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CASE REPORT OF MULTIPLE ODONTOGENIC KERATOCYSTS WITH BASAL CELL NEVUS SYNDROME  

Park, Ji-Hyun (Department of Oral and Maxillofacial Surgery, College of Medicine, Inje University Sanggye Paik Hospital)
Yoon, Kyu-Ho (Department of Oral and Maxillofacial Surgery, College of Medicine, Inje University Sanggye Paik Hospital)
Park, Kwan-Soo (Department of Oral and Maxillofacial Surgery, College of Medicine, Inje University Sanggye Paik Hospital)
Cheong, Jeong-Kwon (Department of Oral and Maxillofacial Surgery, College of Medicine, Inje University Sanggye Paik Hospital)
Shin, Jae-Myung (Department of Oral and Maxillofacial Surgery, College of Medicine, Inje University Sanggye Paik Hospital)
Choi, Mun-Kyung (Department of Oral and Maxillofacial Surgery, College of Medicine, Inje University Sanggye Paik Hospital)
Publication Information
Maxillofacial Plastic and Reconstructive Surgery / v.30, no.2, 2008 , pp. 172-177 More about this Journal
Abstract
Basal cell nevus syndrome, also known as Gorlin-Goltz syndrome, is a hereditary condition transmitted as an autosomal dominant trait that exhibits high penetrance and variable expressivity. It is an ecto-mesodermal polydysplasia with numerous manifestations that affect multiple organs. Odontogenic keratocysts, palmar and plantar pits, and hypertelorism are the most frequently observed anomalies. Currently there are new lines of investigation based on biomolecular studies, which aim at identifying the molecules responsible for these cysts and thus early allowing an early diagnosis of these patients. We report two cases of multiple odontogenic keratocysts associated with basal cell nevus syndrome.
Keywords
Odontogenic keratocyst; Basal cell nevus syndrome;
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1 Gorlin RJ, and Goltz RW : Multiple nevoid basal-cell epithelioma, Jaw cysts and bifid rib. N eng J Med 262 : 908, 1960   DOI   ScienceOn
2 Lo Muzio L, Nocini P, Bucci P et al : Early diagnosis of nevoid basal cell carcinoma syndrome. J Am Dent Assoc 130 : 669, 1999   DOI
3 Woolgar JA, Rippini JW, Browne RM : A comparative histological study of odontogenic keratocyst in basal cell nevus syndrome and control patients. J Oral Pathol 16 : 75, 1987   DOI
4 Addessi G, Del Vecchio A, Maggiore C et al : Gorlin's syndrome. Case report. Minerva Stomatol 51 : 145, 2002   PUBMED
5 Totten JR : The multiple nevoid basal cell carcinoma syndrome. Report of its occurrence in four generations of a family. Cancer 46 : 1456, 1980   DOI   ScienceOn
6 Bale AE : The nevoid basal cell carcinoma syndrome: genetics and mechanism of carcinogenesis. Cancer Invest 15 : 180, 1997   DOI   ScienceOn
7 Hogan RE, Tress B, Gonzales MF et al : Epilepsy in the nevoid basal- cell carcinoma syndrome (Gorlin syndrome): report of a case due to a focal neuronal heterotopia. Neurology 46 : 574, 1996   DOI   PUBMED
8 Kimonis VE, Goldstein AM, Pastakia B et al : Clinical manifestations in 105 persons with nevoid basal cell carcinoma syndrome. Am J Med Genet 69 : 299, 1997   DOI   ScienceOn
9 Schoenberg BS : Multiple primary neoplasm and nervous system. Cancer 40 : 1961, 1977   DOI   ScienceOn
10 Howell JB, Anderson DE : "The basal-cell nevus"by Howell and Caro, January 1959. Commentary: The nevoid basal cell carcinoma syndrome. Arch Dermatol 188 : 824, 1982
11 Johnson RL, Rothman AL, Xie J et al : Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 272 : 1668, 1996   DOI   ScienceOn
12 Gailani MR, Bale SJ, Leffell DJ et al : Development defects in Gorlin syndrome related a putative tumor suppressor gene on chromosome 9. Cell 69 : 111, 1992   DOI   ScienceOn
13 Pogrel MA, Smichdt BL, eds. Oral and maxillofacial surgery clinics of North America. Philadelphia: WBS Saunders Company, 2003, p.383
14 O'Malley S, Weitman D, Olding M et al : Multiple neoplasms following craniospinal irradiation for medulloblastoma in a patient with nevoid basal cell carcinoma syndrome. Case report. Journal of Neurosurgery 86 : 286, 1997   DOI   ScienceOn
15 Shafer, Hine, Levy : A Textbook of Oral Pathology, 4th ed. Saunders, 1983 p.273
16 Zerin JM, Ainge G : Facial deformity and rash. Investigative Radiology 24 : 159, 1989   DOI
17 Gorlin RJ : Nevoid basal cell carcinoma (Gorlin) syndrome: unanswered issues. J Lab Clin Med 134 : 551, 1999.   DOI   ScienceOn
18 Johnson RL, Rothman AL, Xie J et al : Human homolog of patched, a candidate gene for the basal cell nevus syndrome Science 272 : 1668, 1996   DOI   ScienceOn
19 Evans DG, Ladusans EJ, Rimmer S et al : Complications of the naevoid basal cell carcinoma syndrome: results of a population based study. J Med Genet 30 : 460, 1993   DOI
20 Reisner KR, Riva RD, Cobb RJ et al : Treating nevoid basal cell carcinoma syndrome. J Am Den Assoc 125 : 1007, 1994   DOI
21 Wicking C, Bale AE : Molecular basis of the nevoid basal cell carcinoma syndrome. Current Opinion in Pediatrics 9 : 630, 1997   DOI   PUBMED   ScienceOn
22 Zedan W, Robinson PA, Markham AF et al : Expression of the Sonic Hedgehog receptor "PATHCED"in Basal cell carcinomas and odontogenic keratocysts. J Pathol 194 : 473, 2001   DOI   ScienceOn
23 Soekarman D, Fryns JP, Casaer P et al : Increased head circumference and facial cleft as presenting signs of the nevoid basal-cell carcinoma syndrome. Genetic Counseling 2 : 153, 1991