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Antioxidant Activities of Leaf, Stem and Root of Panax ginseng C. A. Meyer  

Lee, Seung-Eun (National Institute of Crop Science. RDA)
Lee, Sung-Woo (National Institute of Crop Science. RDA)
Bang, Jin-Ki (National Institute of Crop Science. RDA)
Yu, Young-Ju (National Institute of Crop Science. RDA)
Seong, Nak-Sul (National Institute of Crop Science. RDA)
Publication Information
Korean Journal of Medicinal Crop Science / v.12, no.3, 2004 , pp. 237-242 More about this Journal
Abstract
To develop a new functional material, leaf, stem and root of Panax gjnseng were analyzed in their antioxidant activities. Root and leaf of ginseng collected from 3 regions, exhibited inhibition activity as $45.2{\sim}54.3%\;and\;90.1{\sim}96.5%$ on peroxidation of low density lipoprotein and linoleic acid, respectively. Scavenging activities of stem, leaf and root of ginseng on superoxide anion radical were $35.6{\sim}76.1%,\;60.1{\sim}69.3%\;and\;-5.6{\sim}20.1%$, respectively. Total phenol contents of leaf, stem and root of ginseng were $147{\sim}200\;mg%,\;110{\sim}153\;mg%\;and\;61{\sim}86\;mg%$ respectively as tannic acid equivalent.
Keywords
Panax ginseng; antioxidant activity; free radical; low density lipoprotein (LDL); peroxidation;
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  • Reference
1 Bioi MS (1958) Antioxidant determinations by the use of a stable free radical. Nature 181:1199-1200   DOI   ScienceOn
2 Cha JY, Kim HJ, Chung CH, Cho YS (1999) Antioxidative activities and contents of polyphenolic compound of Cudrania tricuspidata. J. Korean Soc. Food Sci. Nutr, 28:1310-1315
3 Haraguchi H, Hashimoto K, Yagi A (1992) Antioxidative substances in leaves of Polygonum hydropiper. J. Agric. Food Chern. 40:1349-1351   DOI
4 Kanner J, Mendel H (1977) Prooxidant and antioxidant effects of ascorbic acid and metal salts in a ${\ss}-carotene-linoleate$,model system, J, Food Sci, 42:60-64   DOI
5 Kim MJ, Jung NP (1987) The effect of ginseng saponin on the mouse immune system. Korean J. Ginseng Sci. 11:130-135
6 Kim KH, Lee YS, Jung IS, Park SY, Chung BY, Lee IR, Yun YS (1998) Acidic polysaccharide from Panax ginseng, ginsan, induces Th1 cell and macrophage cytokines and generates LAK cells in synergy with rII-2. Planta Medica 64:110-115   DOI   ScienceOn
7 Kim NM, Sung HS, Kim WJ (1993) Effect of solvents and some extraction conditions on antioxidant activity in cinnamon extracts. Korean J. Food Sci, Technol, 25:204-209
8 Kim JS, Kim KW, Choi KJ, Kwak YK, 1m KS, Lee KM, Chung BY (1996) Screening of antioxidative components from red ginseng saponin, Korean J. Ginseng Sci, 20:173-178
9 Nishikimi M, Rao NA, Yagi K (1972) The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen, Biochem. Biophys Res. Cornmun, 46:849-854   DOI   ScienceOn
10 Cho MZ, Hahn TS, Kwon TB, Oh SK (1989) Antioxidant effect of some chelating agents on soybean oil. J. Korean Agric. Chem. Soc, 32:30-36
11 Zhang D, yasuda T, Yu Y, Zheng P, Kawabata T, Ma Y, Okada S(1996) Ginseng extract scavenges hydroxyl radical and protects unsaturated fatty acids from decomposition caused by iron-mediated lipid peroxidation. Free Radical Biology & Medicine 20:145-150   DOI   ScienceOn
12 Kitagawa I (1983) Chemical studies on crude drug processing.I . On constituents of ginseng radix rubra (1), Yakugaku Zasshi 103:612-622
