THE EFFECT OF RHBMP-2 IN HUMAN BONE MARROW-DERIVED STEM CELLS AS OSTEOGENIC INDUCERS |
Kim, In-Sook
(Dental Research Institute, Seoul National University)
Zhang, Yu-Lian (Dental Research Institute, Seoul National University) Cho, Tae-Hyung (Dental Research Institute, Seoul National University) Lee, Kyu-Back (Dept. of Biomedical Engineering, College of Medicine, Brain Korea 21 Program for Biomedical Science, Korea Artificial Organ Center, Korea University) Park, Yong-Doo (Dept. of Biomedical Engineering, College of Medicine, Brain Korea 21 Program for Biomedical Science, Korea Artificial Organ Center, Korea University) Rho, In-Sub (Chemical Engineering Department, Seoul National University of Technology) Weber, F. (Lab. for Osteology, Dept. of Craniomaxillofacial Surgery, University Hospital Zurich) Hwang, Soon-Jung (Dept. of Oral & Maxillofacial Surgery, College of Dentistry, Seoul National University) Kim, Myung-Jin (Dept. of Oral & Maxillofacial Surgery, College of Dentistry, Seoul National University) Lee, Jong-Ho (Dept. of Oral & Maxillofacial Surgery, College of Dentistry, Seoul National University) |
1 | Balk ML, Bray J, Day C, Epperly M, Greenberger J, et al : Effect of rhBMP-2 on the osteogenic potential of bone marrow stromal cells from an osteogenesis imperfecta mouse (oim). Bone 21(1) : 7, 1997 DOI ScienceOn |
2 | Skillington J, Choy L, Derynck R : Bone morphogenetic protein and retinoic acid signaling cooperate to induce osteoblast differentiation of preadipocytes. J Cell Biol 159(1) : 135, 2002 DOI ScienceOn |
3 | Lee KS, Kim HJ, Li QL, Chi XZ, et al : Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12. Mol Cell Biol 20(23) : 8783, 2000 DOI ScienceOn |
4 | Diefenderfer DL, Osyczka AM, Reilly GC, Leboy PS : BMP responsiveness in human mesenchymal stem cells. Connect Tissue Res 44 Suppl 1:305, 2003 DOI ScienceOn |
5 | Katagiri T, Yamaguchi A, Komaki M, Abe E, et al : Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. J Cell Biol 127(6 Pt 1) : 1755, 1994 DOI ScienceOn |
6 | Owen TA, Aronow M, Shalhoub V, Barone LM, et al : Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix. J Cell Physiol 143(3) : 420, 1990 DOI PUBMED |
7 | Ducy P, Starbuck M, Priemel M, Shen J, et al : A Cbfa1- dependent genetic pathway controls bone formation beyond embryonic development. Genes Dev 13(8) : 1025, 1999 DOI ScienceOn |
8 | Shui C, Spelsberg TC, Riggs BL, Khosla S : Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells. J Bone Miner Res 18(2) : 213, 2003 DOI ScienceOn |
9 | Gori F, Thomas T, Hicok KC, Spelsberg TC, et al : Differentiation of human marrow stromal precursor cells: bone morphogenetic protein-2 increases OSF2/CBFA1, enhances osteoblast commitment, and inhibits late adipocyte maturation. J Bone Miner Res 14(9) : 1522, 1999 DOI ScienceOn |
10 | Dezawa M, Kanno H, Hoshino M, Cho H, Matsumoto N, et al : Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation. J Clin Invest 113(12) : 1701, 2004 DOI PUBMED |
11 | Cheng SL, Zhang SF, Avioli LV: Expression of bone matrix proteins during dexamethasone-induced mineralization of human bone marrow stromal cells. J Cell Biochem 61(2) : 182, 1996 DOI PUBMED |
12 | Rickard DJ, Sullivan TA, Shenker BJ, Leboy PS, Kazhdan I, et al : Induction of rapid osteoblast differentiation in rat bone marrow stromal cell cultures by dexamethasone and BMP-2. Dev Biol 161(1) : 218, 1994 DOI ScienceOn |
13 | Hay E, Hott M, Graulet AM, Lomri A, Marie PJ: Effects of bone morphogenetic protein-2 on human neonatal calvaria cell differentiation. J Cell Biochem 72(1) : 81, 1999 DOI ScienceOn |
