, E. A., Spigel, D. R., Phillips, C. A., Gabig, T. G., Jung, S. H., Fyffe, J., Hartman, A. D., Kneebone, P., Mercola, D., Burgess, G. S. and Boswell, H. S. (2002). Role for c-jun N-terminal kinase in treatmentrefractory acute myeloid leukemia (AML): signaling to multidrug-efflux and hyperproliferation. Leukemia 16, 799-812. DOI |
2 | Potapova, O., Haghighi, A., Bost, F., Liu, C., Birrer, M. J., Gjerset, R. and Mercola, D. (1997). The Jun kinase/stressactivated protein kinase pathway functions to regulate DNA repair and inhibition of the pathway sensitizes tumor cells to cisplatin. J. Biol. Chem. 272, 14041-14044. DOI |
3 | Sampath, D., Cortes, J., Estrov, Z., Du, M., Shi, Z., Andreeff, M., Gandhi, V. and Plunkett, W. (2006). Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial. Blood 107, 2517-2524. DOI |
4 | Sampath, D. and Plunkett, W. (2000). The role of c-Jun kinase in the apoptotic response to nucleoside analogue-induced DNA damage. Cancer Res. 60, 6408-6415. |
5 | Stadheim, T.A., Saluta, G.R. and Kucera, G.L. (2000). Role of c-Jun N-terminal kinase/p38 stress signaling in 1-beta-Darabinofuranosylcytosine-induced apoptosis. Biochem. Pharmacol. 59, 407-418. DOI |
6 | Tashiro, E., Simizu, S., Takada, M., Umezawa, K. and Imoto, M. (1998). Caspase-3 activation is not responsible for vinblastine-induced Bcl-2 phosphorylation and G2/M arrest in human small cell lung carcinoma Ms-1 cells. Jpn. J. Cancer Res. 89, 940-946. DOI |
7 | Herr, I. and Debatin, K.M. (2001). Cellular stress response and apoptosis in cancer therapy. Blood 98, 2603-2614. DOI |
8 | Johnson, G. L. and Nakamura, K. (2007). The c-jun kinase/stress- activated pathway: regulation, function and role in human disease. Biochim. Biophys. Acta 1773, 1341-1348. DOI |
9 | Jost, L. M., Kirkwood, J. M. and Whiteside, T. L. (1992). Improved short- and long-term XTT-based colorimetric cellular cytotoxicity assay for melanoma and other tumor cells. J. Immunol. Methods 147, 153-165. DOI ScienceOn |
10 | Panaretakis, T., Laane, E., Pokrovskaja, K., Bjorklund, A. C., Moustakas, A., Zhivotovsky, B., Heyman, M., Shoshan, M. C. and Grander, D. (2005). Doxorubicin requires the sequential activation of caspase-2, protein kinase Cdelta, and c-Jun NH2-terminal kinase to induce apoptosis. Mol. Biol. Cell. 16, 3821-3831. DOI |
11 | Yu, R., Shtil, A. A., Tan, T. H., Roninson, I. B. and Kong, A. N. (1996). Adriamycin activates c-jun N-terminal kinase in human leukemia cells: a relevance to apoptosis. Cancer Lett. 107, 73-81. DOI |
12 | Philchenkov, A. (2004). Caspases: potential targets for regulating cell death. J. Cell. Mol. Med. 8, 432-444. DOI |
13 | Potapova, O., Gorospe, M., Dougherty, R. H., Dean, N. M., Gaarde, W. A. and Holbrook, N. J. (2000). Inhibition of c-Jun N-terminal kinase 2 expression suppresses growth and induces apoptosis of human tumor cells in a p53-dependent manner. Mol. Cell. Biol. 20, 1713-1722. DOI |
14 | Turnbull, K. J., Brown, B. L. and Dobson, P. R. (1999). Caspase-3-like activity is necessary but not sufficient for daunorubicin-induced apoptosis in Jurkat human lymphoblastic leukemia cells. Leukemia 13, 1056-1061. DOI |
15 | Weston, C. R. and Davis, R. J. (2007). The JNK signal transduction pathway. Curr. Opin. Cell. Biol. 19, 142-149. DOI |
16 | Wisdom, R., Johnson, R. S. and Moore, C. (1999). c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms. EMBO J. 18, 188-197. DOI ScienceOn |
17 | Choi, J. H. and Lee, K. T. (2009). Costunolide-induced apoptosis in human leukemia cells: involvement of c-jun N-terminal kinase activation. Biol. Pharm. Bull. 32, 1803-1808. DOI |
