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The Effect of ER:YAG Laser & ER,CR:YSGG Laser on the Tissue of the Inflammation-Induced Mouse  

Park, Tae-Il (Hallym University)
Lee, Hyung-Seok (Hallym University)
Lee, Hee-Jong (Hallym University)
Chae, Chang-Hoon (Graduate school of clinical dentistry, Hallym University)
Lee, Young-Joo (Department of Oral & Maxillofacial Surgery, Kang-dong Sacred Heart Hospital, College of Medicine, Hallym University)
Byeon, Kwang-Seob (Department of Oral & Maxillofacial Surgery, Kang-dong Sacred Heart Hospital, College of Medicine, Hallym University)
Hong, Soon-Min (Department of Oral & Maxillofacial Surgery, Kang-dong Sacred Heart Hospital, College of Medicine, Hallym University)
Choi, Mee-Ra (Department of Prosthodontics, Kang-dong Sacred Heart Hospital, College of Medicine, Hallym University)
Park, Jun-Woo (Department of Oral & Maxillofacial Surgery, Kang-dong Sacred Heart Hospital, College of Medicine, Hallym University)
Publication Information
Maxillofacial Plastic and Reconstructive Surgery / v.32, no.5, 2010 , pp. 396-405 More about this Journal
Abstract
Purpose: This study was performed to find out the effects of the Er:YAG laser (Key Laser) & Er,Cr:YSGG laser (Water Laser) on inflammatory tissues. Materials and Methods: It was performed on about 20 g, 6 weeks male ICR mouses. They were grouped into the control (negative), the inflammation induced 'control'(positive), Er,Cr:YSGG laser exposured group after inducing inflammation, Er:YAG lasere exposured group after inducing inflammation each 15 mouses. The mouses were applicated 0.5% DNFB 1 cc on ear skin twice a day for 4 days until symptom expression. After laser exposure, ear tissues were extracted and defined gene expression by RT-PCR. Then, tissue staining, lymphocytes observation, electromicroscophic laboratory were carried out. Results: Interleukin-$1{\beta}$ was expressed much less in the A-laser exposed group. Interleukin-$1{\beta}$ & Tumor Necrosis Factor-${\alpha}$ were expressed 7 times lesser in the A-laser exposed group. The number of Lymphocytes related to inflammation was decreased rapidly in the A-laser exposed group in vivo. he number of cavity recovered normal was a little bigger in the A-laser exposed group after 5 days Conclusion: The expression of IL-$1{\beta}$ & TNF-${\alpha}$, hitologic change, observation with electron microscope shows that Erbium laser exposure causes lesser inflammation with A-laser rather than B-laser.
Keywords
Laser therapy; IL-$1{\beta}$ & TNF-${\alpha}$; Mice; Electron microscope;
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