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http://dx.doi.org/10.7783/KJMCS.2016.24.3.222

Antioxidant and α-Glucosidase Inhibitory Activities of Tradescantia pallida (Rose) Hunt Leaf Extract and Fractions  

Kim, Ju Sung (Majors in Plant Resource and Environment, College of Agriculture and Life Sciences, SARI, Jeju National University)
Kim, Kyeoung Cheol (Majors in Plant Resource and Environment, College of Agriculture and Life Sciences, SARI, Jeju National University)
Publication Information
Korean Journal of Medicinal Crop Science / v.24, no.3, 2016 , pp. 222-227 More about this Journal
Abstract
Background: The biological activities of Tradescantia pallida grown in Korea have not been well determined, thus the aim of this study was to investigate the possibility of using it as a medicinal plant. Methods and Results: To investigate the antioxidant activity, ${\alpha}$-glucosidase inhibitory effect and antimicrobial activity of T. pallida, we performed the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity and reducing power assay. This assay for T. pallida leaf extract showed the highest antioxidant activity for the ethyl acetate fraction ($RC_{50}=14.55{\pm}0.16{\mu}g/m{\ell}$ and Abs = 0.613 at $300{\mu}g$). Further, the ethyl acetate fraction exhibited higher ${\alpha}$-glucosidase inhibitory effect with an $IC_{50}$ value of $14.1{\pm}0.1{\mu}g/m{\ell}$ and showed antimicrobial activity against gram positive bacteria (minimum inhibitory concentration = $1,000{\mu}g/m{\ell}$). Conclusions: The ethyl acetate fraction of the crude methanol extract of T. pallida showed remarkable antioxidant activity, ${\alpha}$-glucosidase inhibitory effects and antimicrobial activity. These activities might be related to the flavonoid content in the T. pallida leaf extract.
Keywords
Setcreasea pallida; Tradescantia pallida; Antioxidant Activity; Antimicrobial Activity; ${\alpha}$-Glucosidase Inhibitory Effect;
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