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http://dx.doi.org/10.7783/KJMCS.2011.19.6.484

Antioxidant Activity of Different Solvent Fractions from Prunella vulgaris var. lilacina  

Park, Dong-Sik (Department of Agrofood Resources, NAAS, RDA)
Park, Mi-Young (Department of Agrofood Resources, NAAS, RDA)
Chon, Sang-Min (Department of Agrofood Resources, NAAS, RDA)
Lee, Jin-Young (Department of Agrofood Resources, NAAS, RDA)
Lee, Young-Min (Department of Agrofood Resources, NAAS, RDA)
Jang, Hwan-Hee (Department of Agrofood Resources, NAAS, RDA)
Hwang, Kyung-A (Department of Agrofood Resources, NAAS, RDA)
Kim, Jae-Hyun (Department of Agrofood Resources, NAAS, RDA)
Publication Information
Korean Journal of Medicinal Crop Science / v.19, no.6, 2011 , pp. 484-490 More about this Journal
Abstract
The potential antioxidant activities of different fractions from Prunella vulgaris var. lilacina were assayed in vitro. Among several fractions, n-BuOH fraction showed the highest 1,1-di[henyl-2-picrylhydrazyl (DPPH) free radical scavenging ($IC_{50}=0.50{\mu}g/mL$). The results of 2,2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) radical scavenging activity and ferric reducing antioxidant power (FRAP) assay showed the concentration dependency and n-BuOH fraction appeared a better result than the other fractions at the same concentrati on in this study. Moreover the total phenol and flavonoid contents of n-BuOH fraction contained the highest level. Additionally, correlation analysis indicated a high correlation between the antiradical activity and the total phenolic and flavonoid contents (p < 0.001). It suggests that n-BuOH fraction obtained from the 70% EtOH crude extract of Prunella vulgaris var. lilacina has wide potential for use as a source of antioxidant material.
Keywords
ABTS; DPPH; Flavonoid Contents; Phenolic Contents; Prunella vulgaris var. lilacina;
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