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Antioxidative Activity and Nitrite Scavenging Ability of Methanol Extract from Salvia plebeia R. Br.  

Lim, Jin-A (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang Uniersity)
Yun, Bo-Won (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang Uniersity)
Baek, Seung-Hwa (Department of Herbal Resources, Professional Graduate School of Oriental Medicine, Wonkwang Uniersity)
Publication Information
Korean Journal of Medicinal Crop Science / v.15, no.3, 2007 , pp. 183-188 More about this Journal
Abstract
Efficacy of antioxidative activity and nitrite scavenging ability of methanol extract from Salvia plebeia was investigated. Electron-donating ability of extract at RC$_{50}$ was 51.10 ${\mu}$g/ml. After addition of 0.92 mg/ml extract, autooxidation of pyrogallol decreased to 62.11% by superoxide dismutase-like activity. In antioxidative activity of extract against linoleic acid during incubation times of 1,2, and 4 days at 40$^{\circ}$, lipid peroxidation values significantly decreased by 72.86%, 77.18%, and 78.32% with addition of 0.2 mg/ml, respectively. Total phenolic content was determined as gallic acid equivalents (GAE) and values revealed as 202.35${\pm}$ 1.26 GAE ${\mu}$g/ml of extract. Nitrite scavenging ability showed the most remark-able effect at pH 1.2, exhibited to 44.29% by addition of 0.2 mg/ml. These results suggest that methanol extract from Salvia plebeia can be used as bioactive and functional materials.
Keywords
Salvia plebeia; Antioxidative activity; Nitrite scavenging ability;
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Times Cited By KSCI : 17  (Citation Analysis)
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