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http://dx.doi.org/10.14402/jkamprs.2013.35.2.107

Differential Diagnosis of Oral Lesions for the Initial Diagnosis of Acute Lymphoblastic Leukemia  

Seo, Mi Hyun (Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University)
Ha, Ji Young (Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University)
Huh, Kyung Hoe (Department of Oral and Maxillofacial Radiology, School of Dentistry, Seoul National University)
Cho, Young Ah (Department of Oral Pathology, School of Dentistry, Seoul National University)
Kim, Soung Min (Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University)
Choi, Jin Young (Department of Oral and Maxillofacial Surgery, School of Dentistry, Seoul National University)
Publication Information
Maxillofacial Plastic and Reconstructive Surgery / v.35, no.2, 2013 , pp. 107-111 More about this Journal
Abstract
Careful examination of the oral cavity may reveal findings indicative of an underlying systemic condition, and allow for early diagnosis and treatment. Examination should include evaluation for mucosal changes, periodontal inflammation and bleeding, and general condition of the teeth. A 12-year-old man visited for molar pain during 3 months. He was diagnosed with having a possibility of hematopoietic malignancy, showing the loss of lamina dura, destruction of bony crypt, and high attenuation in the bone marrow. He was referred to department of pediatrics, additional study, including peripheral cell morphology and bone marrow exam, were performed, and diagnosed as acute lymphoblastic anemia. Despite chemotherapy to cure leukemia, he was expired 8 months after initial diagnosis. The purpose of this report is to promote and evoke the awareness regarding an initial examination of the dentist to make an effort to acquire accurate knowledge and information about life-threatening disease in usual dental practice.
Keywords
Acute leukemia; Dentists; Early diagnosis; Life-threatening disease;
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