14 | Peter SJ, Liang CR, Kim DJ, Widmer MS, Mikos AG : Osteoblastic phenotype of rat marrow stromal cells cultured in the presence of dexamethasone, beta-glycerolphosphate, and L-ascorbic acid. J Cell Biochem 71(1) : 55, 1998 DOI ScienceOn |
15 | Diefenderfer DL, Osyczka AM, Garino JP, Leboy PS : Regulation of BMP-induced transcription in cultured human bone marrow stromal cells. J Bone Joint Surg Am 85-A Suppl 3 : 19, 2003 PUBMED |
16 | Robey PG, Termine JD : Human bone cells in vitro. Calcif Tissue Int 37(5) : 453, 1985 DOI ScienceOn |
17 | Lian JB, et al : Species-specific glucocorticoid and 1,25- dihydroxyvitamin D responsiveness in mouse MC3T3-E1 osteoblasts: dexamethasone inhibits osteoblast differentiation and vitamin D down-regulates osteocalcin gene expression. Endocrinology 138(5) : 2117, 1997 DOI ScienceOn |
18 | Otto F, Thornell AP, Crompton T, Denzel A, et al : Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell 89(5) : 765, 1997 DOI ScienceOn |
19 | Prockop DJ : Marrow stromal cells as stem cells for nonhematopoietic tissues. Science 276(5309) : 71, 1997 DOI ScienceOn |
20 | Rickard DJ, et al : Isolation and Characterization of Osteoblast Precursor Cells from Human Bone Marrow. Journal of Bone & Mineral Research March 11(3) : 312, 1996 DOI ScienceOn |
21 | Si X, Yang L, Y. Jin : [Effects of human BMP2 gene transfection on NIH3T3 cells in vitro]. Zhonghua Kou Qiang Yi Xue Za Zhi 34(2) : 103, 1999. PUBMED |
22 | Osyczka AM, Diefenderfer DL, Bhargave G, Leboy PS : Different effects of BMP-2 on marrow stromal cells from human and rat bone. Cells Tissues Organs 176(1-3) : 109, 2004 DOI ScienceOn |
23 | Muraglia A, Cancedda R, Quarto R : Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model. J Cell Sci 113 : 1161, 2000 PUBMED |
24 | Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, et al : Multilineage potential of adult human mesenchymal stem cells. Science 284(5411) : 143, 1999 DOI PUBMED ScienceOn |
25 | Satokata I, Ma L, Ohshima H, Bei M, et al : Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation. Nat Genet 24(4) : 391, 2000 DOI ScienceOn |
26 | Yamaguchi A, Katagiri T, Ikeda T, Wozney JM, et al : Recombinant human bone morphogenetic protein-2 stimulates osteoblastic maturation and inhibits myogenic differentiation in vitro. J Cell Biol 113(3) : 681, 1991 DOI ScienceOn |
27 | Cheng SL, Mackay AM, Beck SC, Jaiswal RK, et al : Differentiation of human bone marrow osteogenic stromal cells in vitro: induction of the osteoblast phenotype by dexamethasone. Endocrinology 134(1) : 277, 1994 DOI ScienceOn |
28 | Leboy PS, Beresford JN, Devlin C, Owen ME, et al : Dexamethasone induction of osteoblast mRNAs in rat marrow stromal cell cultures. J Cell Physiol 146(3) : 370, 1991 DOI PUBMED |
29 | Vilamitjana-Amedee J, Bareille R, Rouais F, Caplan AI, Harmand MF, et al : Human bone marrow stromal cells express an osteoblastic phenotype in culture. In Vitro Cell Dev Biol Anim 29A(9) : 699, 1993 PUBMED |
30 | Ryoo HM, Hoffmann HM, Beumer T, Frenkel B, et al : Stage-specific expression of Dlx-5 during osteoblast differentiation: involvement in regulation of osteocalcin gene expression. Mol Endocrinol 11(11) : 1681, 1997 DOI ScienceOn |
31 | Nakashima K, Zhou X, Kunkel G, Zhang Z, et al : The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell 108(1) : 17, 2002 DOI ScienceOn |
32 | Lecanda F, Avioli LV, Cheng SL : Regulation of bone matrix protein expression and induction of differentiation of human osteoblasts and human bone marrow stromal cells by bone morphogenetic protein-2. J Cell Biochem 67(3) : 386, 1997 DOI ScienceOn |