Browse > Article
http://dx.doi.org/10.7783/KJMCS.2011.19.5.388

Antioxidant and Cell Activity Using Extracts of Mume Fructus  

Bae, Yu-Kyung (Department of Beauty Esthetic, Anyang Science University)
Choe, Tae-Boo (Department of Microbial Engineering, Konkuk University)
Publication Information
Korean Journal of Medicinal Crop Science / v.19, no.5, 2011 , pp. 388-394 More about this Journal
Abstract
Mume fructus is the roasted fruits of Prunus mume and has been used as traditional chinese medicine. In this study, mume fructus extracts were prepared by three different methods including hot water extract (sample1), fermentation extract using Lactobacillus (Sample2-LP and sample-LA) and ethanol extract (sample3). Total polyphenol and flavonoid contents were improved by fermentation process, compared to water extract. Sample 3 showed the highest activity in DPPH radical scavenging. The cytotoxicity of the sample 2-LP was in the range of 83.3% cell viability at $300{\mu}g/m{\ell}$ concentration. Mume fructus extracts in a concentration-dependent manner inhibited melanogenesis and NO synthesis was inhibited. Specifically, the extracts fermented by L. plantarum (sample2-LP) showed higher anti-oxidant activity, anti-inflammatory and skin whitening activity than other extracts. It suggests that sample 2-LP could be potentially used as a resource of materials for functional cosmetics.
Keywords
Mume Fructus; Cosmeceutical Activity; Anti-oxidation; Fermentation;
Citations & Related Records
Times Cited By KSCI : 11  (Citation Analysis)
연도 인용수 순위
1 Park HJ. (2010). Study on the cosmeceuticals using enzymetreated red ginseng extracts. Ph.D thesis. Dong Duck Womens University. Seoul, Korea.
2 Park YS. (2002). Antioxidative activities and contents of polyphenolic compound of medicinal herb extracts. Journal of the East Asian Society of Dietary Life. 12:23-31.
3 Seo MH and Bae JH. (2002). Effect of butanol extracts from Prunus mume on the growth of salmonella typhimurium. The Korean Journal Nutrition. 35:926-931.
4 Sim SS. (2003). Effects of citrus essential oils melanin production in B16 melanoma cell. Yakhak Hoeji. 47:25-30.
5 Lee SH, Park KW, Jang HG, Kim CY, Park YS, Kim TC and Heo BG. (2006). Total phenol content, eletron donating ability and tyrosinase inhibition activity of pear cut branch extract. Korean Journal of Horticultural Science & Technology. 24:338- 341.
6 Lim JD, Chang YY, Kim MJ, Song JY, Sun JL, Kim NY and Chung IM. (2004). Comparison of SOD activity and phenolic contents in various korean medicinal plants. Korean Journal of Medicinal Crop Science. 12:191-202.
7 Jeon YH, Kwon JE and Kim MR. (2010). Study on antioxidant and cytotoxic activities in ethanol extract from Prunus mume. Journal of the East Asian Society of Dietary Life. 20:751-758.
8 Marklund S and Marklund G. (1974). Involvement of superoxide anion radical in the autooxidation of pyrogllol and a convenient assay for superoxide dismutase. European Journal of Biochemistry. 47:469-474.   DOI   ScienceOn
9 Park CE. (2006). Inhibition of helicobacter pylori urease activity by mume fructus. Ph.D thesis. Kyung Hee University. Seoul, Korea.
10 Park CG, Bang KH, Lee SE, Cha MS, Sung JS, Park HW and Seong NS. (2001). Antibacterial activity from medicinal plant extracts on the staphylococcus aureus. Korean Journal of Medicinal Crop Science. 9:251-258.
11 Jung SE and Bae JH. (2002). The effect of Prunus mume extracts on the growth of HepG2 and HeLa cell lines. The Korean Journal of Nutrition. 45:439-445.
12 Kim SS, Ha JH, Jeong MH, Ahn JH, Yoon WB, Park SJ, Seong DH and Lee HY. (2009). Comparison of biological activities of fermented Codonopsis lanceolata and fresh Codonopsis lanceolata. Korean Journal of Medicinal Crop Science. 17:280-285.
13 Gutfinger T. (1981). Polyphenols in olive oils. Journal of the American Oil Chemist's Society. 58:966-968.   DOI   ScienceOn
14 Kim YD and Seo KS. (2007). Prunus mume's bioactivity and effect of oriental medicine. Food Preservation and Processing Industry. 6:31-38.
15 Ko BS, Park SK, Choe SB, Jun DW, Jang JS and Park SM. (2004). Hypoglycemic effects of crude extracts of Prunus mume. Journal of the Korean Society of Food Science and Nutrition. 33:951-957.   DOI
16 Kwack YS, Ryu SH, Back BK, Lee JK and Ahn BZ. (1985). The anthelmintic principle of "O-Mae", the roasted fruits of Prunus mume, against clonorchis sinensis. Journal of Pharmaceutical Sciences. 1:75-80.
17 Ha JH, Seo YC, Choi WY, Kim JS, Kim HH, Ahn JH, Lee HY and Jeong MH. (2010). Enhancement of antioxidant activities of bark of herberis Koreana palibin by lactic acid fermentation. Korean Journal of Medicinal Crop Science. 18:421-428.
18 Hwang JY. (2005). Pharmacological effects of maesil(Prunus mume). Food Science and Industry. 38:112-119.
19 Hong YH. (2010). Development of cosmeceuticals using the eneymatic conversion of green tea extracts : focusing on anti-oxidant, anti-wrinkles and whitening effects. Ph.D thesis. Dong Duck Womens University. Seoul, Korea.
20 Hwang HJ, An EM, Back NI, Jo JS and Kim HY. (1998). Isolation and characterization of antioxidative components from mume fructus. Journal of Food Resources Development Institute. 19:28-33.
21 Chung IM, Kim KH and Ahn JK. (1998). Screening of korean medicinal and food plants with antioxidant activity. Korean Journal of Medicinal Crop Science. 6:311-322.
22 Borenfreund and Puemer. (1985). Toxicity determined in vitro by morphological alterations and neutral red absorption. Toxicology. 24:119-124.
23 Choi JH, Kim HM, Song YS, Park SG, Kim JJ and Lee CK. (2007). Physiological effects of the cosmetic product containing of saccharomyces femented modified kyungohkgo extract on human skin. The Korea Association of Herbology. 22:227-232.