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Increase Effect of Anticancer Activities on Rhodiola sachalinensis A. Bor by the Change of Extraction Process  

Kim, Cheol-Hee (School of Biotechnology and Bioengineering, Kangwon National University)
Kim, Hyo-Sung (School of Biotechnology and Bioengineering, Kangwon National University)
Kwon, Min-Chul (School of Biotechnology and Bioengineering, Kangwon National University)
Bae, Geun-Jung (School of Biotechnology and Bioengineering, Kangwon National University)
Ahn, Jup-Hee (School of Biotechnology and Bioengineering, Kangwon National University)
Lee, Hak-Ju (Divisoion of Wood Chemistry, Korea Forest Research Institute)
Kang, Ha-Young (Divisoion of Wood Chemistry, Korea Forest Research Institute)
Lee, Hyeon-Yong (School of Biotechnology and Bioengineering, Kangwon National University)
Publication Information
Korean Journal of Medicinal Crop Science / v.14, no.6, 2006 , pp. 317-321 More about this Journal
Abstract
This study was performed to compare effect of anticancer activities on Rhodiola sachalinensis by ultrasonifi-cation process and solvent. Compared the yield to the water extracts (WE), wafer extracts with ultrasonification (WEU) at60, loot and ethyl alcohol extracts (EE), ethyl alcohol extracts with ultrasonification (EEU) at 60 ${\circ}$C from Rhodiola sachalinensis. Experimental studies were progressed through the anticancer activities such as cell cytotoxicity, inhibition activities of cell growth. The cell cytotoxicity using human embryonic kidney cell (HEK293) was showed cytotoxicity of below 26.26%by extracts of Rhodiola sachalinensis in 1.0 mg/ml concentration, The anticancer activities were increased in over 70% by extracts of Rhodiola sachalinensis in A549, AGS, Hep3B and MCF-7 cells. From the results, the extract Rhodiola sachalinensis were showed useful anticancer activities.
Keywords
anticancer activities; Rhodiola sachalinensis; ultrasonification;
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