Characterization of Plasma Carnitine Level in Obese Adolescent Korean Women
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Yoo, Hye-Hyun
(Bioanalysis & Biotransformation Research Center, Korea Institute of Science and Technology)
Yoon, Ho-Joo (Department of Internal Medicine, College of Medicine, Hanyang University) Shin, Hye-Jung (Department of Health Promotion Center, National Medical Center) Lee, Sang-Hyup (Department of Biomedical & Analytical Chemistry, College of Pharmacy, Duksung Women's University) Yoon, Hye-Ran (Department of Biomedical & Analytical Chemistry, College of Pharmacy, Duksung Women's University) |
1 | Bonnefont, J. P., Demaugre, F., Prip-Buus, C., Saudubray, J. M., Brivet, M., Abadi, N. and Thuillier, L. (1999). Carnitine palmitoyltransferase deficiencies. Mol. Genet. Metab. 68, 424-440 DOI ScienceOn |
2 | Broekhuysen, J., Baudine, A. and Deltour, G. (1965). Effect of carnitine on acidosis and ketosis induced by lipid perfusions in dogs during starvation. Biochim. Biophys. Acta 106, 207-210 DOI ScienceOn |
3 | Ibrahim, W. H., Bailey, N., Sunvold, G. D. and Bruckner, G. G. (2003). Effects of carnitine and taurin on fatty acid metabolism and lipid accumulation in the liver of cats during weight gain and weight loss. Am. J. Vet. Res. 64, 1265-1277 DOI ScienceOn |
4 | Longo, N., Amat di San Filippo, C. and Pasquali, M. (2006). Disorders of carnitine transport and the carnitine cycle. Am. J. Med. Genet. C Semin. Med. Genet. 142C, 77-85 DOI ScienceOn |
5 | McGarry, J. D. and Brown, N. F. (1997). The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis. Eur. J. Biochem. 244, 1-14 DOI ScienceOn |
6 | Minkler, P. E., Kerner, J., North, K. N. and Hoppel, C. L. (2005). Quantitation of long-chain acylcarnitines by HPLC/fluorescence detection: application to plasma and tissue specimens from patients with carnitine palmitoyltransferase-II deficiency. Clin. Chim. Acta 352, 81-92 DOI ScienceOn |
7 | Quiros-Tejeira, R. E., Rivera, C. A., Ziba, T. T., Mehta, N., Smith, C. W. and Butte, N. F. (2007). Risk for nonalcoholic fatty liver disease in Hispanic youth with BMI $>$or =95th percentile. J. Pediatr. Gastroenterol Nutr. 44, 228-236 DOI ScienceOn |
8 | Wutzke, K. D. and Lorenz, H. (2004). The effect of l-carnitine on fat oxidation, protein turnover, and body composition in slightly overweight subjects. Metabolism 53, 1002-1006 DOI ScienceOn |
9 | Stevens, R. D., Hillman, S. L., Worthy, S., Sanders, D. and Millington, D. S. (2000). Assay for Free and Total Carnitine in Human Plasma Using Tandem Mass Spectrometry. Clin. Chem. 46, 727-729 |
10 | Thuillier, L., Rostane, H., Droin, V., Demaugre, F., Brivet, M., Kadhom, N., Prip-Buus, C., Gobin, S., Saudubray, J. M. and Bonnefont, J. P. (2003). Correlation between genotype, metabolic data, and clinical presentation in carnitine palmitoyltransferase 2 (CPT 2) deficiency. Hum. Mutat. 21, 493-501 DOI ScienceOn |
11 | Yang, J. Y., Lee, S. J., Park, H. W. and Cha, Y. S. (2006). Effect of genistein with carnitine administration on lipid parameters and obesity in C57Bl/6J mice fed a high-fat diet. J. Med. Food 9, 459-467 DOI ScienceOn |
