Prunus Yedoensis Inhibits the Inflammatory Chemokines, MDC and TARC, by Regulating the STAT1-Signaling Pathway in IFN-γ-stimulated HaCaT Human Keratinocytes |
Kang, Gyeoung-Jin
(Department of pharmacology, School of Medicine, Cheju National University)
Lee, Hye-Ja (Department of pharmacology, School of Medicine, Cheju National University) Yoon, Weon-Jong (Department of pharmacology, School of Medicine, Cheju National University) Yang, Eun-Jin (Department of pharmacology, School of Medicine, Cheju National University) Park, Sun-Son (Department of pharmacology, School of Medicine, Cheju National University) Kang, Hee-Kyoung (Department of pharmacology, School of Medicine, Cheju National University) Park, Myung-Hwan (GyeongGi Bio-Center) Yoo, Eun-Sook (Department of pharmacology, School of Medicine, Cheju National University) |
1 | Kakinuma, T., Nakamura, K., Wakugawa, M., Mitsui, H., Tada, Y., Saeki, H., Torii, H., Komine, M., Asahina, A. and Tamaki, K. (2002). Serum macrophage-derived chemokine (MDC) levels are closely related with the disease activity of atopic dermatitis. Clin. Exp. Immunol. 127, 270-273 DOI |
2 | Komine, M. and Kakinuma, T., Kagami, S., Hanakawa, Y., Hashimoto, K., Tamaki, K. (2005). Mechanism of thymus- and activation-regulated chemokine(TARC)/CCL17 production and its modulation by roxithromycin. J. Invest. Dermatol. 125, 491-498 DOI ScienceOn |
3 | Luster, A. D. (2001). Antichemokine immunotherapy for allergic diseases. Allergy Clin. Immunol. 1, 561-567 |
4 | Noshita, T., Sakaguchi, A., and Funayama, S. (2006). Isolation of ethyl caffeate from the petals of Prunus yedoensis J. Nat. Med. 60, 266-267 DOI |
5 | Vestergaard, C., Yoneyama, H., Murai, M., Nakamura, K., Tamaki, K., Terashima, Y., Imai, T., Yoshie, O., Irimura, T., Mizutani, H. and Matsushima, K. (1999). Overproduction of Th2-specific chemokines in NC/Nga mice exhibiting atopic dermatitis-like lesions. J. Clin. Clin. Exp. Allergy 104, 1097-1105 DOI ScienceOn |
6 | Wormald, S., Hilton, D. J., Smyth, G. K. and Speed, T. P. (2006). Proximal genomic localization of STAT1 binding and regulated transcriptional activity. BMC Genomics. 7, 254 DOI |
7 | Xiao, T., Kagami, S., Saeki, H., Sugaya, M., Kakinuma, T., Fujita, H., Yano, S., Mitsui, H., Torii, H., Komine, M., Asahina, A., Nakamura, K. and Tamaki, K. (2003). Both IL-4 and IL-13 inhibit the TNF-α and IFN-γ enhanced MDC production in a human keratinocyte cell line, HaCaT cells. J. Dermatol. Sci. 31, 111-117 DOI ScienceOn |
8 | Bordignon, V, Sinagra J. L., Trento E., Pietravalle M., Capitanio, B. and Fei, P. C. (2005). Antigen specific cytokine response in pediatric patients with atopic dermatitis. Pediatr Allergy Immunol. 16,113-120 DOI ScienceOn |
9 | Baumer, W., Seegers, U., Braun, M., Tschernig, T. and Kietzmann, M. (2004). TARC and RANTES, but not CTACK, are induced in two models of allergic contact dermatitis. Effects of cilomilast and diflorasone diacetate on T-cell-attracting chemokines. Br. J. Dermatol. 151, 823-830 DOI ScienceOn |
10 | Bonncchi, R., Sozzani, S., Stine, J. T., Luini, W., D'Amico, G., Allavena, P., Chantry, D. and Mautovani. A. (1998). Divergent effects of Interleukin-4 and Interferon- on Macrophage-Derived Chemokine production : An amplification circuit of polarized T helper 2 responses. Blood 92, 2668-2671 |
11 | Hijnen, D., De Bruin-Weller, M., Oosting, B., Lebre C., De Jong, E., Bruijnzeel-Koomen, C. and Knol, E. (2004). Serum thymus and activation-regulated chemokine (TARC) and cutaneous T cell-attracting chemokine (CTACK) levels in allergic diseases: TARC and CTACK are disease-specific markers for atopic dermatitis. J. Allergy Clin. Immunol. 113, 334-40 DOI ScienceOn |
12 | Chiang, Y. M, Lo, C. P., Chen, Y. P., Wang, S. Y., Yang, N. S., Kuo, Y. H., and Shyur, L. F. (2005). Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin. Br .J. Pharmacol. 146, 352-63 DOI ScienceOn |
13 | Esche, C., de Benedetto, A. and Beck, L. A. (2004). Keratinocytes in atopic dermatitis: Inflammatory signals. Cur. Allergy Asthma Rep. 4, 276-284 DOI |
14 | Godiska, R., Chantry, D., Raport, C. J., Sozzanl, S., Allavena, P., Leviten, D., Mantovani, A. and Gray, P. W. (1997). Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells. J. Exp. Med. 185, 1595-1604 DOI |
15 | Jakubzick, C., Wen, H., Matsukawa, A., Keller, M., Kunkel, S. L. and Hogaboam, C. M. (2004). Role of CCL4 ligands, CCL17 and CCL22, during schistosoma mansoni egg-induced pulmonary granuloma formation in mice. Am. J. Pathol. 165, 1211-1221 DOI ScienceOn |
