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Antioxidant Activities and Skin-Whitening Effects of Nano-encapsuled Water Extract from Rubus coreanus Miquel  

Jeong, Hyang-Suk (College of Bioscience & Biotechnology, Kangwon National Univ.)
Han, Jae-Gun (College of Bioscience & Biotechnology, Kangwon National Univ.)
Han, Ji-Hye (College of Bioscience & Biotechnology, Kangwon National Univ.)
Kim, Young (College of Bioscience & Biotechnology, Kangwon National Univ.)
Oh, Sung-Ho (College of Bioscience & Biotechnology, Kangwon National Univ.)
Kim, Seoung-Seop (College of Bioscience & Biotechnology, Kangwon National Univ.)
Jeong, Myoung-Hoon (College of Bioscience & Biotechnology, Kangwon National Univ.)
Choi, Geun-Pyo (Department of Food Processing & Bakery, Gangwon Provincial Univ.)
Park, Uk-Yeon (Department of Food Processing & Bakery, Gangwon Provincial Univ.)
Lee, Hyeon-Yong (College of Bioscience & Biotechnology, Kangwon National Univ.)
Publication Information
Korean Journal of Medicinal Crop Science / v.17, no.2, 2009 , pp. 83-89 More about this Journal
Abstract
This study was performed to improve antioxidant activities and skin-whitening effects of Rubus coreanus Miquel extracts by nano-encapsulation. R. coreanus was extracted at $60^{\circ}C$ and encapsulated by lecithin and gelagine. Nano-encapsulated extracts showed highest free radical scavengering effect as 97.62% in adding sample ($500\;{\mu}g/m{\ell}$), compared to the extracts from conventional processes. It was showed strong inhibition effect on melanin production test by Clone M-3 cells as 55.23%. High inhibitory potency on tyrosinase was also measured as 155.8% by adding nano-sample of 1 $mg/m{\ell}$. The improvement of biological activity was demonstrated by real time confocal microscope. We could consider that the water soluble extracts of R. coreanus could be definitely enhanced by nano-encapsulated as a potent natural resources for antioxidant and skin-whitening agent.
Keywords
Nano-encapsulation; Rubus coreanus Miquel; Antioxidant Activities; Skin-Whitening Effects;
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Times Cited By KSCI : 7  (Citation Analysis)
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