13 Kang SY, Kim ND (1992) The antihypertensive effect of red ginseng saponin and the endothelium-derived vascular relaxation. Korean J. Ginseng Sci. 16:175-182
14 Lee JW, Sohn HO, Do JH (2000) Function of the water soluble browning reaction products isolated from Korean red ginseng 2. Linoleic acid, Ox-brain autoxidant and $ Fe^{2+}$ ADP/NAD system, J. Ginseng Res. 24:35-40
15 Choi KJ, Kim SC, Kim MW, Nam KY (1987) Identification of saponin and sapogenin in root, leaf and stem of ginseng by thin layer chromatography. J. Korean Agric. Chem, Soc.30:340-344
16 Miller CP, Jirkovsky I, Hayhurst DA, Adelman SJ (1996) In vitro antioxidant effects of estrogens with a hindered 3-OH function on the copper-induced oxidation of low density lipoprotein. Steroids 61:305-308   DOI   ScienceOn
17 Shin JG, Park JW, Pyo lK, Kim MS, Chung MH (1990) Protective effects of a ginseng component, maltol(2-methyl-3-hydroxyl-4-pyrone) against tissue damages induced by oxygen radicals, Korean]. Ginseng Sci. 14:187-190
18 Chai KJ, Kim MW, Hong SK, Kim DH (1983) Effect of solvents on the yield, brown color intensity, UV absorbance, reducing and antioxidant activities of extracts from white and red ginseng. J. Korean Agric, Chem. Soc. 26:8-18
19 Ng TB, Wang H (2001) Panaxagin, a new protein from Chinese ginseng possesses antifungal, anti-viral, translation-inhibiting and ribonuclease activities, Life Science 68:739-749   DOI   ScienceOn
20 Lee J, Lee SR (1994b) Some physiological activity of phenolic substances in plant foods. Korean J. Food Sci. Technol. 26:317-323
21 Kim SI, na JY, Jo DH, Lee CY (1987) Extraction and purification of ginseng oligopeptides with antilipolytic actvities, Korean Agric. Chem Soc, 30:88-94
22 Joo CN, Kim JH (1992) Study on the hypoglycemic action of ginseng saponin on streptozotocin induced diabetic rats ( I ). Korean J. Ginseng Sci. 16: 190-197
23 Park. SN, Choi SW, Boo YC (1990) Effects of f1avonoids of ginseng leaves on erythrocyte membranes against singlet oxygen caused damage. Korean J. Ginseng Sci. 14:191-199
24 Sonoda Y, Ksahara T. Mukaida N, Shimizu N, Tomoda M.Takeda T (1998) Stimulation of interlukin-8 production by acidic polysaccharides from the root of Panax ginseng. Immunopharmacol. 38:287-293   DOI   ScienceOn
25 Oliveira ACC, Perez AC, merino G, Prietp JG, Alvarez AI (2001) ProteGtive effects of Panax ginseng on muscle injury and inflammation after eccentric exercise, Comparative Biochemistry and Physiology Part C 130:369-377
26 Ryu GH (2003) Present status of red ginseng products and its manufacturing process. Food Industry and Nutrition 8:38-42
27 Kiyohara H, Hirano M, Wen XG, Matsumoto T, Sun XB, Yamada H (1994) Charaterisation of an anti-ulcer pectic polysaccharide from leaves of Panax ginseng C. A. Meyer. Carbohydrate Res, 263:89-101   DOI   ScienceOn
28 Lee J, Lee SR (1994a) Analysis of phenolic substances contents in Korean plant foods. Korean J. Food Sci. Technol. 26:310-316
29 Park JD (1996) Recent studies on the chemical constituents of Korean ginseng (Panax ginseng C. A. Meyer). Korean J. Ginseng Sci. 20:389-396
30 Jeon HK, Kim SC, Jung NP (1991) Effects of ginseng saponin fraction and cyclophosphamide on the tumoricidal activity of mouse macrophage and the antitumor effect. Korean J.Ginseng Sci. 15:99-105
31 Wee JJ, Park JD, Kim MW, Lee HJ (1989) Identification of phenolic antioxidant components isolated from Panax ginseng. J. Korean Agric. Chem. Sco. 32:50-56