18 | Benjamin, C. W., Hiebsch, R. R. and Jones, D. A. (1998). Caspase activation in MCF7 cells responding to etoposide treatment. Mol. Pharmacol. 53, 446-450. DOI |
19 | Boldt, S., Weidle, U. H. and Kolch, W. (2002). The role of MAPK pathways in the action of chemotherapeutic drugs. Carcinogenesis. 23, 1831-1838. |
20 | Brantley-Finley, C., Lyle, C. S., Du, L., Goodwin, M. E., Hall, T., Szwedo, D., Kaushal, G. P. and Chambers, T. C. (2003). The JNK, ERK and p53 pathways play distinct roles in apoptosis mediated by the antitumor agents vinblastine, doxorubicin, and etoposide. Biochem. Pharmacol. 66, 459-469. DOI |
21 | Cui, J., Zhang, M., Zhang, Y.Q. & Xu, Z. H. (2007). JNK pathway: diseases and therapeutic potential. Acta Pharmacol. Sin. 28, 601-608. DOI |
22 | Davis, R. J. (2000). Signal transduction by the JNK group of MAP kinases. Cell 103, 239-252. DOI |
23 | Dhanasekaran, D. N. and Reddy, E. P. (2008). JNK signaling in apoptosis. Oncogene 27, 6245-6251. DOI |
24 | Do, J. H., Oh, S. H., Song, E. J., Chung, J. S., Kang, C. D. and Lee, E. Y. (2007). Treatment outcome of multidrug resistance related mRNA expression and c-jun-N-terminal kinase activity in patients with acute myeloid leukemia. Korean J. Lab. Med. 27, 229-236. DOI |
25 | Fan, M. and Chambers, T. C. (2001). Role of mitogen-activated protein kinases in the response of tumor cells to chemotherapy. Drug Resist. Updat. 4, 253-267. DOI |
26 | Fan, M., Goodwin, M. E., Birrer, M. J. & Chambers, T. C. (2001). The c-Jun NH(2)-terminal protein kinase/AP-1 pathway is required for efficient apoptosis induced by vinblastine. Cancer Res. 61, 4450-4458. |
27 | Krishan, A. (1975). Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining. J. Cell. Biol. 66, 188-193. DOI |
28 | Gamen, S., Anel, A., Lasierra, P., Alava, M. A., Martinez-Lorenzo, M. J., Pineiro, A. and Naval, J. (1997). Doxorubicininduced apoptosis in human T-cell leukemia is mediated by caspase-3 activation in a Fas-independent way. FEBS Lett. 417, 360-364. DOI |
29 | Gerlier, D. and Thomasset, N. (1986). Use of MTT colorimetric assay to measure cell activation. J. Immunol. Methods 94, 57-63. DOI ScienceOn |
30 | Kolomeichuk, S. N., Bene, A., Upreti, M., Dennis, R. A., Lyle, C. S., Rajasekaran, M. & Chambers, T. C. (2008). Induction of apoptosis by vinblastine via c-Jun autoamplification and p53-independent down-regulation of p21WAF1/CIP1. Mol. Pharmacol. 73, 128-136. DOI |
31 | Lagadinou, E. D., Ziros, P. G., Tsopra, O. A., Dimas, K., Kokkinou, D., Thanopoulou, E., Karakantza, M., Pantazis, P., Spyridonidis, A. and Zoumbos, N. C. (2008). c-Jun N-terminal kinase activation failure is a new mechanism of anthracycline resistance in acute myeloid leukemia. Leukemia 22, 1899-1908. DOI |
32 | Liu, J. and Lin, A. (2005). Role of JNK activation in apoptosis: a double-edged sword. Cell Res. 15, 36-42. DOI |
33 | Lavrik, I. N., Golks, A. and Krammer, P. H. (2005). Caspases: pharmacological manipulation of cell death. J. Clin. Invest. 115, 2665-2672. DOI |
34 | Lin, A. and Dibling, B. (2002). The true face of JNK activation in apoptosis. Aging Cell 1, 112-116. DOI ScienceOn |
35 | Nishina, H., Wada, T. and Katada, T. (2004). Physiological roles of SAPK/JNK signaling pathway. J. Biochem. 136, 123-126. DOI |
36 | Osborn, M.T. and Chambers, T.C. (1996). Role of the stressactivated/c-Jun NH2-terminal protein kinase pathway in the cellular response to adriamycin and other chemotherapeutic drugs. J. Biol. Chem. 271, 30950-30955. DOI |