12 | Costa, C. G., Dorland, L., de Almeida, I. T., Jakobs, C., Duran, M. and Poll-The, B. T. (1998). The effect of fasting, long-chain triglyceride load and carnitine load on plasma long-chain acylcarnitine levels in mitochondrial very long-chain acyl-CoA dehydrogenase deficiency. J. Inherit. Metab. Dis. 21, 391-399 DOI ScienceOn |
13 | Foster, D. W. (2004). The role of the carnitine system in human metabolism. Ann. N. Y. Acad. Sci. 1033, 1-16 DOI ScienceOn |
14 | Hong, Y. M., Kim, H. S. and Yoon, H. R. (2002). Serum lipid and fatty acid profiles in adriamycin-treated rats after administration of L-carnitine. Pediatr. Res. 51, 249-255 DOI ScienceOn |
15 | Castro-Chavez, F., Yechoor, V. K., Saha, P. K., Martinez-Botas, J., Wooten, E. C., Sharma, S., O'Connell, P., Taegtmeyer, H. and Chan, L. (2003). Coordinated up regulation of oxidative pathways and down regulation of lipid biosynthesis underlie obesity resistance in perilipin knockout mice: a microarray gene expression profile. Diabetes 52, 2666-2674 DOI ScienceOn |
16 | Ronnett, G. V., Kim, E. K., Landree, L. E. and Tu, Y. (2005). Fatty acid metabolism as a target for obesity treatment. Physiol. Behav. 85, 25-35 DOI ScienceOn |
17 | Saper, R. B., Eisenberg, D. M. and Phillips, R. S. (2004). Common dietary supplements for weight loss. Am. Fam. Physician 70, 1731-1738 |
18 | Spiekerkotter, U., Schwahn, B., Korall, H., Trefz, F. K., Andresen, B. S. and Wendel, U. (2000). Very-long-chain acyl-coenzyme A dehydrogenase (VLCAD) deficiency: monitoring of treatment by carnitine/acylcarnitine analysis in blood spots. Acta Paediatr. 89, 492-495 DOI |
19 | Stanley, C. A., Sunaryo, F., Hale, D. E., Bonnefont, J. P., Demaugre, F. and Saudubray, J. M. (1992). Elevated plasma carnitine in the hepatic form of carnitine palmitoyltransferase-1 deficiency. J. Inherit. Metab. Dis. 15, 785-789 DOI |
20 | Yoon, H. R., Hong, Y. M., Boriack, R. L. and Bennett, M. J. (2003). Effect of L-carnitine supplementation on carnitine palmitoyltransferase activates and plasma carnitine concentrations in adriamycin treated rat. Pediatric. Res. 53, 788-792 DOI ScienceOn |
21 | Kuhajda, F. P. and Ronnett, G. V. (2007). Modulation of carnitine palmitoyltransferase-1 for the treatment of obesity. Curr. Opin. Investig. Drugs 8, 312-317 |
22 | Bonnefont, J. P., Djouadi, F., Prip-Buus, C., Gobin, S., Munnich, A. and Bastin, J. (2004). Carnitine palmitoyltransferase 1 and 2: biochemical, molecular and medical aspects. Mol. Aspects Med. 25, 495-520 DOI ScienceOn |
23 | Robitaille, J., Houde, A., Lemieux, S., Perusse, L., Gaudet, D. and Vohl, M. C. (2007). Variants within the muscle and liver isoforms of the carnitine palmitoyltransferase I (CPT 1) gene interact with fat intake to modulate indices of obesity in French-Canadians. J. Mol. Med. 85, 129-137 DOI |
24 | Spiekerkoetter, U., Tokunaga, C., Wendel, U., Mayatepek, E., Exil, V., Duran, M., Wijburg, F. A., Wanders, R. J. and Strauss, A. W. (2004). Changes in blood carnitine and acylcarnitine profiles of very long-chain acyl-CoA dehydrogenase-deficient mice subjected to stress. Eur. J. Clin. Invest. 34, 191-196 DOI ScienceOn |
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