Browse > Article

A CLINICAL STUDY OF METASTATIC CARCINOMA TO ORAL SOFT TISSUE  

Park, Joo-Yong (Oral Cancer Clinic, Research Institute and Hospital, National Cancer Center)
Kim, Hyung-Sup (Oral Cancer Clinic, Research Institute and Hospital, National Cancer Center)
Ok, Yong-Ju (Dept. of Oral &Maxillofacial Surgery, College of Dentistry, Seoul National University)
Song, Jin-A (Dept. of Oral &Maxillofacial Surgery, College of Dentistry, Seoul National University)
Lee, Jong-Ho (Dept. of Oral &Maxillofacial Surgery, College of Dentistry, Seoul National University)
Kim, Myung-Jin (Dept. of Oral &Maxillofacial Surgery, College of Dentistry, Seoul National University)
Choi, Sung-Weon (Oral Cancer Clinic, Research Institute and Hospital, National Cancer Center)
Publication Information
Maxillofacial Plastic and Reconstructive Surgery / v.27, no.4, 2005 , pp. 346-349 More about this Journal
Abstract
Metastatic tumours to oral soft tissue are uncommon and accounts for approximately 1% of malignant oral neoplasms. Because of its rarity and clinical appearance of benign nature, the diagnosis of a metastatic lesion in the oral soft tissue may be challenging, both to clinicians and pathologists. We analyzed the clinical data of 9 patients who had metastatic carcinoma to oral soft tissues. The metastatic site to oral soft tissue was the gingiva in all cases. The most common primary site was lung (6 cases) followed by liver (2 cases) and breast (1 case). The clinical appearance resembled gingiva hyperplasia, pyogenic granuloma or gingival swelling. In one case, the metastatic gingiva lesion was found before detection of primary cancer. The mean survival time after diagnosis of metastatic lesion was 3 months. Although this metastatic lesion is rare, oral and maxillofacial surgeon should recognized that benign inflammatory lesion may be the metastatic malignant lesion or the first sign of undiagnosed underlying malignancy.
Keywords
Metastatic tumour; Gingiva;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Chin A, Liang TS, Borislow AJ : Initial presentation of hepatocellular carcinoma as a mandibular mass: case report and review of the literature. Oral Surg Oral Med Oral Pathol 86 : 457, 1998   DOI   ScienceOn
2 Hirshberg A, Leibovich P, Buchner A : Metastatic tumors to the jaws: analysis of 390 cases. J Oral Pathol Med 22 : 337, 1993   DOI   ScienceOn
3 Ellis GL, Jensen JL, Reingold IM : Malignant neoplasms metastatic to gingiva. J Oral Surg 44 : 238, 1977   DOI   ScienceOn
4 Shankar S : Dental pulp metastases and pan-osseous mandibular involvement with mammary adenocarcinoma. Br J Oral Maxillofac Surg 22(6) : 455, 1984   DOI   ScienceOn
5 Kim RY, Perry SR, Levy DS : Metastatic carcinoma to the tongue: a report of two cases and a review of the literature. Cancer 43(1) : 386, 1979   DOI   PUBMED   ScienceOn
6 Nagy JA, Brown LF, Senger DR : Pathogenesis of tumour stroma generation: acritical role for leaky blood vessels anda fibrin deposition. Biochem Biophysis Acta 948 : 305, 1989
7 Hirshberg A, Buchhner A : Metastatic tumors to the oral regions. An overview. Eurpopean J Cancer B Oral Oncol 31B : 355, 1995
8 Raveglia F, Meda Stefano et al : Personal experience in surgical management of pulmonary pleomorphic carcinoma. 78 : 1742, 2004   DOI   ScienceOn
9 Hirshberg A, Leibovich P, Buchner A : Metastases to the oral mucosa: Analysis of 157 cases. J Oral Pathol Med 22 : 385, 1993   DOI   ScienceOn
10 Myers I, Shklar G : Malignant tumors metastatic to mouth and jaws. Oral Surgery 20 : 350, 1965   DOI   ScienceOn
11 Hashimoto N, Kurihara K, Yamasaki H, Ohba S, Sakai H, Yoshida S : Pathological characteristics of metastatic carcinoma in the human mandible. J Oral Pathol 16(7) : 362, 1987   DOI   PUBMED
12 O Carroll MK, Krolls SO, Mosca NG : Metastatic carcinoma to the mandible. Report of two cases. Oral Surg Oral Med Oral Pathol 76(3) : 368, 1993   DOI   ScienceOn