Pharmacokinetic Study of Promethazine in Korean Healthy Subjects Using a Validated HPLC Method |
Jang, Jung-Ok
(College of Pharmacy, Ewha Womans University)
Go, Eun-Jung (College of Pharmacy, Ewha Womans University) Kim, Na-Hyung (College of Pharmacy, Ewha Womans University) Chung, Soo-Yeon (College of Pharmacy, Ewha Womans University) Park, Hyo-Min (College of Pharmacy, Ewha Womans University) Lee, Hwa-Jeong (College of Pharmacy, Ewha Womans University) |
1 | DiGregorio G. J. and Ruch E. (1980) Human whole blood and parotid saliva concentrations of oral and intramuscular promethazine. J Pharm. Sci. 69, 1457-1459 DOI |
2 | Fox, A.R. and McLoughlin D. A. (1993) Rapid, sensitive high-performance liquid chromatographic method for the quantification of promethazine in human serum with electrochemical detection. J Chromatogr. 631, 255-259 DOI ScienceOn |
3 | Vanapalli, S. R., Kambhampati, S. P., Putcha, L. and Bourne, D. W. A. (2001). A liquid chromatographic method for the simultaneous determination of promethazine and three of its metabolites in plasma using electrochemical and UV detectors. J Chromatogr. Sci., 39, 70-72 DOI ScienceOn |
4 | Wallace, J. E., Shimek, E. Jr., Stavchansky, S. and Harris, S. C. (1981). Determination of promethazine and other phenothiazine compounds by liquid chromatography with electrochemical detection. Anal. Chem. 53, 960-962 DOI ScienceOn |
5 | Stavchansky, S., Wallace, J. E., Geary, R., Hecht, G.., Robb, C. A. and Wu, P. (1987). Bioequivalence and phannacokinetic profile of promethazine hydrochloride suppositories in humans. J Pharm. Sci. 76, 441-445 DOI |
6 | Lackner, J. R. and Graybiel, A. (1994). Use of promethazine to hasten adaptation to provocative motion. J Clin. Pharmacal. 34, 644-648 DOI ScienceOn |
7 | Pistos, C. and Stewart, J. T. (2003). Direct injection HPLC method for the determination of selected phenothiazines in plasma using a Hisep column. Biomed. Chromatogr. 17, 465-470 DOI ScienceOn |
8 | Quinn J. and Calvert R. (1976). The disposition of promethazine in man [proceedings]. J Pharm. Pharmacol. 28, suppl-59 |
9 | Schwinghammer, T. L., Juhl, R. P., Dittert, L. W., Melethil, S. K., Kroboth, F. J. and Chung, V.S. (1984). Comparison of the bioavailability of oral, rectal and intramuscular promethazine. Biopharm. Drug Dispos. 5, 185-194 DOI ScienceOn |
10 | Song, Q. and Putcha, L. (2001) Quantitation of promethazine and metabolites in urine samples using on-line solid-phase extraction and column-switching. J Chromatogr. B. 763, 920 |
11 | Strenkoski-Nix, L.C., Ermer, J., DeCleene, S., Cevallos, W. and Mayer, P.R. (2000). Pharmacokinetics of promethazine hydrochloride after administration of rectal suppositories and oral syrup to healthy subjects. Am. J Health-Syst. Pharm. 57, 1499-1505 |
12 | Taylor, G.., Houston, J. B., Shaffer J. and Mawer, G. (1983). Pharmacokinetics of promethazine and its sulphoxide metabolite after intravenous and oral administration to man. Br. J Clin. Pharmacol. 15, 287-293 DOI ScienceOn |
13 | Temdrup, T. E., Dire, D. J., Madden. C. M., Davis, H., Cantor, R. M. and Gavula, D. P. (1991). A prospective analysis of intramuscular meperidine, promethazine, and chlorpromazine in pediatric emergency department patients. Ann. Emerg. Med. 20, 31-35 DOI ScienceOn |
14 | Bagli, M., Rao, M. L., Hoflich, G. (1994) Quantification of chlorprothixene, levomepromazine and promethazine in human serum using high-performance liquid chromatography with coulometric electrochemical detection. J Chromatogr. B Biomed. Appl. 657, 141-148 DOI ScienceOn |
15 | Zaman, R., Honigberg, I. L., Francisco, G. E., Kotzan J. A., Stewart, J. T., Brown W. J., Shah. V. P. and Pelsor, F. R. (1986). Bioequivalency and dose proportionality of three tableted promethazine products. Biopharm. Drug Dispos. 7, 281-291 DOI ScienceOn |
16 | Tarkkila, P., Tom, K., Tuominen, M. and Lindgren, L. (1995). Premedication with promethazine and transdermal scopolamine reduces the incidence of nausea and vomiting after intrathecal morphine. Acta Anaesthesiol. Scand. 39, 983-986 DOI ScienceOn |