16 | Kanda, N. and Watanabe, S. (2007). Prolactin enhances interferon-g-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes. Endocrinol. 148, 2317-2325 DOI ScienceOn |
17 | Nakazato, J., Kishida, M., Kuroiwa, R., Fujiwara, J., Shimoda, M., and Shinomiya, N. (2008). Serum levels of Th2 chemokines, CCL17, CCl22, and CCl27, were the important markers of severity in infantile atopic dermatitis. Pediatr. Allergy Immunol. 1, 10 DOI ScienceOn |
18 | Saeki, H. and Tamaki, K. (2006). Thymus and activation regulated chemokine(TARC)/CCL17 and skin diseases. J. Dermatol. Clin. Exp. Allergy 43, 75-84 DOI ScienceOn |
19 | Horikawa, T., Nakayama, T., Hikita, I., Yamada, H., Fujisawa, R., Bito, T., Harada, S., Fukunaga, A., Chantry, D., Gray, P. W., Morita, A., Suzuki, R., Tezuka, T., Ichihashi, M. and Yoshie, O. (2002). IFN--inducible expression of thymus and activation-regulated chemokine/CCL17 and macrophage-derived chemokine/CCL22 in epidermal keratinocytes and their roles in atopic dermatitis. Int. Immunol. 7, 767-773 |
20 | Ivashkiv, L. B. and Hu, X. (2004). Signaling by STATs. Arthritis Res. Ther. 6, 159-168 DOI ScienceOn |
21 | Best, S. M., Morris, K. L., Shannon, J. G., Robertson, S. J., Mitzel, D. N., Park, G. S., Boer, E., Wolfinbarger, J. B. and Bloom, M. E. (2005). Inhibition of interferon-stimulated JAKSTAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist. J. Virol. 76,12828-12839 DOI ScienceOn |
22 | Bito, T., Roy, S., Sen, C. K., Shirakawa, T., Gotoh, A., Ueda, M., Ichihashi, M. and Packer, L. (2002). Flavonoids differentially regulate IFN gamma-induced ICAM-1 expression in human keratinocytes: molecular mechanisms of action. FEBS Lett. 520, 145-52 DOI ScienceOn |
23 | Park, E. S., Shin, M. K. and Song, H. J. (1998). A study on the antiallergic effect of cortex betula platyphyllae or cortex pruni serrulatae extract. Kor. J. Herbology. 13, 57-69 |
24 | Portengen, L., Sigsgaard, T., Omland, O, Hjort, C., Heederik, D., and Doekes, G. (2002). Low prevalence of atopy in young Danish farmers and farming students born and raised on a farm. Clin. Exp. Allergy. 32, 247-253 DOI |
25 | Hamalainen, M., Nieminen, R., Vuorela, P., Heinonen, M., and Moilanen, E. (2007). Anti-inflammatory effects of flavonoids: genistein, kaempferol, quercetin, and daidzein inhibit STAT-1 and NF-kappaB activations, whereas flavone, isorhamnetin, naringenin, and pelargonidin inhibit only NF-kappaB activation along with their inhibitory effect on iNOS expression and NO production in activated macrophages. Mediators Inflamm. 2007, 45673 |
26 | Fujisawa, T., Fujisawa, R., Kato, Y., Nakayama, T., Morita, A., Katsumata, H., Nishimori, H., Iguchi, K., kamiya, H., Gray, P. W., Chantry, D., Suzuki, R. and Yoshie, O. (2002). Presence of high contents of thymus and activation-regulated chemokine in platelets and elevated plasma levels of thymus and activation-regulated chemokine and macrophage-derived chemokine in patients with atopic dermatitis. J. Allergy Clin. Immunol. 110, 139-146 DOI ScienceOn |
27 | Strobl, B., Arulampalam, V., Is'harc, H., Newman, S. J., Schlaak, J. F., Watling, D., Costa-Pereira, A. P., Schaper, F., Behrman, I., Sheehan, K. C. F., Schreiber, R. D., Horn, F., Heinrich, P.C. and Kerr, I. M. (2001). A completely foreign receptor can mediate an interferon--like response. EMBO J. 20, 5431-5442 DOI |
28 | Rozyk, K. J., Targowski, T., Paluchowska, E., Owczarek, W. and Kucharczyk, A. (2005). Serum thymus and activation-regulated chemokine, Macrophage-derived chemokine and eotaxin as marker of severity of atopic dermatitis. Allergy 60, 685-688 DOI ScienceOn |
29 | Shimada, Y., Takehara, K. and Sato, S. (2004). Both Th2 and Th1 chemokines (TARC/CCL17, MDC/CCL22, and Mig/CXCL9) are elevated in sera from patients with atopic dermatitis. J. Dermatol. Clin. Exp. Allergy 24, 201-208 DOI ScienceOn |
30 | Grewe, M., Gyufko, K., Schopf, E. and Krutmann, J. (1994). Expression of interferon-gamma in atopic eczema. Lancet 343, 25-26 DOI ScienceOn |
31 | Han, B. H. and Han, Y. N. (1978). Immunosuppressant activity of cheery bark extract. Kor. J. Pharmacog. 9, 173-175 |
32 | Han, S. K., Song, J. Y., Yun, Y. S. and Yi, S. Y. (2002). Gamma irradiation-reduced expression, STAT1 signals, and cellmediated immunity. J. Biochem. Mol. Biol. 35, 583-589 DOI ScienceOn |
33 | Yu, B., Koga, T., Urabe, K., Moroi, Y., Maeda, S., Yanagihara, Y. and Furue, M. (2002). Differential regulation of thymus- and activation-regulated chemokine induced by IL-4, IL-13, TNFalpha and IFN-gamma in human keratinocyte and fibroblast. J. Dermatol. Sci. 30, 29-36 DOI ScienceOn |